Motif ID: Zbtb4
Z-value: 1.500
Transcription factors associated with Zbtb4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zbtb4 | ENSMUSG00000018750.8 | Zbtb4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zbtb4 | mm10_v2_chr11_+_69765899_69765925 | -0.11 | 7.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 5.1 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
1.1 | 7.4 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
0.9 | 4.3 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) negative regulation of filopodium assembly(GO:0051490) |
0.8 | 6.3 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
0.7 | 8.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.5 | 2.2 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
0.5 | 2.6 | GO:0071205 | clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205) |
0.5 | 3.0 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
0.5 | 1.5 | GO:0070488 | neutrophil aggregation(GO:0070488) |
0.4 | 1.5 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
0.3 | 3.9 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.3 | 0.8 | GO:0090298 | negative regulation of mitochondrial DNA replication(GO:0090298) |
0.3 | 0.8 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.3 | 0.3 | GO:0003162 | atrioventricular node development(GO:0003162) |
0.3 | 2.0 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.2 | 0.7 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
0.2 | 0.9 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
0.2 | 0.9 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
0.2 | 1.5 | GO:0015808 | L-alanine transport(GO:0015808) |
0.2 | 1.4 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.2 | 1.3 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.2 | 1.4 | GO:0006004 | fucose metabolic process(GO:0006004) |
0.2 | 0.5 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.2 | 0.5 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
0.2 | 0.8 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.2 | 0.6 | GO:0046084 | adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084) |
0.2 | 0.9 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
0.1 | 0.4 | GO:0048352 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) |
0.1 | 0.4 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.1 | 0.5 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
0.1 | 1.1 | GO:0040016 | embryonic cleavage(GO:0040016) |
0.1 | 0.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.1 | 0.8 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.1 | 0.8 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.1 | 0.3 | GO:0014028 | notochord formation(GO:0014028) |
0.1 | 0.6 | GO:0039532 | negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) |
0.1 | 4.8 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.1 | 2.2 | GO:0008209 | androgen metabolic process(GO:0008209) |
0.1 | 0.4 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) regulation of membrane tubulation(GO:1903525) |
0.1 | 1.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 2.9 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
0.1 | 0.9 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.1 | 2.2 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.1 | 1.1 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
0.1 | 0.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
0.1 | 1.8 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.1 | 1.0 | GO:0071436 | sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436) |
0.1 | 2.0 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.1 | 0.5 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.1 | 0.5 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
0.1 | 0.2 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
0.1 | 0.6 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 1.2 | GO:0042104 | positive regulation of activated T cell proliferation(GO:0042104) |
0.1 | 0.4 | GO:0072028 | nephron morphogenesis(GO:0072028) |
0.0 | 0.1 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
0.0 | 0.5 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.0 | 0.4 | GO:0015684 | ferrous iron transport(GO:0015684) |
0.0 | 8.0 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
0.0 | 0.2 | GO:0031033 | myosin filament organization(GO:0031033) |
0.0 | 0.7 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.0 | 0.6 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
0.0 | 0.4 | GO:1901409 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.0 | 3.7 | GO:0048663 | neuron fate commitment(GO:0048663) |
0.0 | 0.2 | GO:1903912 | negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912) |
0.0 | 0.4 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
0.0 | 0.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.0 | 0.3 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.0 | 0.8 | GO:0097320 | membrane tubulation(GO:0097320) |
0.0 | 1.9 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
0.0 | 0.2 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
0.0 | 0.5 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.1 | GO:0032532 | regulation of microvillus length(GO:0032532) |
0.0 | 0.1 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.0 | 0.7 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.0 | 0.1 | GO:1903799 | negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799) |
0.0 | 0.1 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
0.0 | 1.2 | GO:0055072 | iron ion homeostasis(GO:0055072) |
0.0 | 0.4 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.0 | 0.1 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.0 | 0.3 | GO:0016926 | protein desumoylation(GO:0016926) |
0.0 | 0.2 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
0.0 | 0.6 | GO:0007566 | embryo implantation(GO:0007566) |
0.0 | 0.8 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.1 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.0 | 0.2 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.0 | 0.1 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
0.0 | 0.5 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
0.0 | 1.0 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
0.0 | 0.5 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 0.8 | GO:0030641 | regulation of cellular pH(GO:0030641) |
0.0 | 0.7 | GO:0035418 | protein localization to synapse(GO:0035418) |
