Motif ID: Zbtb6

Z-value: 1.234


Transcription factors associated with Zbtb6:

Gene SymbolEntrez IDGene Name
Zbtb6 ENSMUSG00000066798.3 Zbtb6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb6mm10_v2_chr2_-_37443096_37443178-0.204.9e-01Click!


Activity profile for motif Zbtb6.

activity profile for motif Zbtb6


Sorted Z-values histogram for motif Zbtb6

Sorted Z-values for motif Zbtb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 189 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102897123 3.971 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr3_+_54156039 3.721 ENSMUST00000029311.6
 Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr6_+_114131229 3.647 ENSMUST00000032451.7
 Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr6_-_60829826 3.369 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr6_+_124997062 2.483 ENSMUST00000159391.1
 Pianp
PILR alpha associated neural protein
chr18_+_33464163 2.240 ENSMUST00000097634.3
 Gm10549
predicted gene 10549
chr2_-_180104463 2.159 ENSMUST00000056480.3
 Hrh3
histamine receptor H3
chr15_+_103503261 2.106 ENSMUST00000023132.3
 Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr11_-_102897146 2.042 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr16_-_8672145 2.037 ENSMUST00000008537.8
 Carhsp1
calcium regulated heat stable protein 1
chr6_+_124996681 1.895 ENSMUST00000032479.4
 Pianp
PILR alpha associated neural protein
chr11_-_89302545 1.574 ENSMUST00000061728.3
 Nog
noggin
chr6_+_29768443 1.542 ENSMUST00000166718.1
ENSMUST00000102995.2
ENSMUST00000115242.2
 Ahcyl2


S-adenosylhomocysteine hydrolase-like 2


chr19_-_31765027 1.487 ENSMUST00000065067.6
 Prkg1
protein kinase, cGMP-dependent, type I
chr4_+_117835387 1.471 ENSMUST00000169885.1
 Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_+_47984793 1.406 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
 Slit2



slit homolog 2 (Drosophila)



chr7_-_4789541 1.385 ENSMUST00000168578.1
 Tmem238
transmembrane protein 238
chr14_-_52316323 1.373 ENSMUST00000135523.1
 Sall2
sal-like 2 (Drosophila)
chr16_-_26371828 1.330 ENSMUST00000023154.2
 Cldn1
claudin 1
chr15_+_39198244 1.283 ENSMUST00000082054.5
ENSMUST00000042917.9
 Rims2

regulating synaptic membrane exocytosis 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 9.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.4 7.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 3.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.9 2.7 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.7 2.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.7 2.1 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.3 2.1 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.4 1.9 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 1.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 1.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.4 1.6 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.5 1.5 GO:2000224 testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224)
0.5 1.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 1.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.3 GO:0097151 spontaneous neurotransmitter secretion(GO:0061669) positive regulation of inhibitory postsynaptic potential(GO:0097151) spontaneous synaptic transmission(GO:0098814)
0.1 1.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.3 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.3 1.2 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.4 1.1 GO:0030070 insulin processing(GO:0030070)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 6.0 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 5.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 4.0 GO:0043235 receptor complex(GO:0043235)
0.8 3.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 3.0 GO:0034704 calcium channel complex(GO:0034704)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)
0.3 2.0 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 2.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 1.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 1.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.7 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.6 GO:0030141 secretory granule(GO:0030141)
0.1 1.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 1.1 GO:1990393 3M complex(GO:1990393)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 3.7 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
1.2 3.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.6 3.4 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 2.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.4 2.7 GO:0043237 laminin-1 binding(GO:0043237)
0.4 2.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 2.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 2.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 2.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 1.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.8 GO:0008201 heparin binding(GO:0008201)
0.1 1.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.4 1.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 1.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 1.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 1.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)