Motif ID: Zbtb7b

Z-value: 1.163


Transcription factors associated with Zbtb7b:

Gene SymbolEntrez IDGene Name
Zbtb7b ENSMUSG00000028042.9 Zbtb7b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7bmm10_v2_chr3_-_89393294_893933780.506.7e-02Click!


Activity profile for motif Zbtb7b.

activity profile for motif Zbtb7b


Sorted Z-values histogram for motif Zbtb7b

Sorted Z-values for motif Zbtb7b



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7b

PNG image of the network

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Top targets:


Showing 1 to 20 of 191 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_141010759 4.182 ENSMUST00000026565.6
 Ifitm3
interferon induced transmembrane protein 3
chr5_+_137288273 3.478 ENSMUST00000024099.4
ENSMUST00000085934.3
 Ache

acetylcholinesterase

chr8_-_105471481 2.877 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr1_+_167598450 2.810 ENSMUST00000111386.1
ENSMUST00000111384.1
 Rxrg

retinoid X receptor gamma

chr4_-_128962420 2.550 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
 Adc


arginine decarboxylase


chr3_+_90541146 2.429 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
 S100a16


S100 calcium binding protein A16


chr7_-_31054815 2.378 ENSMUST00000071697.4
ENSMUST00000108110.3
 Fxyd1

FXYD domain-containing ion transport regulator 1

chr3_+_52268337 2.166 ENSMUST00000053764.5
 Foxo1
forkhead box O1
chr7_+_51879041 2.094 ENSMUST00000107591.2
 Gas2
growth arrest specific 2
chr5_+_137350371 2.064 ENSMUST00000166239.1
ENSMUST00000111054.1
 Ephb4

Eph receptor B4

chr11_-_54068932 2.013 ENSMUST00000093109.4
ENSMUST00000018755.3
 Pdlim4

PDZ and LIM domain 4

chr7_+_51878967 1.998 ENSMUST00000051912.6
 Gas2
growth arrest specific 2
chr17_+_48346401 1.937 ENSMUST00000024791.8
 Trem2
triggering receptor expressed on myeloid cells 2
chr19_-_36736653 1.898 ENSMUST00000087321.2
 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr7_-_142657466 1.882 ENSMUST00000097936.2
ENSMUST00000000033.5
 Igf2

insulin-like growth factor 2

chr2_+_146221921 1.791 ENSMUST00000089257.4
 Insm1
insulinoma-associated 1
chr8_-_84176552 1.772 ENSMUST00000070102.5
 Nanos3
nanos homolog 3 (Drosophila)
chr17_+_48346465 1.632 ENSMUST00000113237.3
 Trem2
triggering receptor expressed on myeloid cells 2
chr1_+_167598384 1.628 ENSMUST00000015987.3
 Rxrg
retinoid X receptor gamma
chrX_+_142227923 1.572 ENSMUST00000042329.5
 Nxt2
nuclear transport factor 2-like export factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 4.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 3.9 GO:0008360 regulation of cell shape(GO:0008360)
1.2 3.6 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.6 3.5 GO:0019695 choline metabolic process(GO:0019695)
0.4 3.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 2.9 GO:0046785 microtubule polymerization(GO:0046785)
0.0 2.8 GO:0051592 response to calcium ion(GO:0051592)
0.8 2.4 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.3 2.2 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.5 2.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 2.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 1.9 GO:0051028 mRNA transport(GO:0051028)
0.4 1.8 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.1 1.8 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.4 1.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 1.7 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.5 1.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 1.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.5 GO:0006883 cellular sodium ion homeostasis(GO:0006883)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.5 GO:0005605 basal lamina(GO:0005605)
0.1 2.9 GO:0034707 chloride channel complex(GO:0034707)
0.2 1.9 GO:0042587 glycogen granule(GO:0042587)
0.3 1.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 1.3 GO:0043203 axon hillock(GO:0043203)
0.1 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.2 GO:0005770 late endosome(GO:0005770)
0.2 1.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 1.1 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.9 3.6 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.0 3.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.9 3.5 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 3.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.7 GO:0008276 protein methyltransferase activity(GO:0008276)
0.2 2.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 2.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 2.0 GO:0042805 actinin binding(GO:0042805)
0.0 1.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.8 GO:0030332 cyclin binding(GO:0030332)
0.0 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.8 GO:0001047 core promoter binding(GO:0001047)
0.3 1.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.5 GO:0035198 miRNA binding(GO:0035198)
0.2 1.4 GO:0036122 BMP binding(GO:0036122)
0.3 1.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)