Motif ID: Zbtb12

Z-value: 0.351


Transcription factors associated with Zbtb12:

Gene SymbolEntrez IDGene Name
Zbtb12 ENSMUSG00000049823.8 Zbtb12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb12mm10_v2_chr17_+_34894515_348945730.332.5e-01Click!


Activity profile for motif Zbtb12.

activity profile for motif Zbtb12


Sorted Z-values histogram for motif Zbtb12

Sorted Z-values for motif Zbtb12



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb12

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_37367354 0.430 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr3_-_84155762 0.417 ENSMUST00000047368.6
 Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr3_+_5218546 0.336 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr3_+_5218516 0.317 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr3_+_5218589 0.230 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr11_+_54902917 0.177 ENSMUST00000149324.1
 Gpx3
glutathione peroxidase 3
chr15_+_102503722 0.160 ENSMUST00000096145.4
 Gm10337
predicted gene 10337
chr3_-_131344892 0.160 ENSMUST00000090246.4
ENSMUST00000126569.1
 Sgms2

sphingomyelin synthase 2

chr10_-_86011833 0.149 ENSMUST00000105304.1
ENSMUST00000061699.5
 Bpifc

BPI fold containing family C

chr4_-_45489794 0.144 ENSMUST00000146236.1
 Shb
src homology 2 domain-containing transforming protein B
chr3_+_88081997 0.137 ENSMUST00000071812.5
 Iqgap3
IQ motif containing GTPase activating protein 3
chr15_+_82341179 0.135 ENSMUST00000050349.2
 Fam109b
family with sequence similarity 109, member B
chr7_-_25477607 0.118 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
 Ceacam1


carcinoembryonic antigen-related cell adhesion molecule 1


chr5_-_35679416 0.117 ENSMUST00000114233.2
 Htra3
HtrA serine peptidase 3
chr8_-_45382198 0.113 ENSMUST00000093526.6
 Fam149a
family with sequence similarity 149, member A
chr4_-_151057933 0.109 ENSMUST00000030797.3
 Vamp3
vesicle-associated membrane protein 3
chr4_+_119539716 0.106 ENSMUST00000137560.1
 Foxj3
forkhead box J3
chr14_-_103844173 0.102 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr9_+_22411515 0.099 ENSMUST00000058868.7
 9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr5_+_92603039 0.096 ENSMUST00000050952.3
 Stbd1
starch binding domain 1
chr6_+_90462562 0.094 ENSMUST00000032174.5
 Klf15
Kruppel-like factor 15
chr2_-_28916668 0.088 ENSMUST00000113847.1
 Barhl1
BarH-like 1 (Drosophila)
chr2_+_31759993 0.083 ENSMUST00000124089.1
 Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr7_-_141918481 0.078 ENSMUST00000151890.1
 Tollip
toll interacting protein
chr11_-_12027958 0.077 ENSMUST00000109654.1
 Grb10
growth factor receptor bound protein 10
chr4_+_32983417 0.075 ENSMUST00000084747.5
 Rragd
Ras-related GTP binding D
chr6_+_29398920 0.070 ENSMUST00000181464.1
ENSMUST00000180829.1
 Ccdc136

coiled-coil domain containing 136

chr5_+_30281377 0.068 ENSMUST00000101448.3
 Drc1
dynein regulatory complex subunit 1
chrX_+_94724569 0.065 ENSMUST00000101388.2
 Zxdb
zinc finger, X-linked, duplicated B
chr18_+_60526194 0.064 ENSMUST00000025505.5
 Dctn4
dynactin 4
chr17_-_27029009 0.063 ENSMUST00000078691.5
 Bak1
BCL2-antagonist/killer 1
chr2_+_30364262 0.062 ENSMUST00000142801.1
ENSMUST00000100214.3
 Fam73b

family with sequence similarity 73, member B

chr5_-_24447587 0.059 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
 Tmub1



transmembrane and ubiquitin-like domain containing 1



chr2_+_30364227 0.051 ENSMUST00000077977.7
ENSMUST00000140075.2
 Fam73b

family with sequence similarity 73, member B

chr19_-_10240689 0.050 ENSMUST00000088013.5
 Myrf
myelin regulatory factor
chr4_-_41723129 0.045 ENSMUST00000171641.1
ENSMUST00000030158.4
 Dctn3

dynactin 3

chr17_-_27909206 0.042 ENSMUST00000114848.1
 Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_-_70592782 0.041 ENSMUST00000162251.1
 Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr16_-_33967032 0.040 ENSMUST00000023510.6
 Umps
uridine monophosphate synthetase
chr2_+_31759932 0.039 ENSMUST00000028190.6
 Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr7_+_126976338 0.039 ENSMUST00000032920.3
 Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr11_-_100441795 0.039 ENSMUST00000107398.1
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr3_-_130061553 0.031 ENSMUST00000168675.1
 Sec24b
Sec24 related gene family, member B (S. cerevisiae)
chr11_+_98446826 0.030 ENSMUST00000019456.4
 Grb7
growth factor receptor bound protein 7
chr19_-_6080311 0.029 ENSMUST00000159832.1
 Vps51
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr19_+_46573362 0.027 ENSMUST00000026011.6
 Sfxn2
sideroflexin 2
chr8_-_69774884 0.027 ENSMUST00000137573.1
ENSMUST00000149782.1
 Zfp866
Gm20422
zinc finger protein 866
predicted gene 20422
chr4_-_133633419 0.023 ENSMUST00000084238.4
 Zdhhc18
zinc finger, DHHC domain containing 18
chr6_-_118757974 0.020 ENSMUST00000112825.2
 Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr11_+_54902743 0.020 ENSMUST00000082430.3
 Gpx3
glutathione peroxidase 3
chr16_+_55966275 0.019 ENSMUST00000023269.4
 RPL24
60S ribosomal protein L24
chr7_+_92875253 0.014 ENSMUST00000076052.6
 Prcp
prolylcarboxypeptidase (angiotensinase C)
chr11_-_3409162 0.010 ENSMUST00000101638.3
 Limk2
LIM motif-containing protein kinase 2
chr19_-_40402267 0.007 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
 Sorbs1



sorbin and SH3 domain containing 1



chr17_+_83350925 0.005 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
 Eml4


echinoderm microtubule associated protein like 4


chr15_-_79546741 0.004 ENSMUST00000054014.7
 Ddx17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr17_+_27909337 0.003 ENSMUST00000114842.1
ENSMUST00000025058.7
ENSMUST00000088027.5
 Anks1


ankyrin repeat and SAM domain containing 1


chr9_-_78481724 0.003 ENSMUST00000042235.8
 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr11_+_49247462 0.002 ENSMUST00000109194.1
 Mgat1
mannoside acetylglucosaminyltransferase 1
chr17_-_15375969 0.002 ENSMUST00000014917.7
 Dll1
delta-like 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.0 0.1 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.0 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.0 0.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)