0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.0 | 0.0 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.1 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
0.4 | 4.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.4 | 3.9 | GO:0043083 | synaptic cleft(GO:0043083) |
0.3 | 6.3 | GO:0000145 | exocyst(GO:0000145) |
0.2 | 8.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.2 | 1.0 | GO:0044327 | dendritic spine head(GO:0044327) |
0.2 | 2.6 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.2 | 0.8 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
0.1 | 0.5 | GO:0071942 | XPC complex(GO:0071942) |
0.1 | 1.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 0.6 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.1 | 1.6 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.1 | 0.8 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.1 | 1.1 | GO:0097470 | ribbon synapse(GO:0097470) |
0.1 | 0.5 | GO:0042587 | glycogen granule(GO:0042587) |
0.1 | 0.7 | GO:0097542 | ciliary tip(GO:0097542) |
0.1 | 1.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.5 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
0.0 | 4.3 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.8 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.0 | 0.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 0.6 | GO:0005938 | cell cortex(GO:0005938) |
0.0 | 0.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.4 | GO:0005901 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
0.0 | 2.4 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 1.3 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 1.1 | GO:0034399 | nuclear periphery(GO:0034399) |
0.0 | 0.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 0.1 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
0.0 | 0.2 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 0.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.0 | 0.5 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.5 | GO:0005771 | multivesicular body(GO:0005771) |
0.0 | 0.1 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.0 | 1.3 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
0.0 | 0.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.3 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 8.2 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
1.1 | 4.3 | GO:0070976 | calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976) |
0.7 | 2.2 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.6 | 3.9 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.5 | 1.5 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
0.5 | 3.0 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.4 | 1.5 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.4 | 1.4 | GO:0042806 | fucose binding(GO:0042806) |
0.3 | 5.1 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.3 | 6.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.3 | 2.0 | GO:0046790 | virion binding(GO:0046790) |
0.2 | 1.5 | GO:0050786 | arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786) |
0.2 | 1.3 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.2 | 0.8 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
0.2 | 1.6 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
0.2 | 5.1 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
0.2 | 2.6 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.1 | 0.9 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) |
0.1 | 1.2 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.1 | 0.4 | GO:0004568 | chitinase activity(GO:0004568) |
0.1 | 0.8 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.5 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.1 | 1.0 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
0.1 | 2.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 2.2 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
0.1 | 0.5 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 1.8 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.1 | 0.9 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.1 | 0.8 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.1 | 0.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 2.2 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.1 | 1.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.1 | 0.4 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.1 | 1.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 0.5 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.1 | 0.4 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 2.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 0.5 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.1 | 0.6 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 0.8 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.0 | 0.4 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.0 | 0.4 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.2 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.0 | 1.1 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.7 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.0 | 0.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.0 | 0.5 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 0.2 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
0.0 | 1.4 | GO:0030551 | cyclic nucleotide binding(GO:0030551) |
0.0 | 0.6 | GO:0001221 | transcription cofactor binding(GO:0001221) |
0.0 | 0.7 | GO:0042805 | actinin binding(GO:0042805) |
0.0 | 2.8 | GO:0002020 | protease binding(GO:0002020) |
0.0 | 1.9 | GO:0030792 | methylarsonite methyltransferase activity(GO:0030792) |
0.0 | 0.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.2 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.0 | 8.3 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.0 | 0.3 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.0 | 0.5 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
0.0 | 0.4 | GO:0042171 | lysophosphatidic acid acyltransferase activity(GO:0042171) |
0.0 | 0.1 | GO:0045545 | syndecan binding(GO:0045545) |
0.0 | 0.3 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.0 | 2.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.2 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.1 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.0 | 0.7 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.0 | 0.0 | GO:0009881 | photoreceptor activity(GO:0009881) |