Motif ID: Tead1

Z-value: 0.417


Transcription factors associated with Tead1:

Gene SymbolEntrez IDGene Name
Tead1 ENSMUSG00000055320.10 Tead1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112742025_112742060-0.506.7e-02Click!


Activity profile for motif Tead1.

activity profile for motif Tead1


Sorted Z-values histogram for motif Tead1

Sorted Z-values for motif Tead1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tead1

PNG image of the network

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Top targets:


Showing 1 to 20 of 83 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_6386598 1.020 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
Dab2




disabled 2, mitogen-responsive phosphoprotein




chr7_-_34133215 0.610 ENSMUST00000038537.8
Wtip
WT1-interacting protein
chr11_-_100970887 0.595 ENSMUST00000060792.5
Ptrf
polymerase I and transcript release factor
chr2_+_156775409 0.517 ENSMUST00000088552.6
Myl9
myosin, light polypeptide 9, regulatory
chr10_+_24595434 0.515 ENSMUST00000020171.5
Ctgf
connective tissue growth factor
chr15_+_78842632 0.506 ENSMUST00000059619.1
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr10_+_24595623 0.498 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr16_+_91225550 0.401 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr6_+_17307040 0.333 ENSMUST00000123439.1
Cav1
caveolin 1, caveolae protein
chr11_-_32222233 0.332 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr18_+_50030977 0.322 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr2_-_164857542 0.280 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr2_+_19658055 0.279 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr6_+_17306415 0.278 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr1_-_87394721 0.270 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr7_+_141216626 0.255 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr10_+_28074813 0.249 ENSMUST00000166468.1
Ptprk
protein tyrosine phosphatase, receptor type, K
chr7_-_109616548 0.241 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr10_-_87493651 0.231 ENSMUST00000020243.7
Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr14_-_16575456 0.231 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 1.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 0.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.6 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.1 0.2 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 0.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.1 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)