Motif ID: Zkscan1

Z-value: 0.818


Transcription factors associated with Zkscan1:

Gene SymbolEntrez IDGene Name
Zkscan1 ENSMUSG00000029729.6 Zkscan1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_138085147-0.651.2e-02Click!


Activity profile for motif Zkscan1.

activity profile for motif Zkscan1


Sorted Z-values histogram for motif Zkscan1

Sorted Z-values for motif Zkscan1



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan1

PNG image of the network

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Top targets:


Showing 1 to 20 of 120 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_75048837 3.997 ENSMUST00000179762.1
ENSMUST00000065408.9
 Ly6c1

lymphocyte antigen 6 complex, locus C1

chr15_-_74997634 1.872 ENSMUST00000023248.6
 Ly6a
lymphocyte antigen 6 complex, locus A
chr5_-_28210022 1.794 ENSMUST00000118882.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr15_-_79164477 1.561 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr4_+_101419277 1.548 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
 Ak4


adenylate kinase 4


chr10_+_86300372 1.500 ENSMUST00000020234.7
 Timp3
tissue inhibitor of metalloproteinase 3
chr7_+_112225856 1.395 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
 Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr4_+_138972885 1.309 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
 Tmco4


transmembrane and coiled-coil domains 4


chr4_-_42168603 1.303 ENSMUST00000098121.3
 Gm13305
predicted gene 13305
chr2_+_84734050 1.053 ENSMUST00000090729.2
 Ypel4
yippee-like 4 (Drosophila)
chr3_+_62338344 1.012 ENSMUST00000079300.6
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr14_-_8309770 0.991 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr5_+_64812336 0.983 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chrX_+_20870166 0.916 ENSMUST00000115342.3
ENSMUST00000009530.4
 Timp1

tissue inhibitor of metalloproteinase 1

chr15_+_101224207 0.904 ENSMUST00000000543.4
 Grasp
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr15_-_75111684 0.887 ENSMUST00000100542.3
 Ly6c2
lymphocyte antigen 6 complex, locus C2
chr1_+_171840607 0.863 ENSMUST00000136479.1
ENSMUST00000042302.6
 Cd84

CD84 antigen

chr9_-_103480328 0.850 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr5_-_70842617 0.834 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr18_+_61105844 0.812 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.6 GO:0048484 enteric nervous system development(GO:0048484)
0.1 1.5 GO:0046033 AMP metabolic process(GO:0046033)
0.0 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.3 1.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 0.9 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.2 0.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.7 GO:1903975 regulation of glial cell migration(GO:1903975)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 0.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.5 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.2 1.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)
0.3 0.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 0.3 GO:0030120 vesicle coat(GO:0030120) clathrin vesicle coat(GO:0030125)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.6 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.5 1.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.4 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0 1.1 GO:0019955 cytokine binding(GO:0019955)
0.1 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.8 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.2 0.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0019841 retinol binding(GO:0019841)
0.2 0.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.5 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0016751 S-succinyltransferase activity(GO:0016751)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)