Motif ID: Yy1_Yy2

Z-value: 3.685

Transcription factors associated with Yy1_Yy2:

Gene SymbolEntrez IDGene Name
Yy1 ENSMUSG00000021264.11 Yy1
Yy2 ENSMUSG00000091736.2 Yy2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Yy2mm10_v2_chrX_-_157598642_157598655-0.923.3e-06Click!
Yy1mm10_v2_chr12_+_108792946_108792988-0.391.7e-01Click!


Activity profile for motif Yy1_Yy2.

activity profile for motif Yy1_Yy2


Sorted Z-values histogram for motif Yy1_Yy2

Sorted Z-values for motif Yy1_Yy2



Network of associatons between targets according to the STRING database.



First level regulatory network of Yy1_Yy2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 5.660 ENSMUST00000075312.3
 Ttr
transthyretin
chr19_-_50030735 5.066 ENSMUST00000071866.1
 Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr3_-_90213577 4.754 ENSMUST00000170122.2
 Rps27
ribosomal protein S27
chr17_-_23829095 3.960 ENSMUST00000069579.5
 Tceb2
transcription elongation factor B (SIII), polypeptide 2
chr7_+_35802593 3.411 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr3_-_130730375 3.349 ENSMUST00000079085.6
 Rpl34
ribosomal protein L34
chr19_-_59170978 3.283 ENSMUST00000172821.2
 Vax1
ventral anterior homeobox containing gene 1
chr14_-_54617993 2.841 ENSMUST00000022803.4
 Psmb5
proteasome (prosome, macropain) subunit, beta type 5
chr10_+_79669410 2.800 ENSMUST00000020552.5
 Tpgs1
tubulin polyglutamylase complex subunit 1
chr3_-_130730310 2.793 ENSMUST00000062601.7
 Rpl34
ribosomal protein L34
chr10_-_128549102 2.763 ENSMUST00000176906.1
 Rpl41
ribosomal protein L41
chr18_+_74216118 2.741 ENSMUST00000025444.6
 Cxxc1
CXXC finger 1 (PHD domain)
chr10_-_128549125 2.717 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
 Rpl41


ribosomal protein L41


chr7_+_25659153 2.675 ENSMUST00000079634.6
 Exosc5
exosome component 5
chr1_+_42697146 2.633 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr16_+_33056453 2.607 ENSMUST00000078804.5
ENSMUST00000115079.1
 Rpl35a

ribosomal protein L35A

chr12_-_4592927 2.597 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr16_+_33056499 2.550 ENSMUST00000115078.1
 Rpl35a
ribosomal protein L35A
chr11_+_75732869 2.501 ENSMUST00000067664.3
 Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr17_+_34031787 2.423 ENSMUST00000044858.8
 Rxrb
retinoid X receptor beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 893 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 18.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.7 15.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 13.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 12.3 GO:0006412 translation(GO:0006412)
0.4 10.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 9.3 GO:0042254 ribosome biogenesis(GO:0042254)
0.2 8.2 GO:0032543 mitochondrial translation(GO:0032543)
1.2 5.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 5.8 GO:0001893 maternal placenta development(GO:0001893)
0.4 5.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.4 5.6 GO:0043248 proteasome assembly(GO:0043248)
0.4 5.3 GO:0000338 protein deneddylation(GO:0000338)
0.3 5.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.8 4.8 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.5 4.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 4.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 4.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.9 4.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.3 4.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 4.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 326 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 52.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 46.1 GO:0005739 mitochondrion(GO:0005739)
0.1 39.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.7 33.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.5 23.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 10.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.5 9.6 GO:0005839 proteasome core complex(GO:0005839)
0.2 9.3 GO:0015934 large ribosomal subunit(GO:0015934)
0.6 7.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 6.7 GO:0072562 blood microparticle(GO:0072562)
0.6 6.5 GO:0031931 TORC1 complex(GO:0031931)
1.4 5.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 4.9 GO:0008180 COP9 signalosome(GO:0008180)
0.9 4.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.3 4.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 4.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.5 4.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 4.2 GO:0000786 nucleosome(GO:0000786)
0.6 3.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
1.3 3.8 GO:0070449 elongin complex(GO:0070449)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 546 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 100.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 12.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.4 9.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 6.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 6.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.8 6.1 GO:0070324 thyroid hormone binding(GO:0070324)
1.4 5.7 GO:0031720 haptoglobin binding(GO:0031720)
0.2 5.5 GO:0019843 rRNA binding(GO:0019843)
0.5 5.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.9 5.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 5.1 GO:0050815 phosphoserine binding(GO:0050815)
0.3 5.1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.1 5.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 4.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 4.5 GO:0071837 HMG box domain binding(GO:0071837)
0.1 4.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 4.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.3 4.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 4.0 GO:0016805 dipeptidase activity(GO:0016805)
0.1 4.0 GO:0031492 nucleosomal DNA binding(GO:0031492)