Motif ID: Zbtb33_Chd2

Z-value: 1.980

Transcription factors associated with Zbtb33_Chd2:

Gene SymbolEntrez IDGene Name
Chd2 ENSMUSG00000078671.4 Chd2
Zbtb33 ENSMUSG00000048047.3 Zbtb33

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb33mm10_v2_chrX_+_38189780_381898260.868.8e-05Click!
Chd2mm10_v2_chr7_-_73541738_735417580.544.6e-02Click!


Activity profile for motif Zbtb33_Chd2.

activity profile for motif Zbtb33_Chd2


Sorted Z-values histogram for motif Zbtb33_Chd2

Sorted Z-values for motif Zbtb33_Chd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb33_Chd2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_105176860 2.768 ENSMUST00000163545.1
 Rbm26
RNA binding motif protein 26
chr9_+_121719403 2.697 ENSMUST00000182225.1
 Nktr
natural killer tumor recognition sequence
chrX_-_166440671 2.695 ENSMUST00000049501.8
 Ofd1
oral-facial-digital syndrome 1 gene homolog (human)
chr2_+_121867083 2.591 ENSMUST00000089912.5
ENSMUST00000089915.3
 Casc4

cancer susceptibility candidate 4

chrX_+_151803642 2.576 ENSMUST00000156616.2
 Huwe1
HECT, UBA and WWE domain containing 1
chr11_+_29172890 2.575 ENSMUST00000102856.2
ENSMUST00000020755.5
 Smek2

SMEK homolog 2, suppressor of mek1 (Dictyostelium)

chr14_-_105177280 2.522 ENSMUST00000100327.3
ENSMUST00000022715.7
 Rbm26

RNA binding motif protein 26

chr2_+_121866918 2.497 ENSMUST00000078752.3
ENSMUST00000110586.3
 Casc4

cancer susceptibility candidate 4

chr14_-_105177263 2.492 ENSMUST00000163499.1
 Rbm26
RNA binding motif protein 26
chr9_+_54863742 2.448 ENSMUST00000034843.7
 Ireb2
iron responsive element binding protein 2
chr1_+_130717320 2.447 ENSMUST00000049813.4
 Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr14_-_78536762 2.407 ENSMUST00000123853.1
 Akap11
A kinase (PRKA) anchor protein 11
chr14_-_78536854 2.213 ENSMUST00000022593.5
 Akap11
A kinase (PRKA) anchor protein 11
chr9_+_121719172 2.173 ENSMUST00000035112.6
ENSMUST00000182311.1
 Nktr

natural killer tumor recognition sequence

chr4_+_94614483 1.945 ENSMUST00000030311.4
ENSMUST00000107104.2
 Ift74

intraflagellar transport 74

chr13_+_63815240 1.895 ENSMUST00000021926.5
ENSMUST00000095724.3
ENSMUST00000143449.1
ENSMUST00000067821.5
 Ercc6l2



excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2



chrX_-_37110257 1.828 ENSMUST00000076265.6
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chrX_+_85574018 1.819 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
 Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr3_+_30792876 1.754 ENSMUST00000029256.7
 Sec62
SEC62 homolog (S. cerevisiae)
chr17_-_83631892 1.624 ENSMUST00000051482.1
 Kcng3
potassium voltage-gated channel, subfamily G, member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 4.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 4.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 3.3 GO:0006284 base-excision repair(GO:0006284)
0.0 3.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9 2.7 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 2.6 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.3 2.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.5 2.4 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.2 2.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 2.4 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.8 2.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.3 2.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 2.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 2.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.5 2.1 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.4 2.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 2.0 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.2 1.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 1.7 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 3.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.4 2.7 GO:0000796 condensin complex(GO:0000796)
0.4 2.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 2.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 2.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 2.3 GO:0005827 polar microtubule(GO:0005827)
0.1 2.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 2.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.9 GO:0016235 aggresome(GO:0016235)
0.1 1.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 1.3 GO:0001651 dense fibrillar component(GO:0001651)
0.4 1.2 GO:0005940 septin ring(GO:0005940)
0.1 1.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 1.2 GO:0044815 DNA packaging complex(GO:0044815)
0.1 1.1 GO:0016589 NURF complex(GO:0016589)
0.2 1.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.5 GO:0004386 helicase activity(GO:0004386)
0.0 6.4 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.1 4.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3 4.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 3.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 3.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.4 3.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.8 2.4 GO:0030350 iron-responsive element binding(GO:0030350)
0.5 2.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.8 2.3 GO:0031208 POZ domain binding(GO:0031208)
0.1 2.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.2 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.3 1.2 GO:0016149 translation release factor activity, codon specific(GO:0016149)