Motif ID: Tgif1_Meis3

Z-value: 1.522

Transcription factors associated with Tgif1_Meis3:

Gene SymbolEntrez IDGene Name
Meis3 ENSMUSG00000041420.12 Meis3
Tgif1 ENSMUSG00000047407.11 Tgif1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tgif1mm10_v2_chr17_-_70851710_708517380.525.9e-02Click!
Meis3mm10_v2_chr7_+_16175085_161751390.078.1e-01Click!


Activity profile for motif Tgif1_Meis3.

activity profile for motif Tgif1_Meis3


Sorted Z-values histogram for motif Tgif1_Meis3

Sorted Z-values for motif Tgif1_Meis3



Network of associatons between targets according to the STRING database.



First level regulatory network of Tgif1_Meis3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_102254739 3.335 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr4_-_82705735 2.529 ENSMUST00000155821.1
 Nfib
nuclear factor I/B
chr4_+_102254993 2.414 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr3_+_26331150 2.401 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene
chr10_+_69787431 2.172 ENSMUST00000183240.1
 Ank3
ankyrin 3, epithelial
chr15_-_66831625 2.106 ENSMUST00000164163.1
 Sla
src-like adaptor
chr15_-_66801577 2.077 ENSMUST00000168589.1
 Sla
src-like adaptor
chr18_+_34247685 1.985 ENSMUST00000066133.6
 Apc
adenomatosis polyposis coli
chr11_+_105589970 1.943 ENSMUST00000168598.1
ENSMUST00000100330.3
 Tanc2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr10_+_36506814 1.729 ENSMUST00000167191.1
ENSMUST00000058738.4
 Hs3st5

heparan sulfate (glucosamine) 3-O-sulfotransferase 5

chr19_-_57182293 1.655 ENSMUST00000133369.1
 Ablim1
actin-binding LIM protein 1
chr7_+_49246131 1.652 ENSMUST00000064395.6
 Nav2
neuron navigator 2
chr18_+_59175333 1.607 ENSMUST00000080721.4
 Chsy3
chondroitin sulfate synthase 3
chr15_+_44196135 1.591 ENSMUST00000038856.6
ENSMUST00000110289.3
 Trhr

thyrotropin releasing hormone receptor

chr7_-_137314394 1.574 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr10_+_36507013 1.565 ENSMUST00000168572.1
 Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr10_-_64090241 1.558 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr11_+_77518566 1.555 ENSMUST00000147386.1
 Abhd15
abhydrolase domain containing 15
chrX_+_104482774 1.528 ENSMUST00000087867.5
 Uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr10_-_64090265 1.486 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 467 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 8.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 5.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 4.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.5 3.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 3.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.5 3.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 3.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 3.2 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.6 2.6 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.8 2.5 GO:0016191 synaptic vesicle uncoating(GO:0016191) regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.6 2.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 2.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.8 2.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 2.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 2.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.7 2.2 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.3 2.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.5 2.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.5 1.9 GO:0060915 fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 1.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 164 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 7.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 4.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 3.9 GO:0030427 site of polarized growth(GO:0030427)
0.2 3.5 GO:0043196 varicosity(GO:0043196)
0.1 3.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 3.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.2 GO:0060076 excitatory synapse(GO:0060076)
0.0 3.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 2.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 2.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 2.3 GO:0043083 synaptic cleft(GO:0043083)
0.2 2.1 GO:0042587 glycogen granule(GO:0042587)
0.0 2.1 GO:0005801 cis-Golgi network(GO:0005801)
0.2 2.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 2.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.0 GO:0005814 centriole(GO:0005814)
0.1 1.9 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.9 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 294 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.0 GO:0030552 cAMP binding(GO:0030552)
0.1 4.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 3.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3 3.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.5 3.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 3.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 3.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 2.6 GO:0005518 collagen binding(GO:0005518)
0.4 2.5 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 2.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.4 GO:0008017 microtubule binding(GO:0008017)
0.1 2.3 GO:0032452 histone demethylase activity(GO:0032452)
0.1 2.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 2.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 2.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)