Motif ID: Trp53
Z-value: 0.824
Transcription factors associated with Trp53:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Trp53 | ENSMUSG00000059552.7 | Trp53 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Trp53 | mm10_v2_chr11_+_69580392_69580419 | 0.52 | 5.9e-02 | Click! |
Top targets:
Showing 1 to 20 of 169 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 54 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.2 | 2.0 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.4 | 1.6 | GO:0060266 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268) |
| 0.4 | 1.6 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.2 | 1.2 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
| 0.1 | 1.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.2 | 1.0 | GO:0099624 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624) |
| 0.0 | 0.8 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.2 | 0.7 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) |
| 0.1 | 0.7 | GO:0042435 | indole-containing compound biosynthetic process(GO:0042435) |
| 0.0 | 0.7 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
| 0.2 | 0.6 | GO:0070488 | neutrophil aggregation(GO:0070488) |
| 0.2 | 0.6 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.1 | 0.6 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.1 | 0.4 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 0.1 | 0.4 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
| 0.1 | 0.4 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.0 | 0.4 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 0.4 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.0 | 0.4 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
Gene overrepresentation in cellular_component category:
Showing 1 to 18 of 18 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.2 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.0 | 1.9 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 1.7 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 1.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 1.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.3 | 1.2 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
| 0.0 | 1.2 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 1.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.3 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 0.2 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
| 0.0 | 0.2 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.0 | 0.2 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.1 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.0 | 0.1 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.1 | GO:0045179 | apical cortex(GO:0045179) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 30 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.4 | 1.6 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 1.6 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 1.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 1.2 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.0 | 1.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.2 | 1.0 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.2 | 0.7 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.0 | 0.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.2 | 0.6 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 0.6 | GO:0050786 | arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786) |
| 0.1 | 0.4 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
| 0.1 | 0.4 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.1 | 0.4 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.1 | 0.3 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.1 | 0.3 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.0 | 0.3 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.3 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.0 | 0.3 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.1 | 0.2 | GO:0070051 | fibrinogen binding(GO:0070051) |
