Motif ID: Zfp219_Zfp740

Z-value: 0.935

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp219mm10_v2_chr14_-_52020698_52020737-0.411.5e-01Click!
Zfp740mm10_v2_chr15_+_102203639_102203709-0.078.2e-01Click!


Activity profile for motif Zfp219_Zfp740.

activity profile for motif Zfp219_Zfp740


Sorted Z-values histogram for motif Zfp219_Zfp740

Sorted Z-values for motif Zfp219_Zfp740



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_897782 1.559 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr2_+_48949495 1.393 ENSMUST00000112745.1
 Mbd5
methyl-CpG binding domain protein 5
chr12_-_27342696 1.277 ENSMUST00000079063.5
 Sox11
SRY-box containing gene 11
chr1_-_64121389 1.230 ENSMUST00000055001.3
 Klf7
Kruppel-like factor 7 (ubiquitous)
chr10_-_127620922 1.139 ENSMUST00000118455.1
 Lrp1
low density lipoprotein receptor-related protein 1
chrX_-_94123087 1.107 ENSMUST00000113925.1
 Zfx
zinc finger protein X-linked
chr6_+_110645572 1.061 ENSMUST00000071076.6
ENSMUST00000172951.1
 Grm7

glutamate receptor, metabotropic 7

chr16_+_44173271 1.011 ENSMUST00000088356.4
ENSMUST00000169582.1
 Gm608

predicted gene 608

chr12_-_118301429 1.002 ENSMUST00000026367.9
 Sp4
trans-acting transcription factor 4
chr13_-_29984219 0.982 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr11_-_89302545 0.953 ENSMUST00000061728.3
 Nog
noggin
chr6_-_136173492 0.898 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_+_164960809 0.884 ENSMUST00000124372.1
 Slc12a5
solute carrier family 12, member 5
chr3_+_136670679 0.850 ENSMUST00000056758.8
 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chrX_-_38564519 0.847 ENSMUST00000016681.8
 Cul4b
cullin 4B
chr4_-_151861667 0.833 ENSMUST00000169423.2
 Camta1
calmodulin binding transcription activator 1
chr10_-_127620960 0.826 ENSMUST00000121829.1
 Lrp1
low density lipoprotein receptor-related protein 1
chr1_-_124045247 0.819 ENSMUST00000112603.2
 Dpp10
dipeptidylpeptidase 10
chr3_+_28263563 0.805 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
 Tnik






TRAF2 and NCK interacting kinase






chr7_-_78578308 0.786 ENSMUST00000039431.7
 Ntrk3
neurotrophic tyrosine kinase, receptor, type 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 169 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.1 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 2.0 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 1.7 GO:1990403 embryonic brain development(GO:1990403)
0.1 1.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.3 1.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 1.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.4 1.3 GO:0060023 soft palate development(GO:0060023)
0.4 1.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.4 1.1 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 1.1 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 1.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2 1.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 1.0 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)
0.3 0.9 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.9 GO:0042118 endothelial cell activation(GO:0042118)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.7 GO:0010369 chromocenter(GO:0010369)
0.0 1.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.5 GO:0032590 dendrite membrane(GO:0032590)
0.2 1.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 1.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.1 0.8 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.2 1.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 1.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 1.1 GO:0070905 serine binding(GO:0070905)
0.2 1.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 1.0 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.2 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.2 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)