Motif ID: Zbtb18

Z-value: 1.033


Transcription factors associated with Zbtb18:

Gene SymbolEntrez IDGene Name
Zbtb18 ENSMUSG00000063659.6 Zbtb18

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb18mm10_v2_chr1_+_177444653_177444669-0.431.2e-01Click!


Activity profile for motif Zbtb18.

activity profile for motif Zbtb18


Sorted Z-values histogram for motif Zbtb18

Sorted Z-values for motif Zbtb18



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb18

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 4.154 ENSMUST00000075312.3
 Ttr
transthyretin
chr1_+_45311538 2.974 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chrY_+_897782 1.927 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr7_-_19699008 1.863 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
 Apoe





apolipoprotein E





chr4_-_136898803 1.542 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr10_+_127514939 1.466 ENSMUST00000035735.9
 Ndufa4l2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_-_171059390 1.214 ENSMUST00000164044.1
ENSMUST00000169017.1
 Fcgr3

Fc receptor, IgG, low affinity III

chr5_+_112255813 1.037 ENSMUST00000031286.6
ENSMUST00000131673.1
ENSMUST00000112375.1
 Crybb1


crystallin, beta B1


chr1_-_162866502 0.997 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr12_+_103434211 0.940 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
 Ifi27





interferon, alpha-inducible protein 27





chr4_+_130915949 0.901 ENSMUST00000030316.6
 Laptm5
lysosomal-associated protein transmembrane 5
chr5_-_137072254 0.872 ENSMUST00000077523.3
ENSMUST00000041388.4
 Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr6_+_7555053 0.871 ENSMUST00000090679.2
ENSMUST00000184986.1
 Tac1

tachykinin 1

chr17_-_35027909 0.811 ENSMUST00000040151.2
 Sapcd1
suppressor APC domain containing 1
chr9_-_48911067 0.793 ENSMUST00000003826.7
 Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr15_+_78926720 0.763 ENSMUST00000089377.5
 Lgals1
lectin, galactose binding, soluble 1
chr6_+_135362931 0.746 ENSMUST00000032330.9
 Emp1
epithelial membrane protein 1
chr9_-_103219823 0.734 ENSMUST00000168142.1
 Trf
transferrin
chr7_-_99695809 0.689 ENSMUST00000107086.2
 Slco2b1
solute carrier organic anion transporter family, member 2b1
chr2_-_26516620 0.659 ENSMUST00000132820.1
 Notch1
notch 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.6 3.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 1.9 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.4 1.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 1.2 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.4 1.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 1.1 GO:0032060 bleb assembly(GO:0032060)
0.1 1.0 GO:0009404 toxin metabolic process(GO:0009404)
0.0 1.0 GO:0007601 visual perception(GO:0007601)
0.3 0.9 GO:0010757 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) negative regulation of plasminogen activation(GO:0010757) regulation of vascular wound healing(GO:0061043) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 0.9 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.0 0.9 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.3 0.8 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.2 0.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.8 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2 0.7 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.7 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 1.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.9 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) dense body(GO:0097433)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)
0.2 0.5 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0032009 early phagosome(GO:0032009)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:1990423 RZZ complex(GO:1990423)
0.1 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.3 GO:0043218 compact myelin(GO:0043218)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 3.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.6 1.9 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 1.9 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.4 1.2 GO:0019770 IgG receptor activity(GO:0019770)
0.4 1.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 1.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 0.8 GO:0005534 galactose binding(GO:0005534)
0.2 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.1 0.7 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)