Motif ID: Zkscan3

Z-value: 0.592


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_214027550.117.1e-01Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_75422524 0.763 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr5_+_24985840 0.631 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr12_+_112588753 0.539 ENSMUST00000101029.2
 Inf2
inverted formin, FH2 and WH2 domain containing
chr11_-_75422586 0.484 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr4_+_156026120 0.376 ENSMUST00000103173.3
 Tnfrsf18
tumor necrosis factor receptor superfamily, member 18
chr3_-_95687846 0.359 ENSMUST00000015994.3
ENSMUST00000148854.1
ENSMUST00000117782.1
 Adamtsl4


ADAMTS-like 4


chr5_-_88675190 0.355 ENSMUST00000133532.1
ENSMUST00000150438.1
 Grsf1

G-rich RNA sequence binding factor 1

chr14_+_51893610 0.328 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr12_+_76533540 0.317 ENSMUST00000075249.4
 Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr10_-_33951190 0.305 ENSMUST00000048222.4
 Zufsp
zinc finger with UFM1-specific peptidase domain
chr4_+_156026304 0.298 ENSMUST00000040274.7
ENSMUST00000122001.1
 Tnfrsf18

tumor necrosis factor receptor superfamily, member 18

chr6_+_125552948 0.298 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chrX_-_75874536 0.286 ENSMUST00000033547.7
 Pls3
plastin 3 (T-isoform)
chr13_-_19395728 0.260 ENSMUST00000039694.7
 Stard3nl
STARD3 N-terminal like
chr18_+_61105844 0.255 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor
chr6_-_43666158 0.253 ENSMUST00000114644.2
ENSMUST00000150599.1
ENSMUST00000067888.7
 Tpk1


thiamine pyrophosphokinase


chr13_+_104109737 0.243 ENSMUST00000044385.7
 Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr13_+_104109752 0.242 ENSMUST00000160322.1
ENSMUST00000159574.1
 Sgtb

small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta

chr3_+_146499850 0.227 ENSMUST00000118280.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr3_+_146500071 0.214 ENSMUST00000119130.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr5_-_88675613 0.204 ENSMUST00000113234.1
ENSMUST00000153565.1
 Grsf1

G-rich RNA sequence binding factor 1

chr11_-_102218923 0.198 ENSMUST00000131254.1
 Hdac5
histone deacetylase 5
chr2_+_32646586 0.196 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chrX_-_17571563 0.193 ENSMUST00000177213.1
 Fundc1
FUN14 domain containing 1
chr3_-_63929376 0.189 ENSMUST00000061706.6
 E130311K13Rik
RIKEN cDNA E130311K13 gene
chr1_-_40790642 0.167 ENSMUST00000039672.5
 Mfsd9
major facilitator superfamily domain containing 9
chr5_+_24586721 0.164 ENSMUST00000121863.1
ENSMUST00000088295.4
 Chpf2

chondroitin polymerizing factor 2

chr13_-_32851176 0.152 ENSMUST00000091668.5
ENSMUST00000076352.6
 Serpinb1a

serine (or cysteine) peptidase inhibitor, clade B, member 1a

chr1_+_180942452 0.140 ENSMUST00000027800.8
 Tmem63a
transmembrane protein 63a
chr14_+_57424054 0.136 ENSMUST00000122063.1
 Ift88
intraflagellar transport 88
chr13_+_42709482 0.136 ENSMUST00000066928.5
ENSMUST00000148891.1
 Phactr1

phosphatase and actin regulator 1

chrX_-_17572241 0.134 ENSMUST00000176638.1
ENSMUST00000026016.6
 Fundc1

FUN14 domain containing 1

chr2_+_156613664 0.134 ENSMUST00000169464.2
ENSMUST00000109567.3
 Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr1_-_173333503 0.133 ENSMUST00000038227.4
 Darc
Duffy blood group, chemokine receptor
chr15_-_3979432 0.123 ENSMUST00000022791.8
 Fbxo4
F-box protein 4
chr7_+_101896340 0.123 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
 Anapc15


