Motif ID: Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2

Z-value: 0.890

Transcription factors associated with Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2:

Gene SymbolEntrez IDGene Name
Bhlhe41 ENSMUSG00000030256.5 Bhlhe41
Srebf1 ENSMUSG00000020538.9 Srebf1
Srebf2 ENSMUSG00000022463.7 Srebf2
Tfeb ENSMUSG00000023990.12 Tfeb
Usf1 ENSMUSG00000026641.7 Usf1
Usf2 ENSMUSG00000058239.7 Usf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Srebf2mm10_v2_chr15_+_82147238_82147275-0.479.1e-02Click!
Tfebmm10_v2_chr17_+_47737030_477371070.421.4e-01Click!
Usf1mm10_v2_chr1_+_171411305_171411337-0.391.7e-01Click!
Usf2mm10_v2_chr7_-_30956742_309568030.185.3e-01Click!
Srebf1mm10_v2_chr11_-_60210410_60210465-0.058.5e-01Click!


Activity profile for motif Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2.

activity profile for motif Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2


Sorted Z-values histogram for motif Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2

Sorted Z-values for motif Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_66077022 2.834 ENSMUST00000150766.1
ENSMUST00000038116.5
 Ankrd12

ankyrin repeat domain 12

chr4_-_34882919 2.617 ENSMUST00000098163.2
ENSMUST00000047950.5
 Zfp292

zinc finger protein 292

chr9_-_87255536 2.064 ENSMUST00000093802.4
 4922501C03Rik
RIKEN cDNA 4922501C03 gene
chr7_+_46796088 2.061 ENSMUST00000006774.4
ENSMUST00000165031.1
 Gtf2h1

general transcription factor II H, polypeptide 1

chr2_-_164833438 2.004 ENSMUST00000042775.4
 Neurl2
neuralized-like 2 (Drosophila)
chr10_-_62792243 1.855 ENSMUST00000020268.5
 Ccar1
cell division cycle and apoptosis regulator 1
chr15_+_66577536 1.822 ENSMUST00000048188.8
 Phf20l1
PHD finger protein 20-like 1
chr8_+_41239718 1.651 ENSMUST00000045218.7
 Pcm1
pericentriolar material 1
chr12_+_65036319 1.630 ENSMUST00000120580.1
 Prpf39
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr11_+_49203465 1.570 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
 Zfp62


zinc finger protein 62


chr4_+_127077374 1.568 ENSMUST00000046751.6
ENSMUST00000094713.3
 Zmym6

zinc finger, MYM-type 6

chr10_+_111164794 1.556 ENSMUST00000105275.1
ENSMUST00000095310.1
 Osbpl8

oxysterol binding protein-like 8

chr19_+_53600377 1.500 ENSMUST00000025930.9
 Smc3
structural maintenance of chromosomes 3
chr18_-_6135888 1.488 ENSMUST00000182383.1
ENSMUST00000062584.7
ENSMUST00000077128.6
ENSMUST00000182038.1
ENSMUST00000182213.1
 Arhgap12




Rho GTPase activating protein 12




chr7_-_46795881 1.464 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
 Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr2_-_74578875 1.428 ENSMUST00000134168.1
ENSMUST00000111993.2
ENSMUST00000064503.6
 Lnp


limb and neural patterns


chr11_+_54438188 1.413 ENSMUST00000046835.7
 Fnip1
folliculin interacting protein 1
chr19_-_60790692 1.413 ENSMUST00000025955.6
 Eif3a
eukaryotic translation initiation factor 3, subunit A
chr15_-_3995708 1.411 ENSMUST00000046633.8
 AW549877
expressed sequence AW549877
chr12_+_72441933 1.390 ENSMUST00000161284.1
 Lrrc9
leucine rich repeat containing 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 237 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.4 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.7 2.7 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 2.5 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.1 2.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 2.0 GO:0034453 microtubule anchoring(GO:0034453)
0.2 1.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 1.7 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 1.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.5 1.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.4 1.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.2 1.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.6 GO:0045214 sarcomere organization(GO:0045214)
0.4 1.5 GO:0070829 heterochromatin maintenance(GO:0070829)
0.3 1.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 1.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.5 1.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.3 1.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 1.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 1.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.2 1.3 GO:1903753 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) negative regulation of p38MAPK cascade(GO:1903753)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.4 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.2 2.7 GO:0043196 varicosity(GO:0043196)
0.3 2.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.7 2.0 GO:0005927 muscle tendon junction(GO:0005927)
0.2 1.8 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 1.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 1.6 GO:0033503 HULC complex(GO:0033503)
0.1 1.6 GO:0000242 pericentriolar material(GO:0000242)
0.3 1.5 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.2 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.4 GO:0000243 commitment complex(GO:0000243)
0.1 1.4 GO:0010369 chromocenter(GO:0010369)
0.3 1.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 153 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0005096 GTPase activator activity(GO:0005096)
0.7 3.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 2.7 GO:0017022 myosin binding(GO:0017022)
0.1 2.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 2.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 1.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.5 1.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.4 1.5 GO:0036033 mediator complex binding(GO:0036033)
0.1 1.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.3 GO:0008565 protein transporter activity(GO:0008565)
0.2 1.2 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)