Motif ID: Zbtb16
Z-value: 1.348
Transcription factors associated with Zbtb16:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zbtb16 | ENSMUSG00000066687.4 | Zbtb16 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb16 | mm10_v2_chr9_-_48835932_48835962 | -0.63 | 1.6e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.4 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.8 | 3.0 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
| 0.7 | 2.1 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.7 | 2.0 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
| 0.4 | 2.2 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.4 | 2.9 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.4 | 2.7 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.4 | 1.1 | GO:1905065 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 0.3 | 1.3 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.3 | 2.2 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
| 0.3 | 16.8 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.2 | 1.2 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.2 | 1.1 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.2 | 2.1 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.2 | 0.6 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
| 0.2 | 0.6 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
| 0.2 | 0.6 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
| 0.2 | 0.6 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.2 | 0.8 | GO:0072592 | regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
| 0.2 | 0.6 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
| 0.2 | 0.8 | GO:0036337 | Fas signaling pathway(GO:0036337) |
| 0.2 | 1.2 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.1 | 1.3 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.1 | 1.4 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.1 | 0.8 | GO:0002317 | plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.1 | 0.7 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.1 | 1.8 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.1 | 0.4 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.1 | 0.5 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.1 | 0.6 | GO:0051461 | regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.1 | 0.4 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 0.1 | 1.2 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.1 | 0.5 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) negative regulation of ubiquitin protein ligase activity(GO:1904667) |
| 0.1 | 0.4 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.1 | 0.5 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.1 | 1.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.1 | 0.4 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.1 | 0.9 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.1 | 0.6 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
| 0.1 | 1.5 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
| 0.1 | 0.2 | GO:0006203 | dGTP catabolic process(GO:0006203) |
| 0.1 | 1.4 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 0.3 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.0 | 0.5 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.0 | 0.2 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.0 | 2.2 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.0 | 3.0 | GO:0050852 | T cell receptor signaling pathway(GO:0050852) |
| 0.0 | 1.3 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.0 | 0.2 | GO:0002024 | diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845) |
| 0.0 | 1.0 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.0 | 1.8 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 0.2 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.0 | 0.2 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 0.4 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 1.0 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.5 | GO:0032042 | mitochondrial DNA metabolic process(GO:0032042) |
| 0.0 | 0.2 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
| 0.0 | 0.1 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.0 | 2.7 | GO:0016052 | carbohydrate catabolic process(GO:0016052) |
| 0.0 | 0.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 0.2 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.0 | 0.3 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 0.9 | GO:0045843 | negative regulation of striated muscle tissue development(GO:0045843) |
| 0.0 | 0.1 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.0 | 0.3 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.0 | 1.4 | GO:0042472 | inner ear morphogenesis(GO:0042472) |
| 0.0 | 0.5 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 0.6 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.3 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.0 | 0.1 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.0 | 0.4 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
| 0.0 | 0.3 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.1 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.2 | GO:0007097 | nuclear migration(GO:0007097) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.0 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.5 | 2.4 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.4 | 2.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.3 | 1.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.2 | 0.6 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 0.2 | 1.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.2 | 0.5 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.1 | 0.6 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.1 | 0.4 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.1 | 0.4 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.1 | 0.3 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.1 | 0.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.1 | 0.7 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.1 | 0.6 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.1 | 1.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 0.3 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.6 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 0.9 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.3 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 1.2 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 2.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.5 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 0.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 0.2 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 2.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.1 | GO:0044754 | amphisome(GO:0044753) autolysosome(GO:0044754) |
| 0.0 | 0.6 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 2.2 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.6 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 1.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 1.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.2 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.0 | 0.1 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.0 | 0.8 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.5 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 2.9 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.7 | 2.2 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 0.5 | 2.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.5 | 1.5 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.5 | 1.4 | GO:0003977 | UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977) |
| 0.3 | 2.4 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.3 | 1.3 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.2 | 1.8 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.2 | 0.6 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.2 | 2.9 | GO:0008430 | selenium binding(GO:0008430) |
| 0.2 | 1.2 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.2 | 2.1 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.2 | 3.0 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.2 | 0.6 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.2 | 0.5 | GO:0030519 | snoRNP binding(GO:0030519) |
| 0.2 | 2.0 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.1 | 1.1 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 1.8 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.1 | 0.8 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.1 | 1.4 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
| 0.1 | 0.6 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 0.9 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 0.4 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 0.4 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.1 | 1.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 0.5 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.1 | 0.6 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 1.0 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.1 | 1.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 2.2 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 1.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 1.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.6 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 2.1 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 0.2 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.0 | 1.0 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.0 | 0.5 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.0 | 0.6 | GO:0016594 | glycine binding(GO:0016594) |
| 0.0 | 0.5 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
| 0.0 | 1.3 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.2 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.0 | 1.4 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 0.4 | GO:0016208 | AMP binding(GO:0016208) |
| 0.0 | 0.7 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.8 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.2 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.0 | 0.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 0.2 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 0.0 | 0.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 2.6 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.1 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.0 | 0.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.2 | GO:0008413 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) |
| 0.0 | 0.3 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.3 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.3 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
