Motif ID: Tbx4

Z-value: 0.499


Transcription factors associated with Tbx4:

Gene SymbolEntrez IDGene Name
Tbx4 ENSMUSG00000000094.6 Tbx4



Activity profile for motif Tbx4.

activity profile for motif Tbx4


Sorted Z-values histogram for motif Tbx4

Sorted Z-values for motif Tbx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 101 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_125490688 3.315 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr3_+_75557530 1.689 ENSMUST00000161776.1
ENSMUST00000029423.8
 Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr1_+_153665666 1.439 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr1_+_153665274 1.436 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr1_+_6730051 1.294 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr1_+_153665587 1.021 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8
chr2_-_57114970 0.975 ENSMUST00000028166.2
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr13_-_89742490 0.942 ENSMUST00000109546.2
 Vcan
versican
chr1_+_153665627 0.900 ENSMUST00000147482.1
 Rgs8
regulator of G-protein signaling 8
chr6_+_15196949 0.777 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
 Foxp2



forkhead box P2



chr2_-_13011747 0.721 ENSMUST00000061545.5
 C1ql3
C1q-like 3
chr11_-_84068357 0.685 ENSMUST00000100705.4
 Dusp14
dual specificity phosphatase 14
chr11_-_84068766 0.616 ENSMUST00000018792.5
 Dusp14
dual specificity phosphatase 14
chr12_-_31634592 0.496 ENSMUST00000020979.7
ENSMUST00000177962.1
 Bcap29

B cell receptor associated protein 29

chrX_-_162829379 0.466 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
 Txlng


taxilin gamma


chr1_+_6730135 0.465 ENSMUST00000155921.1
 St18
suppression of tumorigenicity 18
chr7_-_103813913 0.460 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr14_-_70642268 0.430 ENSMUST00000022697.5
 Fgf17
fibroblast growth factor 17
chr9_+_86743641 0.429 ENSMUST00000179574.1
 Prss35
protease, serine, 35
chr9_+_35421541 0.414 ENSMUST00000119129.2
 Cdon
cell adhesion molecule-related/down-regulated by oncogenes

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 3.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 1.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0015871 choline transport(GO:0015871)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.3 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.3 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.3 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 3.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0031084 BLOC-2 complex(GO:0031084)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.7 3.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.1 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)