Motif ID: Tlx1

Z-value: 0.885


Transcription factors associated with Tlx1:

Gene SymbolEntrez IDGene Name
Tlx1 ENSMUSG00000025215.9 Tlx1



Activity profile for motif Tlx1.

activity profile for motif Tlx1


Sorted Z-values histogram for motif Tlx1

Sorted Z-values for motif Tlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tlx1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_16011851 1.302 ENSMUST00000042603.6
 Inhba
inhibin beta-A
chr10_+_86302854 1.279 ENSMUST00000132307.1
 Timp3
tissue inhibitor of metalloproteinase 3
chr5_-_67815852 1.255 ENSMUST00000141443.1
 Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr1_-_126830786 0.943 ENSMUST00000162646.1
 Nckap5
NCK-associated protein 5
chr12_+_95692212 0.894 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr2_+_82053222 0.871 ENSMUST00000047527.7
 Zfp804a
zinc finger protein 804A
chr3_+_134236483 0.848 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr12_-_91746020 0.827 ENSMUST00000166967.1
 Ston2
stonin 2
chr11_+_97450136 0.783 ENSMUST00000107601.1
 Arhgap23
Rho GTPase activating protein 23
chr12_+_71048338 0.755 ENSMUST00000135709.1
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr8_-_109251698 0.752 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr4_+_136284658 0.744 ENSMUST00000144217.1
 Zfp46
zinc finger protein 46
chr18_+_86711520 0.717 ENSMUST00000122464.1
 Cbln2
cerebellin 2 precursor protein
chr10_+_69785507 0.698 ENSMUST00000182993.1
 Ank3
ankyrin 3, epithelial
chr1_-_126830632 0.674 ENSMUST00000112583.1
ENSMUST00000094609.3
 Nckap5

NCK-associated protein 5

chr8_-_57962564 0.648 ENSMUST00000098757.3
 Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr8_-_67818218 0.627 ENSMUST00000059374.4
 Psd3
pleckstrin and Sec7 domain containing 3
chr16_-_76373827 0.625 ENSMUST00000121927.1
 Nrip1
nuclear receptor interacting protein 1
chr18_+_33464163 0.623 ENSMUST00000097634.3
 Gm10549
predicted gene 10549
chr2_-_150451486 0.621 ENSMUST00000109916.1
 Zfp442
zinc finger protein 442

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 1.3 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799)
0.2 1.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.2 0.7 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.6 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.6 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 0.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 1.3 GO:0043512 inhibin A complex(GO:0043512)
0.0 1.0 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
0.1 0.4 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)