Motif ID: Trp53

Z-value: 0.824


Transcription factors associated with Trp53:

Gene SymbolEntrez IDGene Name
Trp53 ENSMUSG00000059552.7 Trp53

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp53mm10_v2_chr11_+_69580392_695804190.525.9e-02Click!


Activity profile for motif Trp53.

activity profile for motif Trp53


Sorted Z-values histogram for motif Trp53

Sorted Z-values for motif Trp53



Network of associatons between targets according to the STRING database.



First level regulatory network of Trp53

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_69206146 1.211 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr2_-_69206133 0.999 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chrX_-_142306170 0.987 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr17_+_3532554 0.985 ENSMUST00000168560.1
Cldn20
claudin 20
chr15_-_98004634 0.938 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr18_+_61639542 0.847 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr17_-_33890584 0.833 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chr1_-_184883218 0.832 ENSMUST00000048308.5
C130074G19Rik
RIKEN cDNA C130074G19 gene
chr15_-_98004695 0.780 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr14_+_13453937 0.759 ENSMUST00000153954.1
Synpr
synaptoporin
chr7_-_141010759 0.754 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr17_-_33890539 0.736 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr9_-_100486788 0.708 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr7_-_114927726 0.697 ENSMUST00000059737.2
Gm6816
predicted gene 6816
chr14_-_55944536 0.690 ENSMUST00000022834.6
Cma1
chymase 1, mast cell
chr14_+_73237891 0.685 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr11_+_116593687 0.680 ENSMUST00000153476.1
Aanat
arylalkylamine N-acetyltransferase
chr1_+_6487231 0.672 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr14_+_13454010 0.645 ENSMUST00000112656.2
Synpr
synaptoporin
chr14_-_54926784 0.644 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr12_-_70231414 0.626 ENSMUST00000161083.1
Pygl
liver glycogen phosphorylase
chr3_+_90669063 0.616 ENSMUST00000069927.8
S100a8
S100 calcium binding protein A8 (calgranulin A)
chr4_-_83285141 0.613 ENSMUST00000150522.1
Ttc39b
tetratricopeptide repeat domain 39B
chr7_+_24884809 0.608 ENSMUST00000156372.1
ENSMUST00000124035.1
Rps19

ribosomal protein S19

chr2_-_164857542 0.595 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr7_-_97332017 0.562 ENSMUST00000139582.2
Usp35
ubiquitin specific peptidase 35
chr2_+_10372426 0.560 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2


Scm-like with four mbt domains 2


chr8_+_94977101 0.516 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr15_+_85859689 0.503 ENSMUST00000170629.1
Gtse1
G two S phase expressed protein 1
chr7_+_24884651 0.495 ENSMUST00000153451.2
ENSMUST00000108429.1
Rps19

ribosomal protein S19

chr9_-_114982739 0.475 ENSMUST00000053150.5
Gm9846
predicted gene 9846
chr7_+_24884611 0.472 ENSMUST00000108428.1
Rps19
ribosomal protein S19
chr5_-_116422858 0.453 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr10_+_110745433 0.441 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7



E2F transcription factor 7



chr14_+_74735641 0.428 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr19_+_46328179 0.424 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chr10_-_81350389 0.420 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr10_-_81350191 0.410 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr11_-_3527916 0.390 ENSMUST00000020718.4
Smtn
smoothelin
chr2_-_130664565 0.389 ENSMUST00000089559.4
Ddrgk1
DDRGK domain containing 1
chr14_-_70653081 0.369 ENSMUST00000062629.4
Npm2
nucleophosmin/nucleoplasmin 2
chr10_-_81350305 0.369 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr17_+_87282880 0.366 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr4_-_96591555 0.363 ENSMUST00000055693.8
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr9_+_66946057 0.350 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr14_+_47001336 0.347 ENSMUST00000125113.1
Samd4
sterile alpha motif domain containing 4
chr4_+_116596672 0.344 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr5_+_34989473 0.343 ENSMUST00000114284.1
ENSMUST00000114285.1
Rgs12

regulator of G-protein signaling 12

chr7_+_47050628 0.340 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr1_+_82339049 0.336 ENSMUST00000140020.1
Rhbdd1
rhomboid domain containing 1
chr7_+_130936172 0.332 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr5_+_34999046 0.318 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr5_-_115194283 0.314 ENSMUST00000112113.1
Cabp1
calcium binding protein 1
chr9_+_107576915 0.310 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr2_-_155074447 0.303 ENSMUST00000137242.1
ENSMUST00000054607.9
Ahcy

