Motif ID: Tgif2_Tgif2lx1_Tgif2lx2
Z-value: 1.048
Transcription factors associated with Tgif2_Tgif2lx1_Tgif2lx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tgif2 | ENSMUSG00000062175.7 | Tgif2 |
Tgif2lx1 | ENSMUSG00000061283.4 | Tgif2lx1 |
Tgif2lx2 | ENSMUSG00000063242.6 | Tgif2lx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tgif2 | mm10_v2_chr2_+_156840077_156840141 | 0.39 | 1.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 5.2 | GO:1903181 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) |
1.2 | 5.8 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) |
0.4 | 1.6 | GO:0006842 | tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) |
0.3 | 1.0 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.2 | 1.6 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
0.2 | 1.0 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.1 | 1.2 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
0.1 | 1.4 | GO:0035999 | tetrahydrofolate interconversion(GO:0035999) |
0.1 | 1.5 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
0.1 | 0.6 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.1 | 2.3 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
0.1 | 0.6 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.1 | 0.3 | GO:0060023 | soft palate development(GO:0060023) |
0.1 | 1.9 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
0.1 | 1.7 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.1 | 0.4 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
0.1 | 0.5 | GO:0042701 | progesterone secretion(GO:0042701) |
0.1 | 0.7 | GO:0048478 | replication fork protection(GO:0048478) |
0.1 | 0.3 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.1 | 1.0 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
0.1 | 0.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 0.5 | GO:0002591 | positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) |
0.1 | 0.3 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.1 | 0.2 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
0.1 | 0.4 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.1 | 0.5 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.1 | 1.6 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
0.1 | 0.6 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.1 | 0.2 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.1 | 1.3 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.1 | 1.5 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.0 | 0.3 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.0 | 0.6 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.0 | 0.4 | GO:0046415 | urate metabolic process(GO:0046415) |
0.0 | 0.5 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.0 | 1.1 | GO:0030224 | monocyte differentiation(GO:0030224) |
0.0 | 1.1 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.3 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.0 | 1.5 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.0 | 0.8 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 0.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.0 | 1.7 | GO:0030901 | midbrain development(GO:0030901) |
0.0 | 1.0 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
0.0 | 0.6 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.0 | 0.1 | GO:0048239 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
0.0 | 0.3 | GO:0097284 | hepatocyte apoptotic process(GO:0097284) |
0.0 | 0.7 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
0.0 | 0.1 | GO:0015808 | L-alanine transport(GO:0015808) |
0.0 | 0.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.0 | 0.1 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
0.0 | 1.5 | GO:0042698 | ovulation cycle(GO:0042698) |
0.0 | 0.2 | GO:0036376 | sodium ion export from cell(GO:0036376) |
0.0 | 0.3 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
0.0 | 0.9 | GO:0035690 | cellular response to drug(GO:0035690) |
0.0 | 0.2 | GO:0045187 | regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
0.0 | 0.1 | GO:0009146 | purine nucleoside triphosphate catabolic process(GO:0009146) |
0.0 | 0.3 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.0 | 0.2 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
0.0 | 0.2 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.1 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.4 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 0.6 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.6 | GO:0097513 | myosin II filament(GO:0097513) |
0.1 | 0.7 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 1.0 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
0.1 | 0.7 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.1 | 1.3 | GO:0000124 | SAGA complex(GO:0000124) |
0.1 | 1.0 | GO:0030312 | external encapsulating structure(GO:0030312) |
0.1 | 0.6 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.1 | 0.5 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 0.2 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.9 | GO:0097546 | ciliary base(GO:0097546) |
0.0 | 1.9 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 5.2 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 0.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.0 | 0.3 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.3 | GO:0031045 | dense core granule(GO:0031045) |
0.0 | 0.3 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 0.2 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 8.0 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.6 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 0.1 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) post-mRNA release spliceosomal complex(GO:0071014) |
0.0 | 1.1 | GO:0005795 | Golgi stack(GO:0005795) |
0.0 | 0.2 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.6 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.1 | GO:0098536 | deuterosome(GO:0098536) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.5 | 5.8 | GO:0003680 | AT DNA binding(GO:0003680) |
0.5 | 1.4 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.4 | 5.2 | GO:0050897 | cobalt ion binding(GO:0050897) |
0.3 | 1.0 | GO:0004568 | chitinase activity(GO:0004568) |
0.2 | 1.1 | GO:0016151 | nickel cation binding(GO:0016151) |
0.1 | 0.4 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.1 | 2.3 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
0.1 | 0.5 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 0.5 | GO:0015440 | peptide-transporting ATPase activity(GO:0015440) |
0.1 | 1.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 1.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 1.0 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.1 | 0.3 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.1 | 0.2 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.1 | 1.5 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.1 | 0.6 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.1 | 1.2 | GO:0052890 | oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890) |
0.1 | 0.9 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.0 | 0.4 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.6 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 0.2 | GO:0046790 | virion binding(GO:0046790) |
0.0 | 0.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 1.1 | GO:0005272 | sodium channel activity(GO:0005272) |
0.0 | 1.1 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 0.5 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 1.5 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.1 | GO:1990460 | leptin receptor binding(GO:1990460) |
0.0 | 0.2 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
0.0 | 1.1 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.0 | 0.1 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
0.0 | 0.8 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.2 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.0 | 1.3 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.1 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.0 | 0.1 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.0 | 0.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.0 | 0.7 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.7 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |