Motif ID: Tead1

Z-value: 0.417


Transcription factors associated with Tead1:

Gene SymbolEntrez IDGene Name
Tead1 ENSMUSG00000055320.10 Tead1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112742025_112742060-0.506.7e-02Click!


Activity profile for motif Tead1.

activity profile for motif Tead1


Sorted Z-values histogram for motif Tead1

Sorted Z-values for motif Tead1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tead1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_6386598 1.020 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
 Dab2




disabled 2, mitogen-responsive phosphoprotein




chr7_-_34133215 0.610 ENSMUST00000038537.8
 Wtip
WT1-interacting protein
chr11_-_100970887 0.595 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr2_+_156775409 0.517 ENSMUST00000088552.6
 Myl9
myosin, light polypeptide 9, regulatory
chr10_+_24595434 0.515 ENSMUST00000020171.5
 Ctgf
connective tissue growth factor
chr15_+_78842632 0.506 ENSMUST00000059619.1
 Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr10_+_24595623 0.498 ENSMUST00000176228.1
ENSMUST00000129142.1
 Ctgf

connective tissue growth factor

chr16_+_91225550 0.401 ENSMUST00000035608.8
 Olig2
oligodendrocyte transcription factor 2
chr6_+_17307040 0.333 ENSMUST00000123439.1
 Cav1
caveolin 1, caveolae protein
chr11_-_32222233 0.332 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr18_+_50030977 0.322 ENSMUST00000145726.1
ENSMUST00000128377.1
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr2_-_164857542 0.280 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chr2_+_19658055 0.279 ENSMUST00000052168.4
 Otud1
OTU domain containing 1
chr6_+_17306415 0.278 ENSMUST00000150901.1
 Cav1
caveolin 1, caveolae protein
chr1_-_87394721 0.270 ENSMUST00000113212.3
 Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr7_+_141216626 0.255 ENSMUST00000141804.1
ENSMUST00000148975.1
 Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr10_+_28074813 0.249 ENSMUST00000166468.1
 Ptprk
protein tyrosine phosphatase, receptor type, K
chr7_-_109616548 0.241 ENSMUST00000077909.1
ENSMUST00000084738.3
 St5

suppression of tumorigenicity 5

chr10_-_87493651 0.231 ENSMUST00000020243.7
 Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr14_-_16575456 0.231 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr6_+_17306335 0.216 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
 Cav1



caveolin 1, caveolae protein



chr13_+_65512678 0.201 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr1_+_51289106 0.189 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr1_+_135766085 0.171 ENSMUST00000038945.5
 Phlda3
pleckstrin homology-like domain, family A, member 3
chr2_-_32712728 0.169 ENSMUST00000009699.9
 Cdk9
cyclin-dependent kinase 9 (CDC2-related kinase)
chr1_+_189728264 0.159 ENSMUST00000097442.2
 Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr2_+_91457501 0.157 ENSMUST00000028689.3
 Lrp4
low density lipoprotein receptor-related protein 4
chr3_-_57575760 0.156 ENSMUST00000029380.7
 Wwtr1
WW domain containing transcription regulator 1
chr5_-_115300912 0.154 ENSMUST00000112090.1
 Dynll1
dynein light chain LC8-type 1
chr8_+_121950492 0.152 ENSMUST00000093078.6
ENSMUST00000170857.1
ENSMUST00000026354.8
ENSMUST00000174753.1
ENSMUST00000172511.1
 Banp




BTG3 associated nuclear protein




chr5_-_115300957 0.143 ENSMUST00000009157.3
 Dynll1
dynein light chain LC8-type 1
chr7_-_90129339 0.139 ENSMUST00000181189.1
 2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr11_+_120721452 0.138 ENSMUST00000018156.5
 Rac3
RAS-related C3 botulinum substrate 3
chr14_-_122913085 0.131 ENSMUST00000162164.1
ENSMUST00000110679.2
ENSMUST00000038075.5
 Ggact


gamma-glutamylamine cyclotransferase


chrX_+_101254528 0.128 ENSMUST00000062000.4
 Foxo4
forkhead box O4
chr14_-_122913751 0.111 ENSMUST00000160401.1
 Ggact
gamma-glutamylamine cyclotransferase
chr8_+_70302761 0.108 ENSMUST00000150968.1
 Cope
coatomer protein complex, subunit epsilon
chr11_+_70700606 0.102 ENSMUST00000137119.2
 Kif1c
kinesin family member 1C
chr19_-_34255325 0.101 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chr6_+_145934113 0.101 ENSMUST00000032383.7
 Sspn
sarcospan
chr8_+_70302518 0.100 ENSMUST00000066469.7
 Cope
coatomer protein complex, subunit epsilon
chr19_-_42128982 0.098 ENSMUST00000161873.1
 Avpi1
arginine vasopressin-induced 1
chr8_-_70700070 0.098 ENSMUST00000116172.1
 Gm11175
predicted gene 11175
chr4_+_141278433 0.092 ENSMUST00000142429.1
 Gm13056
predicted gene 13056
chr11_+_70432627 0.085 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
 Arrb2






