Motif ID: Twist1
Z-value: 0.813
Transcription factors associated with Twist1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Twist1 | ENSMUSG00000035799.5 | Twist1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Twist1 | mm10_v2_chr12_+_33957645_33957671 | -0.09 | 7.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.9 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
0.3 | 0.8 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
0.2 | 2.9 | GO:0048484 | enteric nervous system development(GO:0048484) |
0.2 | 0.9 | GO:0051311 | spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311) |
0.2 | 0.8 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
0.2 | 0.8 | GO:0021508 | floor plate formation(GO:0021508) spinal cord ventral commissure morphogenesis(GO:0021965) floor plate morphogenesis(GO:0033505) |
0.1 | 1.0 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.1 | 0.4 | GO:0003096 | renal sodium ion transport(GO:0003096) |
0.1 | 1.3 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.1 | 1.2 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
0.1 | 0.4 | GO:0060023 | soft palate development(GO:0060023) |
0.1 | 0.2 | GO:1900369 | negative regulation of RNA interference(GO:1900369) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173) |
0.1 | 0.2 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) negative regulation of dopaminergic neuron differentiation(GO:1904339) regulation of cardiac cell fate specification(GO:2000043) |
0.1 | 0.4 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.1 | 0.9 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.1 | 0.7 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
0.0 | 0.2 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
0.0 | 0.3 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.0 | 0.8 | GO:0048368 | lateral mesoderm development(GO:0048368) |
0.0 | 0.6 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
0.0 | 0.4 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
0.0 | 0.4 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.0 | 0.3 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
0.0 | 0.3 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
0.0 | 0.1 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
0.0 | 0.3 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
0.0 | 0.1 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
0.0 | 0.1 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
0.0 | 0.3 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 2.6 | GO:0006836 | neurotransmitter transport(GO:0006836) |
0.0 | 0.1 | GO:0002756 | MyD88-independent toll-like receptor signaling pathway(GO:0002756) |
0.0 | 0.2 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.0 | 0.3 | GO:0032402 | melanosome transport(GO:0032402) |
0.0 | 1.6 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
0.0 | 0.1 | GO:0030836 | positive regulation of actin filament depolymerization(GO:0030836) |
0.0 | 0.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.1 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.0 | 0.2 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.2 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
0.2 | 0.5 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
0.1 | 0.6 | GO:0043293 | apoptosome(GO:0043293) |
0.1 | 0.8 | GO:0001520 | outer dense fiber(GO:0001520) |
0.1 | 0.9 | GO:0072687 | meiotic spindle(GO:0072687) |
0.1 | 0.3 | GO:0043259 | laminin-10 complex(GO:0043259) |
0.1 | 0.8 | GO:0031512 | motile primary cilium(GO:0031512) |
0.1 | 3.3 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.4 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 0.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.0 | 2.6 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.3 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 1.6 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 2.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.5 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.1 | 1.2 | GO:0034943 | acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409) |
0.1 | 1.0 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.1 | 0.2 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.0 | 3.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.3 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.0 | 0.9 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.8 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.0 | 1.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.8 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.3 | GO:0005536 | glucose binding(GO:0005536) |
0.0 | 0.3 | GO:0008758 | thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606) |
0.0 | 0.4 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.0 | 0.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.1 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.0 | 0.4 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.0 | 0.2 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.0 | 0.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |