Motif ID: Zfp105

Z-value: 0.754


Transcription factors associated with Zfp105:

Gene SymbolEntrez IDGene Name
Zfp105 ENSMUSG00000057895.5 Zfp105

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_1229230990.332.5e-01Click!


Activity profile for motif Zfp105.

activity profile for motif Zfp105


Sorted Z-values histogram for motif Zfp105

Sorted Z-values for motif Zfp105



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp105

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_17574268 3.521 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_+_144892813 2.895 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr1_-_190170671 2.064 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr8_+_128359065 1.545 ENSMUST00000026917.8
 Nrp1
neuropilin 1
chr12_-_90738438 1.508 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr11_-_100411874 1.429 ENSMUST00000141840.1
 Leprel4
leprecan-like 4
chrM_+_3906 1.260 ENSMUST00000082396.1
 mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr6_-_53820764 1.259 ENSMUST00000127748.2
 Tril
TLR4 interactor with leucine-rich repeats
chr5_+_13399309 1.180 ENSMUST00000030714.7
ENSMUST00000141968.1
 Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr5_-_111761697 1.169 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr4_+_105157339 1.095 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr18_+_69344503 0.934 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr11_+_44617310 0.819 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr6_+_29859374 0.808 ENSMUST00000115238.3
 Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr2_-_91931774 0.798 ENSMUST00000069423.6
 Mdk
midkine
chr15_+_99006056 0.797 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr2_-_177267036 0.709 ENSMUST00000108963.1
 Gm14409
predicted gene 14409
chr13_-_67609667 0.628 ENSMUST00000012873.8
 AA987161
expressed sequence AA987161
chr18_+_37484955 0.516 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr9_+_58134535 0.516 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
 Stra6



stimulated by retinoic acid gene 6



chr13_-_67609617 0.488 ENSMUST00000138725.1
 AA987161
expressed sequence AA987161
chr1_-_13589717 0.433 ENSMUST00000027068.4
 Tram1
translocating chain-associating membrane protein 1
chr8_-_84773381 0.402 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr9_-_19928282 0.399 ENSMUST00000082002.5
 Gm7808
predicted pseudogene 7808
chr1_-_184732616 0.342 ENSMUST00000048572.6
 Hlx
H2.0-like homeobox
chr4_-_3973581 0.316 ENSMUST00000089430.4
 Gm11808
predicted gene 11808
chr18_+_35829798 0.315 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr14_+_11227511 0.282 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr1_+_156366037 0.243 ENSMUST00000102782.3
 Gm2000
predicted gene 2000
chr2_+_107290590 0.239 ENSMUST00000037012.2
 Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr18_+_30272747 0.227 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
 Pik3c3


phosphoinositide-3-kinase, class 3


chr11_-_101466222 0.225 ENSMUST00000040430.7
 Vat1
vesicle amine transport protein 1 homolog (T californica)
chr5_+_136953246 0.219 ENSMUST00000111094.1
ENSMUST00000111097.1
 Fis1

fission 1 (mitochondrial outer membrane) homolog (yeast)

chr5_+_19907502 0.205 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_-_21501418 0.187 ENSMUST00000044043.2
 Gm11273
predicted gene 11273
chr15_-_81843699 0.184 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chr11_-_102316691 0.171 ENSMUST00000107115.1
ENSMUST00000128016.1
 Ubtf

upstream binding transcription factor, RNA polymerase I

chr15_+_102460076 0.163 ENSMUST00000164688.1
 Prr13
proline rich 13
chr1_+_179960472 0.157 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr6_-_127151044 0.131 ENSMUST00000000188.8
 Ccnd2
cyclin D2
chr8_-_11008458 0.128 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr10_-_128549102 0.116 ENSMUST00000176906.1
 Rpl41
ribosomal protein L41
chr7_+_66109474 0.099 ENSMUST00000036372.6
 Chsy1
chondroitin sulfate synthase 1
chr18_+_35770318 0.069 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr9_+_78175898 0.035 ENSMUST00000180974.1
 C920006O11Rik
RIKEN cDNA C920006O11 gene
chr7_-_34313531 0.021 ENSMUST00000108074.1
 4931406P16Rik
RIKEN cDNA 4931406P16 gene
chr15_+_85510812 0.013 ENSMUST00000079690.2
 Gm4825
predicted pseudogene 4825
chr14_-_36968679 0.011 ENSMUST00000067700.6
 Ccser2
coiled-coil serine rich 2
chr10_-_96409038 0.004 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.7 2.1 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.3 1.5 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.3 0.8 GO:0030421 defecation(GO:0030421)
0.3 2.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.5 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 0.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.9 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.3 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 1.3 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.4 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.2 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0097443 sorting endosome(GO:0097443)
0.2 1.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.7 GO:0038191 neuropilin binding(GO:0038191)
0.4 2.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 2.1 GO:0050693 LBD domain binding(GO:0050693)
0.2 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)