arrestin, beta 2






chr4_+_45203921 0.084 ENSMUST00000107804.1
 Frmpd1
FERM and PDZ domain containing 1
chr17_-_71002017 0.081 ENSMUST00000128179.1
ENSMUST00000150456.1
 Myl12a

myosin, light chain 12A, regulatory, non-sarcomeric

chr19_-_42129043 0.080 ENSMUST00000018965.3
 Avpi1
arginine vasopressin-induced 1
chr18_+_82554463 0.074 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
 Mbp










myelin basic protein










chr9_-_8004585 0.073 ENSMUST00000086580.5
ENSMUST00000065353.6
 Yap1

yes-associated protein 1

chr8_+_57511833 0.072 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr15_-_76009440 0.068 ENSMUST00000170153.1
 Fam83h
family with sequence similarity 83, member H
chr7_+_114745685 0.067 ENSMUST00000136645.1
ENSMUST00000169913.1
 Insc

inscuteable homolog (Drosophila)

chr4_-_47057296 0.067 ENSMUST00000107747.1
ENSMUST00000084616.2
 Anks6

ankyrin repeat and sterile alpha motif domain containing 6

chr11_+_70700473 0.064 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
 Kif1c



kinesin family member 1C



chr16_-_4559720 0.060 ENSMUST00000005862.7
 Tfap4
transcription factor AP4
chr11_+_62820469 0.059 ENSMUST00000108703.1
 Trim16
tripartite motif-containing 16
chr11_+_115933282 0.052 ENSMUST00000140991.1
 Sap30bp
SAP30 binding protein
chr11_-_69398226 0.050 ENSMUST00000050140.5
 Tmem88
transmembrane protein 88
chr8_-_70302487 0.048 ENSMUST00000008004.9
 Ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr11_+_69070790 0.045 ENSMUST00000075980.5
ENSMUST00000094081.4
 Tmem107

transmembrane protein 107

chr14_-_54577578 0.039 ENSMUST00000054487.8
 Ajuba
ajuba LIM protein
chr5_+_136967859 0.034 ENSMUST00000001790.5
 Cldn15
claudin 15
chr14_+_30879257 0.033 ENSMUST00000040715.6
 Mustn1
musculoskeletal, embryonic nuclear protein 1
chr17_-_24209377 0.032 ENSMUST00000024931.4
 Ntn3
netrin 3
chr2_+_20519776 0.030 ENSMUST00000114604.2
ENSMUST00000066509.3
 Etl4

enhancer trap locus 4

chr8_-_105966038 0.029 ENSMUST00000116429.2
ENSMUST00000034370.9
 Slc12a4

solute carrier family 12, member 4

chr14_+_70577839 0.027 ENSMUST00000089049.2
 Nudt18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr6_-_37442095 0.027 ENSMUST00000041093.5
 Creb3l2
cAMP responsive element binding protein 3-like 2
chr6_+_34598530 0.026 ENSMUST00000115027.1
ENSMUST00000115026.1
 Cald1

caldesmon 1

chr18_+_60526194 0.023 ENSMUST00000025505.5
 Dctn4
dynactin 4
chr17_+_16972910 0.022 ENSMUST00000071374.5
 BC002059
cDNA sequence BC002059
chr16_-_89508313 0.015 ENSMUST00000056118.2
 Krtap7-1
keratin associated protein 7-1
chr19_+_33822908 0.014 ENSMUST00000042061.6
 Gm5519
predicted pseudogene 5519
chr10_+_126978690 0.013 ENSMUST00000105256.2
 Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr4_+_15265798 0.012 ENSMUST00000062684.8
 Tmem64
transmembrane protein 64
chr6_-_7983424 0.012 ENSMUST00000178598.1
 Gm9825
predicted gene 9825
chr1_+_106171752 0.010 ENSMUST00000061047.6
 Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr9_+_102717668 0.008 ENSMUST00000035121.7
 Amotl2
angiomotin-like 2
chr2_-_168230575 0.002 ENSMUST00000109193.1
 Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr10_-_42276744 0.001 ENSMUST00000105502.1
ENSMUST00000105501.1
 Foxo3

forkhead box O3

chr4_-_62360436 0.000 ENSMUST00000084527.3
ENSMUST00000098033.3
 Fkbp15

FK506 binding protein 15

chr8_+_25720054 0.000 ENSMUST00000068916.8
ENSMUST00000139836.1
 Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 0.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.1 0.6 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0 0.2 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.1 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)