Motif ID: Zfhx3

Z-value: 0.983


Transcription factors associated with Zfhx3:

Gene SymbolEntrez IDGene Name
Zfhx3 ENSMUSG00000038872.8 Zfhx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfhx3mm10_v2_chr8_+_108714644_1087146440.185.4e-01Click!


Activity profile for motif Zfhx3.

activity profile for motif Zfhx3


Sorted Z-values histogram for motif Zfhx3

Sorted Z-values for motif Zfhx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfhx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 83 entries
PromoterScoreRefseqGene SymbolGene Name
chrM_+_7759 1.663 ENSMUST00000082407.1
ENSMUST00000082408.1
 mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chrM_-_14060 1.428 ENSMUST00000082419.1
 mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chrM_+_2743 1.358 ENSMUST00000082392.1
 mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr1_-_24612700 1.350 ENSMUST00000088336.1
 Gm10222
predicted gene 10222
chr2_+_82053222 1.215 ENSMUST00000047527.7
 Zfp804a
zinc finger protein 804A
chrM_+_9870 1.172 ENSMUST00000084013.1
 mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr15_-_79285502 1.046 ENSMUST00000165408.1
 Baiap2l2
BAI1-associated protein 2-like 2
chr13_-_110280103 0.983 ENSMUST00000167824.1
 Rab3c
RAB3C, member RAS oncogene family
chr5_-_107875035 0.956 ENSMUST00000138111.1
ENSMUST00000112642.1
 Evi5

ecotropic viral integration site 5

chrM_+_7005 0.947 ENSMUST00000082405.1
 mt-Co2
mitochondrially encoded cytochrome c oxidase II
chrM_+_14138 0.908 ENSMUST00000082421.1
 mt-Cytb
mitochondrially encoded cytochrome b
chr8_-_67818284 0.852 ENSMUST00000120071.1
 Psd3
pleckstrin and Sec7 domain containing 3
chr4_+_82065924 0.846 ENSMUST00000161588.1
 Gm5860
predicted gene 5860
chrM_+_9452 0.797 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr10_-_56228636 0.720 ENSMUST00000099739.3
 Tbc1d32
TBC1 domain family, member 32
chr12_+_71170589 0.714 ENSMUST00000129376.1
 2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr1_+_179961110 0.702 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr2_-_63184253 0.656 ENSMUST00000075052.3
ENSMUST00000112454.1
 Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr5_+_107497718 0.648 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr9_+_95857597 0.614 ENSMUST00000034980.7
 Atr
ataxia telangiectasia and Rad3 related

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 1.2 GO:0007097 nuclear migration(GO:0007097)
0.0 1.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 1.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.9 GO:0033762 response to glucagon(GO:0033762)
0.0 0.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.8 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.1 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.6 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2 0.6 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.6 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.6 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 0.5 GO:2000224 testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.5 GO:0022900 electron transport chain(GO:0022900)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.4 GO:0032929 negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.7 GO:0070469 respiratory chain(GO:0070469)
0.1 1.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.0 GO:0071439 clathrin complex(GO:0071439)
0.1 0.9 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 0.6 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0032432 actin filament bundle(GO:0032432)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1 0.6 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)