Motif ID: Trp73

Z-value: 0.713


Transcription factors associated with Trp73:

Gene SymbolEntrez IDGene Name
Trp73 ENSMUSG00000029026.10 Trp73

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp73mm10_v2_chr4_-_154097105_1540971730.039.1e-01Click!


Activity profile for motif Trp73.

activity profile for motif Trp73


Sorted Z-values histogram for motif Trp73

Sorted Z-values for motif Trp73



Network of associatons between targets according to the STRING database.



First level regulatory network of Trp73

PNG image of the network

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Top targets:


Showing 1 to 20 of 79 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_153665274 2.241 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr2_-_164857542 1.584 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chr9_-_58158498 1.393 ENSMUST00000168864.2
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr2_-_164857671 1.245 ENSMUST00000059954.7
 Pltp
phospholipid transfer protein
chr1_+_135729147 1.195 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr9_-_58313189 1.148 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr7_-_116038734 0.891 ENSMUST00000166877.1
 Sox6
SRY-box containing gene 6
chr7_-_31054815 0.742 ENSMUST00000071697.4
ENSMUST00000108110.3
 Fxyd1

FXYD domain-containing ion transport regulator 1

chr4_+_119232896 0.623 ENSMUST00000121111.2
ENSMUST00000030393.6
ENSMUST00000102662.4
 Lepre1


leprecan 1


chr12_-_45074112 0.569 ENSMUST00000120531.1
ENSMUST00000143376.1
 Stxbp6

syntaxin binding protein 6 (amisyn)

chr10_+_110745433 0.537 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
 E2f7



E2F transcription factor 7



chr11_-_103344651 0.534 ENSMUST00000041385.7
 Arhgap27
Rho GTPase activating protein 27
chr11_-_102230091 0.503 ENSMUST00000008999.5
 Hdac5
histone deacetylase 5
chr15_+_84232030 0.491 ENSMUST00000023072.6
 Parvb
parvin, beta
chr13_+_12702362 0.460 ENSMUST00000104944.2
 Gm2399
predicted gene 2399
chr10_+_127642975 0.451 ENSMUST00000092074.5
ENSMUST00000120279.1
 Stat6

signal transducer and activator of transcription 6

chr11_-_102230127 0.420 ENSMUST00000107150.1
ENSMUST00000156337.1
ENSMUST00000107151.2
ENSMUST00000107152.2
 Hdac5



histone deacetylase 5



chr3_+_159839729 0.412 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chr7_-_141443314 0.406 ENSMUST00000106005.2
 Lrdd
leucine-rich and death domain containing
chr11_-_69948145 0.395 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
 Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.8 GO:0042360 vitamin E metabolic process(GO:0042360)
0.2 2.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 1.0 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.9 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 0.7 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.2 0.5 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 0.5 GO:0002295 T-helper cell lineage commitment(GO:0002295) interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.4 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.3 GO:0043206 extracellular fibril organization(GO:0043206)
0.0 0.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)

Gene overrepresentation in molecular_function category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 1.1 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.1 0.9 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.4 GO:0005118 sevenless binding(GO:0005118)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)