Motif ID: Zic3

Z-value: 0.819


Transcription factors associated with Zic3:

Gene SymbolEntrez IDGene Name
Zic3 ENSMUSG00000067860.5 Zic3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic3mm10_v2_chrX_+_58030999_580310180.441.1e-01Click!


Activity profile for motif Zic3.

activity profile for motif Zic3


Sorted Z-values histogram for motif Zic3

Sorted Z-values for motif Zic3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_32646586 1.153 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr10_+_106470281 1.077 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chrY_-_1286563 1.008 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr2_-_39190687 0.884 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr11_+_116280939 0.878 ENSMUST00000055872.2
Galr2
galanin receptor 2
chr4_-_53159885 0.864 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr4_+_108165449 0.832 ENSMUST00000116309.3
ENSMUST00000116307.1
Echdc2

enoyl Coenzyme A hydratase domain containing 2

chr7_+_127800604 0.786 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr7_-_141010759 0.752 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr17_+_86963279 0.737 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chrY_-_1245685 0.730 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr4_+_108165432 0.701 ENSMUST00000052999.6
Echdc2
enoyl Coenzyme A hydratase domain containing 2
chr8_+_4248188 0.686 ENSMUST00000110993.1
Gm14378
predicted gene 14378
chrX_+_56454871 0.679 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr14_-_55560340 0.678 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr2_+_71529085 0.676 ENSMUST00000152711.1
Dlx1
distal-less homeobox 1
chr16_-_91044473 0.646 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr11_-_72266596 0.630 ENSMUST00000021161.6
ENSMUST00000140167.1
Slc13a5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr19_+_42045792 0.618 ENSMUST00000172244.1
ENSMUST00000081714.4
Hoga1

4-hydroxy-2-oxoglutarate aldolase 1

chr5_+_137288273 0.617 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 104 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.4 1.2 GO:0003032 detection of oxygen(GO:0003032)
0.3 1.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 1.1 GO:0008209 androgen metabolic process(GO:0008209)
0.2 1.0 GO:0003383 apical constriction(GO:0003383)
0.2 0.9 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 0.9 GO:0036233 glycine import(GO:0036233)
0.1 0.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.8 GO:0051693 actin filament capping(GO:0051693)
0.2 0.7 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.1 0.7 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 0.6 GO:0006842 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746)
0.2 0.6 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.6 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.6 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 1.2 GO:0072562 blood microparticle(GO:0072562)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.0 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.2 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.2 1.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 1.2 GO:0005534 galactose binding(GO:0005534)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 0.9 GO:0004966 galanin receptor activity(GO:0004966)
0.3 0.9 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.2 0.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 0.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.6 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.4 GO:0004962 endothelin receptor activity(GO:0004962)