S-adenosylhomocysteine hydrolase

chr17_+_35821675 0.302 ENSMUST00000003635.6
Ier3
immediate early response 3
chr9_+_72438534 0.301 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr17_+_32506446 0.300 ENSMUST00000165999.1
Cyp4f17
cytochrome P450, family 4, subfamily f, polypeptide 17
chr8_-_105851981 0.300 ENSMUST00000040776.4
Cenpt
centromere protein T
chr4_+_139622842 0.298 ENSMUST00000039818.9
Aldh4a1
aldehyde dehydrogenase 4 family, member A1
chr6_-_134897815 0.284 ENSMUST00000165392.1
ENSMUST00000046255.7
ENSMUST00000111932.1
ENSMUST00000116515.2
Gpr19



G protein-coupled receptor 19



chr5_+_34999111 0.278 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr17_-_21933022 0.276 ENSMUST00000074295.7
Zfp942
zinc finger protein 942
chr12_-_55492587 0.270 ENSMUST00000021413.7
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr15_-_102350692 0.264 ENSMUST00000041208.7
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr11_+_118476824 0.264 ENSMUST00000135383.2
Engase
endo-beta-N-acetylglucosaminidase
chr9_-_21963568 0.264 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr5_+_34999070 0.256 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr2_+_152962485 0.253 ENSMUST00000099197.2
ENSMUST00000103155.3
Ttll9

tubulin tyrosine ligase-like family, member 9

chr2_-_127521358 0.249 ENSMUST00000028850.8
ENSMUST00000103215.4
Kcnip3

Kv channel interacting protein 3, calsenilin

chr13_+_113317084 0.246 ENSMUST00000136755.2
BC067074
cDNA sequence BC067074
chr2_-_155592567 0.239 ENSMUST00000155347.1
ENSMUST00000130881.1
ENSMUST00000079691.6
Gss


glutathione synthetase


chr17_+_26917091 0.229 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr4_-_135573623 0.219 ENSMUST00000105855.1
Grhl3
grainyhead-like 3 (Drosophila)
chr17_-_34862473 0.219 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb


complement factor B


chr2_+_72285637 0.215 ENSMUST00000090824.5
ENSMUST00000135469.1
Zak

sterile alpha motif and leucine zipper containing kinase AZK

chr4_+_115057410 0.207 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr3_+_96172327 0.204 ENSMUST00000076372.4
Sf3b4
splicing factor 3b, subunit 4
chr11_-_102469839 0.192 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr19_-_47138280 0.185 ENSMUST00000140512.1
ENSMUST00000035822.1
Calhm2

calcium homeostasis modulator 2

chr19_-_45591820 0.179 ENSMUST00000160003.1
ENSMUST00000162879.1
Fbxw4

F-box and WD-40 domain protein 4

chr2_-_150362708 0.173 ENSMUST00000051153.5
3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr11_-_98438941 0.173 ENSMUST00000002655.7
Mien1
migration and invasion enhancer 1
chr6_+_127446819 0.169 ENSMUST00000112191.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr8_+_68880491 0.169 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr6_+_39592569 0.164 ENSMUST00000135671.1
ENSMUST00000119379.1
Ndufb2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2

chr10_+_80622677 0.163 ENSMUST00000079773.6
Csnk1g2
casein kinase 1, gamma 2
chr15_-_77927728 0.157 ENSMUST00000174468.1
ENSMUST00000174529.1
ENSMUST00000173631.1
Txn2


thioredoxin 2


chr4_-_129641060 0.156 ENSMUST00000046425.9
ENSMUST00000133803.1
Txlna

taxilin alpha

chr11_-_102925086 0.156 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr14_+_70577839 0.154 ENSMUST00000089049.2
Nudt18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr3_-_146495115 0.145 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr7_+_16309577 0.143 ENSMUST00000002152.6
Bbc3
BCL2 binding component 3
chr4_-_129640959 0.142 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
Txlna


taxilin alpha


chr4_-_43030440 0.142 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chr5_-_38480131 0.141 ENSMUST00000143758.1
ENSMUST00000067886.5
Slc2a9

