Motif ID: Tfcp2

Z-value: 1.238


Transcription factors associated with Tfcp2:

Gene SymbolEntrez IDGene Name
Tfcp2 ENSMUSG00000009733.8 Tfcp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfcp2mm10_v2_chr15_-_100551959_1005520100.126.9e-01Click!


Activity profile for motif Tfcp2.

activity profile for motif Tfcp2


Sorted Z-values histogram for motif Tfcp2

Sorted Z-values for motif Tfcp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfcp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_85578070 3.063 ENSMUST00000109424.2
 Wnt7b
wingless-related MMTV integration site 7B
chr10_-_64090241 2.994 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_-_64090265 2.717 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr11_-_22001605 2.684 ENSMUST00000006071.7
 Otx1
orthodenticle homolog 1 (Drosophila)
chr9_+_50856924 2.293 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
 Ppp2r1b






protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform






chr15_-_11905609 1.752 ENSMUST00000066529.3
 Npr3
natriuretic peptide receptor 3
chr2_-_102186322 1.579 ENSMUST00000111222.1
ENSMUST00000058790.5
 Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr11_+_75531690 1.459 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
 Slc43a2



solute carrier family 43, member 2



chr9_-_96862903 1.392 ENSMUST00000121077.1
ENSMUST00000124923.1
 Acpl2

acid phosphatase-like 2

chr5_+_124629050 1.280 ENSMUST00000037865.8
 Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
chr9_+_27299205 1.214 ENSMUST00000115247.1
ENSMUST00000133213.1
 Igsf9b

immunoglobulin superfamily, member 9B

chr17_+_36837123 1.074 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
 Trim26





tripartite motif-containing 26





chr6_+_14901344 1.045 ENSMUST00000115477.1
 Foxp2
forkhead box P2
chr6_+_14901440 1.005 ENSMUST00000128567.1
 Foxp2
forkhead box P2
chr11_-_84067063 0.971 ENSMUST00000108101.1
 Dusp14
dual specificity phosphatase 14
chr7_+_96211656 0.946 ENSMUST00000107165.1
 Tenm4
teneurin transmembrane protein 4
chr2_+_163225363 0.934 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr8_+_120488416 0.919 ENSMUST00000034279.9
 Gse1
genetic suppressor element 1
chr10_+_3366125 0.881 ENSMUST00000043374.5
 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr1_+_165302625 0.858 ENSMUST00000111450.1
 Gpr161
G protein-coupled receptor 161

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.7 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
1.0 3.1 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.0 3.0 GO:0015807 L-amino acid transport(GO:0015807)
0.3 2.7 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.2 2.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 2.0 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.4 1.8 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 1.7 GO:0070613 regulation of protein processing(GO:0070613)
0.2 1.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 1.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.1 1.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 1.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.1 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.2 1.0 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 1.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.0 GO:0097178 ruffle assembly(GO:0097178)
0.2 0.9 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.9 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 0.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 1.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.2 GO:0070688 MLL5-L complex(GO:0070688)
0.2 1.0 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.0 GO:0005652 nuclear lamina(GO:0005652)
0.0 1.0 GO:0030425 dendrite(GO:0030425)
0.2 0.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.8 3.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 3.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 2.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 2.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 1.8 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 1.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 1.0 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.0 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.2 0.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 0.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)