Motif ID: Vsx2_Dlx3

Z-value: 0.611

Transcription factors associated with Vsx2_Dlx3:

Gene SymbolEntrez IDGene Name
Dlx3 ENSMUSG00000001510.7 Dlx3
Vsx2 ENSMUSG00000021239.6 Vsx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Vsx2mm10_v2_chr12_+_84569762_845698400.293.2e-01Click!


Activity profile for motif Vsx2_Dlx3.

activity profile for motif Vsx2_Dlx3


Sorted Z-values histogram for motif Vsx2_Dlx3

Sorted Z-values for motif Vsx2_Dlx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Vsx2_Dlx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 119 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_116067213 1.926 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr2_-_116067391 1.917 ENSMUST00000140185.1
 2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr18_+_57468478 1.859 ENSMUST00000091892.2
 Ctxn3
cortexin 3
chr2_+_71528657 1.713 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr1_-_190170671 1.575 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr18_-_80986578 1.354 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)
chr15_-_11037968 1.328 ENSMUST00000058007.5
 Rxfp3
relaxin family peptide receptor 3
chr16_+_42907563 1.291 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr6_+_30541582 1.206 ENSMUST00000096066.4
 Cpa2
carboxypeptidase A2, pancreatic
chr5_-_62766153 1.164 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrM_+_7005 1.101 ENSMUST00000082405.1
 mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr12_+_38780284 1.023 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr2_-_79456750 1.011 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr3_+_5218546 0.971 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr16_+_43503607 0.962 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
 Zbtb20


zinc finger and BTB domain containing 20


chr10_+_73821857 0.863 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
 Pcdh15



















protocadherin 15



















chr14_+_99298652 0.837 ENSMUST00000005279.6
 Klf5
Kruppel-like factor 5
chr1_-_140183283 0.809 ENSMUST00000111977.1
 Cfh
complement component factor h
chr1_-_140183404 0.801 ENSMUST00000066859.6
ENSMUST00000111976.2
 Cfh

complement component factor h

chr6_-_147264124 0.800 ENSMUST00000052296.6
 Pthlh
parathyroid hormone-like peptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.6 1.7 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.5 1.6 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.3 1.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.1 GO:0022900 electron transport chain(GO:0022900)
0.3 1.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)
0.1 0.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.8 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.6 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 0.5 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 GO:0072562 blood microparticle(GO:0072562)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 1.6 GO:0001851 complement component C3b binding(GO:0001851)
0.2 1.6 GO:0050693 LBD domain binding(GO:0050693)
0.0 1.3 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.1 0.8 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0004601 peroxidase activity(GO:0004601)