solute carrier family 2 (facilitated glucose transporter), member 9

chr4_-_149099802 0.140 ENSMUST00000103217.4
Pex14
peroxisomal biogenesis factor 14
chr15_+_83100201 0.140 ENSMUST00000078218.4
Serhl
serine hydrolase-like
chr11_-_93968242 0.136 ENSMUST00000107844.2
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr5_-_38502107 0.135 ENSMUST00000005238.6
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr6_+_134981998 0.133 ENSMUST00000167323.1
Apold1
apolipoprotein L domain containing 1
chr16_-_11909398 0.131 ENSMUST00000127972.1
ENSMUST00000121750.1
ENSMUST00000096272.4
ENSMUST00000073371.6
Cpped1



calcineurin-like phosphoesterase domain containing 1



chr15_+_83100281 0.129 ENSMUST00000167389.1
ENSMUST00000166427.1
Serhl

serine hydrolase-like

chr7_+_75455534 0.126 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr10_+_93641041 0.126 ENSMUST00000020204.4
Ntn4
netrin 4
chr19_-_10604258 0.126 ENSMUST00000037678.6
Dak
dihydroxyacetone kinase 2 homolog (yeast)
chr13_-_98815408 0.125 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr4_+_132351768 0.119 ENSMUST00000172202.1
Gm17300
predicted gene, 17300
chrX_-_37191160 0.118 ENSMUST00000016571.7
Ndufa1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chrX_+_74254782 0.116 ENSMUST00000119197.1
ENSMUST00000088313.4
Emd

emerin

chr11_+_87582201 0.113 ENSMUST00000133202.1
Sept4
septin 4
chr9_-_26999491 0.113 ENSMUST00000060513.7
ENSMUST00000120367.1
Acad8

acyl-Coenzyme A dehydrogenase family, member 8

chr5_-_30073554 0.113 ENSMUST00000026846.6
Tyms
thymidylate synthase
chr9_+_61373219 0.109 ENSMUST00000162583.1
ENSMUST00000161993.1
ENSMUST00000160882.1
ENSMUST00000160724.1
ENSMUST00000162973.1
ENSMUST00000159050.1
Tle3





transducin-like enhancer of split 3, homolog of Drosophila E(spl)





chr11_+_88204396 0.105 ENSMUST00000118784.1
ENSMUST00000139170.1
ENSMUST00000107915.3
ENSMUST00000144070.1
Mrps23



mitochondrial ribosomal protein S23



chr11_+_87760533 0.098 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr1_-_79858627 0.097 ENSMUST00000027467.4
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr7_+_64392645 0.091 ENSMUST00000037205.8
Mcee
methylmalonyl CoA epimerase
chr8_-_84893887 0.090 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
Gcdh



glutaryl-Coenzyme A dehydrogenase



chr18_+_80253274 0.088 ENSMUST00000131780.1
ENSMUST00000157056.1
Pqlc1

PQ loop repeat containing 1

chr8_-_22185758 0.087 ENSMUST00000046916.7
Ckap2
cytoskeleton associated protein 2
chr5_-_138272786 0.085 ENSMUST00000161279.1
ENSMUST00000161647.1
Gal3st4

galactose-3-O-sulfotransferase 4

chr16_+_91391721 0.084 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr7_-_19458494 0.081 ENSMUST00000085715.5
Mark4
MAP/microtubule affinity-regulating kinase 4
chr12_-_81532840 0.076 ENSMUST00000166664.1
ENSMUST00000164386.1
ENSMUST00000169158.1
ENSMUST00000164431.1
ENSMUST00000163402.1
Gm20498

Synj2bp


predicted gene 20498

synaptojanin 2 binding protein


chr19_-_5510467 0.071 ENSMUST00000070172.4
Snx32
sorting nexin 32
chr1_+_88103229 0.068 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr3_-_90389884 0.067 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr9_+_72438519 0.066 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr7_+_5034118 0.066 ENSMUST00000076791.3
4632433K11Rik
RIKEN cDNA 4632433K11 gene
chr5_+_114707760 0.063 ENSMUST00000094441.4
Tchp
trichoplein, keratin filament binding
chr2_+_91265252 0.062 ENSMUST00000028691.6
Arfgap2
ADP-ribosylation factor GTPase activating protein 2
chr11_-_32267547 0.061 ENSMUST00000109389.2
ENSMUST00000129010.1
ENSMUST00000020530.5
Nprl3


