Motif ID: Zbtb4

Z-value: 1.500


Transcription factors associated with Zbtb4:

Gene SymbolEntrez IDGene Name
Zbtb4 ENSMUSG00000018750.8 Zbtb4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb4mm10_v2_chr11_+_69765899_69765925-0.117.2e-01Click!


Activity profile for motif Zbtb4.

activity profile for motif Zbtb4


Sorted Z-values histogram for motif Zbtb4

Sorted Z-values for motif Zbtb4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_125490688 8.167 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr7_+_123982799 5.369 ENSMUST00000106437.1
Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chrX_+_164373363 4.730 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr6_+_58831456 4.660 ENSMUST00000141600.1
ENSMUST00000122981.1
Herc3

hect domain and RLD 3

chr14_-_30626196 4.305 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd


protein kinase C, delta


chr18_-_13972617 4.186 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr16_+_11984581 4.069 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chrX_+_103422010 3.638 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr6_-_48841373 3.527 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr12_-_45074112 3.473 ENSMUST00000120531.1
ENSMUST00000143376.1
Stxbp6

syntaxin binding protein 6 (amisyn)

chr6_+_58831748 3.458 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr10_+_100015817 3.012 ENSMUST00000130190.1
ENSMUST00000020129.7
Kitl

kit ligand

chr6_-_48841098 2.957 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr12_-_45074457 2.822 ENSMUST00000053768.6
Stxbp6
syntaxin binding protein 6 (amisyn)
chr6_+_47244359 2.560 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chrX_+_41401304 2.140 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr14_-_101729690 2.107 ENSMUST00000066461.3
Gm9922
predicted gene 9922
chr9_+_75071386 1.980 ENSMUST00000155282.2
Myo5a
myosin VA
chr9_+_59680144 1.880 ENSMUST00000123914.1
Gramd2
GRAM domain containing 2
chr18_-_6136057 1.869 ENSMUST00000182559.1
Arhgap12
Rho GTPase activating protein 12

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 8.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 8.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
1.1 7.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.8 6.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.3 5.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 4.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.9 4.3 GO:0006680 glucosylceramide catabolic process(GO:0006680) negative regulation of filopodium assembly(GO:0051490)
0.3 3.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 3.7 GO:0048663 neuron fate commitment(GO:0048663)
0.5 3.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 2.9 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.5 2.6 GO:0071205 clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205)
0.5 2.2 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.1 2.2 GO:0008209 androgen metabolic process(GO:0008209)
0.1 2.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.3 2.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 2.0 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 1.9 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.1 1.8 GO:0015701 bicarbonate transport(GO:0015701)
0.5 1.5 GO:0070488 neutrophil aggregation(GO:0070488)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 6.3 GO:0000145 exocyst(GO:0000145)
1.7 5.1 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.0 4.3 GO:0016363 nuclear matrix(GO:0016363)
0.4 4.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 3.9 GO:0043083 synaptic cleft(GO:0043083)
0.2 2.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 2.4 GO:0016605 PML body(GO:0016605)
0.1 1.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.1 GO:0034399 nuclear periphery(GO:0034399)
0.2 1.0 GO:0044327 dendritic spine head(GO:0044327)
0.2 0.8 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.8 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.7 GO:0097542 ciliary tip(GO:0097542)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
1.6 8.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.3 6.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 5.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 5.1 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
1.1 4.3 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.6 3.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 3.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 2.8 GO:0002020 protease binding(GO:0002020)
0.2 2.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.7 2.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 2.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 2.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 2.0 GO:0046790 virion binding(GO:0046790)
0.1 2.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.9 GO:0030792 methylarsonite methyltransferase activity(GO:0030792)
0.1 1.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)