Motif ID: Zbtb3

Z-value: 0.664


Transcription factors associated with Zbtb3:

Gene SymbolEntrez IDGene Name
Zbtb3 ENSMUSG00000071661.6 Zbtb3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb3mm10_v2_chr19_+_8802486_88025300.048.9e-01Click!


Activity profile for motif Zbtb3.

activity profile for motif Zbtb3


Sorted Z-values histogram for motif Zbtb3

Sorted Z-values for motif Zbtb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 128 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_172043466 1.101 ENSMUST00000087950.3
 Cbln4
cerebellin 4 precursor protein
chr8_+_10272572 0.870 ENSMUST00000042103.8
 Myo16
myosin XVI
chr11_-_54028090 0.803 ENSMUST00000020586.6
 Slc22a4
solute carrier family 22 (organic cation transporter), member 4
chr15_+_76797628 0.670 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr11_-_59787636 0.647 ENSMUST00000125307.1
 Pld6
phospholipase D family, member 6
chr2_-_25627960 0.617 ENSMUST00000028307.8
 Fcna
ficolin A
chr9_-_97018823 0.601 ENSMUST00000055433.4
 Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chrX_+_53607918 0.543 ENSMUST00000114827.1
 Cxx1c
CAAX box 1C
chrX_+_53607987 0.515 ENSMUST00000063384.3
ENSMUST00000169626.1
 Cxx1c

CAAX box 1C

chr13_+_76579670 0.435 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr2_-_127792467 0.413 ENSMUST00000135091.1
 1500011K16Rik
RIKEN cDNA 1500011K16 gene
chr14_-_26067355 0.408 ENSMUST00000100819.5
 Tmem254c
transmembrane protein 254c
chr9_-_40531362 0.388 ENSMUST00000119373.1
 Gramd1b
GRAM domain containing 1B
chr19_-_58455903 0.376 ENSMUST00000131877.1
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr10_+_60346851 0.351 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
 4632428N05Rik


RIKEN cDNA 4632428N05 gene


chr16_+_20589471 0.348 ENSMUST00000100074.3
ENSMUST00000096197.4
 Vwa5b2

von Willebrand factor A domain containing 5B2

chr9_+_75625707 0.340 ENSMUST00000034702.4
 Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr8_+_114439655 0.332 ENSMUST00000004756.7
ENSMUST00000109108.2
ENSMUST00000160862.1
ENSMUST00000109107.2
 Wwox



WW domain-containing oxidoreductase



chr1_-_133921393 0.312 ENSMUST00000048432.5
 Prelp
proline arginine-rich end leucine-rich repeat
chr13_-_96132568 0.307 ENSMUST00000161263.1
 Sv2c
synaptic vesicle glycoprotein 2c

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0015879 carnitine transport(GO:0015879)
0.2 0.6 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.3 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.2 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.1 0.2 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.2 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 0.8 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.6 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030) angiostatin binding(GO:0043532)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) cobalt ion binding(GO:0050897)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)