Motif ID: Thra

Z-value: 0.970


Transcription factors associated with Thra:

Gene SymbolEntrez IDGene Name
Thra ENSMUSG00000058756.7 Thra

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thramm10_v2_chr11_+_98741871_987418940.303.0e-01Click!


Activity profile for motif Thra.

activity profile for motif Thra


Sorted Z-values histogram for motif Thra

Sorted Z-values for motif Thra



Network of associatons between targets according to the STRING database.



First level regulatory network of Thra

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_81333129 5.060 ENSMUST00000085238.6
ENSMUST00000182208.1
 Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr12_+_44328882 2.477 ENSMUST00000020939.8
ENSMUST00000110748.2
 Nrcam

neuron-glia-CAM-related cell adhesion molecule

chrX_-_166585679 2.473 ENSMUST00000000412.2
 Egfl6
EGF-like-domain, multiple 6
chrX_+_86191764 2.373 ENSMUST00000026036.4
 Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr7_-_141214080 1.735 ENSMUST00000026573.5
ENSMUST00000170841.1
 1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr7_-_73537621 1.624 ENSMUST00000172704.1
 Chd2
chromodomain helicase DNA binding protein 2
chr10_+_93641041 1.559 ENSMUST00000020204.4
 Ntn4
netrin 4
chr11_+_67586675 1.542 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr17_-_66449715 1.537 ENSMUST00000086693.5
ENSMUST00000097291.3
 Soga2

SOGA family member 2

chr13_+_44729794 1.448 ENSMUST00000172830.1
 Jarid2
jumonji, AT rich interactive domain 2
chr11_+_7063423 1.397 ENSMUST00000020706.4
 Adcy1
adenylate cyclase 1
chr8_+_120537423 1.341 ENSMUST00000118136.1
 Gse1
genetic suppressor element 1
chr11_+_67586520 1.216 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr12_-_111672290 1.195 ENSMUST00000001304.7
 Ckb
creatine kinase, brain
chr7_+_35802593 1.193 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr5_-_24995748 1.191 ENSMUST00000076306.5
 Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr2_+_102706356 1.187 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
 Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr12_+_86678685 1.154 ENSMUST00000021681.3
 Vash1
vasohibin 1
chr9_+_107906866 1.083 ENSMUST00000035203.7
 Mst1r
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr10_+_80148263 1.056 ENSMUST00000099492.3
ENSMUST00000042057.5
 Midn

midnolin


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 84 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 5.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 3.0 GO:0008360 regulation of cell shape(GO:0008360)
0.4 2.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 2.4 GO:0035902 response to immobilization stress(GO:0035902)
0.0 2.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.2 2.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.9 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.3 1.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.3 GO:0007616 long-term memory(GO:0007616)
0.3 1.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 1.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 1.2 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 1.2 GO:0033344 cholesterol efflux(GO:0033344)
0.2 1.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 1.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 1.1 GO:0006611 protein export from nucleus(GO:0006611)
0.3 1.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.9 GO:0005604 basement membrane(GO:0005604)
0.0 3.3 GO:0001726 ruffle(GO:0001726)
0.1 2.7 GO:0030673 axolemma(GO:0030673)
0.2 2.5 GO:0043194 axon initial segment(GO:0043194)
0.2 2.4 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.8 GO:0032420 stereocilium(GO:0032420)
0.1 1.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.1 GO:0032982 myosin filament(GO:0032982)
0.2 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 0.6 GO:0032437 cuticular plate(GO:0032437)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 5.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.5 2.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 2.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 2.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 2.0 GO:0051015 actin filament binding(GO:0051015)
0.0 1.9 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.6 GO:0043237 laminin-1 binding(GO:0043237)
0.0 1.6 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.2 1.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 1.2 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.1 GO:0051087 chaperone binding(GO:0051087)
0.3 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 0.9 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.2 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.9 GO:0032795 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)