Motif ID: Zbtb7b
Z-value: 1.163
Transcription factors associated with Zbtb7b:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zbtb7b | ENSMUSG00000028042.9 | Zbtb7b |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zbtb7b | mm10_v2_chr3_-_89393294_89393378 | 0.50 | 6.7e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:0002586 | positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499) |
0.8 | 2.4 | GO:1903795 | regulation of inorganic anion transmembrane transport(GO:1903795) |
0.6 | 3.5 | GO:0019695 | choline metabolic process(GO:0019695) |
0.5 | 2.1 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
0.5 | 1.5 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
0.5 | 1.4 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
0.4 | 1.8 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
0.4 | 1.7 | GO:0071930 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) |
0.4 | 2.1 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.4 | 1.2 | GO:0097402 | neuroblast differentiation(GO:0014016) neuroblast migration(GO:0097402) |
0.4 | 3.1 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.3 | 1.4 | GO:0060591 | chondroblast differentiation(GO:0060591) |
0.3 | 2.2 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
0.3 | 0.8 | GO:1902915 | negative regulation of protein import into nucleus, translocation(GO:0033159) protein poly-ADP-ribosylation(GO:0070212) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
0.2 | 0.7 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
0.2 | 4.2 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
0.2 | 1.1 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
0.2 | 0.4 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
0.2 | 1.5 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
0.2 | 0.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.2 | 1.3 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
0.2 | 0.9 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
0.2 | 0.9 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
0.2 | 0.4 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.2 | 1.7 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
0.1 | 1.3 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.1 | 0.4 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474) |
0.1 | 1.0 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.1 | 1.0 | GO:2001185 | regulation of CD8-positive, alpha-beta T cell activation(GO:2001185) |
0.1 | 1.3 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
0.1 | 4.4 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.1 | 0.4 | GO:1902071 | regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
0.1 | 0.7 | GO:0070475 | rRNA base methylation(GO:0070475) |
0.1 | 0.9 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.1 | 0.3 | GO:1903225 | regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225) |
0.1 | 0.3 | GO:0071374 | cellular response to parathyroid hormone stimulus(GO:0071374) |
0.1 | 0.7 | GO:0070458 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
0.1 | 0.8 | GO:0006527 | arginine catabolic process(GO:0006527) |
0.1 | 1.8 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
0.1 | 0.5 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
0.1 | 1.2 | GO:0019243 | glutathione biosynthetic process(GO:0006750) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.1 | 1.1 | GO:0051451 | myoblast migration(GO:0051451) |
0.1 | 0.4 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.1 | 0.4 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.1 | 1.5 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
0.1 | 0.5 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.1 | 0.3 | GO:0010991 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
0.1 | 0.6 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.1 | 0.2 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
0.1 | 0.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.1 | 0.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
0.0 | 0.2 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.0 | 0.3 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
0.0 | 1.0 | GO:0031065 | positive regulation of histone deacetylation(GO:0031065) |
0.0 | 0.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.4 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) negative regulation of protein folding(GO:1903333) |
0.0 | 2.9 | GO:0046785 | microtubule polymerization(GO:0046785) |
0.0 | 0.2 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.0 | 0.6 | GO:0034389 | lipid particle organization(GO:0034389) |
0.0 | 0.2 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.0 | 0.1 | GO:0006788 | heme oxidation(GO:0006788) |
0.0 | 0.1 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
0.0 | 2.8 | GO:0051592 | response to calcium ion(GO:0051592) |
0.0 | 1.5 | GO:0007628 | adult walking behavior(GO:0007628) walking behavior(GO:0090659) |
0.0 | 0.1 | GO:1902219 | regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
0.0 | 0.1 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.0 | 0.1 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
0.0 | 0.2 | GO:0036506 | maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.0 | 0.9 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
0.0 | 1.2 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
0.0 | 0.1 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.0 | 0.3 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.0 | 0.1 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.0 | 0.4 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
0.0 | 3.9 | GO:0008360 | regulation of cell shape(GO:0008360) |
0.0 | 0.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.2 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
0.0 | 0.9 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
0.0 | 0.3 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
0.0 | 0.5 | GO:0009299 | mRNA transcription(GO:0009299) |
0.0 | 0.6 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.0 | 1.9 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 0.3 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 1.1 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
0.0 | 0.4 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.0 | 0.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.0 | 0.5 | GO:0006970 | response to osmotic stress(GO:0006970) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.7 | GO:0035189 | Rb-E2F complex(GO:0035189) |
0.2 | 1.9 | GO:0042587 | glycogen granule(GO:0042587) |
0.2 | 0.9 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.2 | 3.5 | GO:0005605 | basal lamina(GO:0005605) |
0.2 | 1.1 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.1 | 0.5 | GO:0005861 | troponin complex(GO:0005861) |
0.1 | 0.9 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 1.3 | GO:0043203 | axon hillock(GO:0043203) |
0.1 | 0.7 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.1 | 1.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 0.5 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 2.9 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 0.4 | GO:0044326 | dendritic spine neck(GO:0044326) |
0.1 | 0.4 | GO:0070187 | telosome(GO:0070187) |
0.0 | 0.7 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.3 | GO:0044613 | nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543) |
0.0 | 0.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.0 | 0.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.2 | GO:0033010 | paranodal junction(GO:0033010) |
0.0 | 0.4 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
0.0 | 0.2 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.0 | 0.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.2 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 1.5 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 0.1 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
0.0 | 1.1 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.3 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.2 | GO:0048188 | MLL3/4 complex(GO:0044666) Set1C/COMPASS complex(GO:0048188) |
0.0 | 0.4 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 1.1 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.3 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 1.2 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 0.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 0.8 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 1.5 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.6 | GO:0070891 | peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891) |
0.9 | 3.5 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.4 | 4.4 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.3 | 1.3 | GO:0008142 | oxysterol binding(GO:0008142) |
0.3 | 0.8 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
0.3 | 1.5 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
0.2 | 0.7 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.2 | 1.4 | GO:0036122 | BMP binding(GO:0036122) |
0.2 | 2.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
0.2 | 0.5 | GO:0030172 | troponin C binding(GO:0030172) |
0.1 | 0.8 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.1 | 3.1 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.2 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.1 | 0.4 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.1 | 0.4 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.1 | 2.1 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.1 | 0.4 | GO:0000104 | succinate dehydrogenase activity(GO:0000104) |
0.1 | 0.2 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
0.1 | 0.9 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.1 | 1.5 | GO:0035198 | miRNA binding(GO:0035198) |
0.1 | 2.0 | GO:0042805 | actinin binding(GO:0042805) |
0.1 | 1.2 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.1 | 0.2 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.1 | 2.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.1 | 0.3 | GO:0051425 | PTB domain binding(GO:0051425) |
0.1 | 0.6 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 0.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 1.2 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.1 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.3 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.0 | 1.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.4 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.0 | 1.8 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.0 | 0.3 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
0.0 | 0.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.9 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.0 | 0.5 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 0.1 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
0.0 | 0.5 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
0.0 | 0.6 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 1.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.1 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.0 | 0.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 1.1 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.7 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.0 | 1.8 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 1.9 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
0.0 | 0.9 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
0.0 | 0.4 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 0.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
0.0 | 0.1 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.0 | 0.2 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 2.7 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
0.0 | 0.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 0.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.3 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 1.8 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 0.1 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.0 | 3.6 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.2 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
0.0 | 0.3 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.0 | 0.2 | GO:0070402 | NADPH binding(GO:0070402) |