nitrogen permease regulator-like 3


chr7_-_98309471 0.059 ENSMUST00000033020.7
Acer3
alkaline ceramidase 3
chr13_+_21754067 0.055 ENSMUST00000091709.2
Hist1h2bn
histone cluster 1, H2bn
chr19_+_4097392 0.053 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr19_+_4855129 0.052 ENSMUST00000119694.1
Ctsf
cathepsin F
chr6_+_128438757 0.051 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr8_-_91133942 0.049 ENSMUST00000120213.1
ENSMUST00000109609.2
Aktip

thymoma viral proto-oncogene 1 interacting protein

chr16_+_20717665 0.049 ENSMUST00000021405.7
Polr2h
polymerase (RNA) II (DNA directed) polypeptide H
chr16_+_20651652 0.049 ENSMUST00000007212.8
Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr2_+_180078623 0.049 ENSMUST00000087563.6
Mtg2
mitochondrial ribosome associated GTPase 2
chr11_+_52360824 0.045 ENSMUST00000102758.1
Vdac1
voltage-dependent anion channel 1
chr17_+_27685197 0.045 ENSMUST00000097360.2
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chrX_-_38635066 0.044 ENSMUST00000058265.7
C1galt1c1
C1GALT1-specific chaperone 1
chr11_+_78037959 0.038 ENSMUST00000073660.6
Flot2
flotillin 2
chr2_-_17731035 0.036 ENSMUST00000028080.5
Nebl
nebulette
chr3_+_79885930 0.034 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr16_-_59632520 0.031 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr7_+_24399606 0.030 ENSMUST00000002280.4
Smg9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr11_-_93968293 0.028 ENSMUST00000170303.1
Gm20390
predicted gene 20390
chr7_+_19851994 0.028 ENSMUST00000172815.1
Gm19345
predicted gene, 19345
chr14_-_20496780 0.027 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr19_-_4793851 0.026 ENSMUST00000178615.1
ENSMUST00000179189.1
ENSMUST00000164376.2
ENSMUST00000164209.2
ENSMUST00000180248.1
Rbm4




RNA binding motif protein 4




chr5_-_138272733 0.025 ENSMUST00000161665.1
ENSMUST00000100530.1
Gal3st4

galactose-3-O-sulfotransferase 4

chr13_-_27582168 0.024 ENSMUST00000006664.1
ENSMUST00000095926.1
Prl8a1

prolactin family 8, subfamily a, member 1

chr14_-_59365410 0.023 ENSMUST00000161031.1
ENSMUST00000160425.1
Phf11d

PHD finger protein 11D

chrX_+_136822781 0.017 ENSMUST00000113085.1
Plp1
proteolipid protein (myelin) 1
chr7_-_28962265 0.017 ENSMUST00000068045.7
Actn4
actinin alpha 4
chr11_+_58948890 0.016 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr4_-_9643638 0.015 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
Asph




aspartate-beta-hydroxylase




chr9_+_45138437 0.014 ENSMUST00000060125.5
Scn4b
sodium channel, type IV, beta
chr7_+_24399921 0.013 ENSMUST00000108434.1
Smg9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr1_+_161969284 0.012 ENSMUST00000160881.1
ENSMUST00000159648.1
Pigc

phosphatidylinositol glycan anchor biosynthesis, class C

chr8_-_91134027 0.009 ENSMUST00000125257.1
Aktip
thymoma viral proto-oncogene 1 interacting protein
chrX_+_136822671 0.007 ENSMUST00000033800.6
Plp1
proteolipid protein (myelin) 1
chr4_+_115057683 0.000 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr11_-_116168138 0.000 ENSMUST00000139020.1
ENSMUST00000103031.1
ENSMUST00000124828.1
Fbf1


Fas (TNFRSF6) binding factor 1


chr1_+_51289106 0.000 ENSMUST00000051572.6
Sdpr
serum deprivation response

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.4 1.6 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.2 1.0 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.2 1.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 0.7 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.2 0.6 GO:0070488 neutrophil aggregation(GO:0070488)
0.2 2.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.2 0.6 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.6 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 0.4 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.7 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.1 1.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.2 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.1 0.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.1 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0046078 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) dUMP metabolic process(GO:0046078)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 2.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.0 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.7 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.0 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0031262 Ndc80 complex(GO:0031262)
0.3 1.2 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 1.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.2 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 0.6 GO:0032052 bile acid binding(GO:0032052)
0.2 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.4 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 1.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0050786 arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786)
0.1 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.4 GO:0008494 translation activator activity(GO:0008494)
0.1 1.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 1.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)