anaphase prompoting complex C subunit 15


chr8_-_70760889 0.116 ENSMUST00000038626.8
 Mpv17l2
MPV17 mitochondrial membrane protein-like 2
chr8_+_33732237 0.116 ENSMUST00000171010.1
 Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr7_-_81345189 0.114 ENSMUST00000080813.4
 Rps17
ribosomal protein S17
chr2_+_104095796 0.107 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr13_+_44730726 0.106 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
 Jarid2


jumonji, AT rich interactive domain 2


chr8_-_116978908 0.106 ENSMUST00000070577.5
 1700030J22Rik
RIKEN cDNA 1700030J22 gene
chr4_+_63544747 0.098 ENSMUST00000035301.6
 Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr8_-_105758570 0.093 ENSMUST00000155038.2
ENSMUST00000013294.9
 Gfod2

glucose-fructose oxidoreductase domain containing 2

chr12_-_69724830 0.086 ENSMUST00000021370.8
 L2hgdh
L-2-hydroxyglutarate dehydrogenase
chr2_+_31670714 0.084 ENSMUST00000038474.7
ENSMUST00000137156.1
 Exosc2

exosome component 2

chr8_-_106893581 0.072 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
 Chtf8



CTF8, chromosome transmission fidelity factor 8



chr13_-_38658991 0.068 ENSMUST00000001757.7
 Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr8_+_71396853 0.067 ENSMUST00000002473.8
 Babam1
BRISC and BRCA1 A complex member 1
chr17_-_35673738 0.064 ENSMUST00000001565.8
 Gtf2h4
general transcription factor II H, polypeptide 4
chr7_+_126759601 0.064 ENSMUST00000050201.4
ENSMUST00000057669.9
 Mapk3

mitogen-activated protein kinase 3

chr13_-_100786402 0.055 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
 Ccnb1


cyclin B1


chr7_-_127020321 0.054 ENSMUST00000032918.2
 Pagr1a
PAXIP1 associated glutamate rich protein 1A
chr1_-_39651165 0.052 ENSMUST00000053355.4
 Creg2
cellular repressor of E1A-stimulated genes 2
chr2_+_121295437 0.050 ENSMUST00000110639.1
 Map1a
microtubule-associated protein 1 A
chr9_+_114688782 0.039 ENSMUST00000047404.6
 Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chr8_+_124897877 0.034 ENSMUST00000034467.5
 Sprtn
SprT-like N-terminal domain
chr5_+_122643878 0.033 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
 P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr2_-_30194112 0.033 ENSMUST00000113659.1
ENSMUST00000113660.1
 Ccbl1

cysteine conjugate-beta lyase 1

chr8_+_70616816 0.031 ENSMUST00000052437.3
 Lrrc25
leucine rich repeat containing 25
chr3_+_79629074 0.027 ENSMUST00000029388.8
 4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr5_-_73338580 0.024 ENSMUST00000087195.5
 Ociad2
OCIA domain containing 2
chr6_+_127453705 0.022 ENSMUST00000039680.5
 Parp11
poly (ADP-ribose) polymerase family, member 11
chr2_+_121171155 0.015 ENSMUST00000110658.1
 Tubgcp4
tubulin, gamma complex associated protein 4
chr1_+_132298606 0.015 ENSMUST00000046071.4
 Klhdc8a
kelch domain containing 8A
chr1_+_58795371 0.007 ENSMUST00000027189.8
 Casp8
caspase 8
chr2_+_155775333 0.006 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr11_-_102365111 0.005 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr8_-_124897685 0.003 ENSMUST00000098312.2
 Exoc8
exocyst complex component 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.7 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.1 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.3 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.0 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703)
0.0 0.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.1 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0005113 patched binding(GO:0005113)