Motif ID: Ar

Z-value: 1.136


Transcription factors associated with Ar:

Gene SymbolEntrez IDGene Name
Ar ENSMUSG00000046532.7 Ar



Activity profile for motif Ar.

activity profile for motif Ar


Sorted Z-values histogram for motif Ar

Sorted Z-values for motif Ar



Network of associatons between targets according to the STRING database.



First level regulatory network of Ar

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_98053415 5.325 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr5_+_17574726 5.215 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_-_173942445 4.831 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr6_+_5725639 4.817 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr12_-_25096080 4.736 ENSMUST00000020974.6
 Id2
inhibitor of DNA binding 2
chr6_+_5725812 4.402 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr11_+_16752203 4.114 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chr3_-_113577743 4.023 ENSMUST00000067980.5
 Amy1
amylase 1, salivary
chr3_-_113574242 3.847 ENSMUST00000142505.2
 Amy1
amylase 1, salivary
chr3_-_113574758 3.830 ENSMUST00000106540.1
 Amy1
amylase 1, salivary
chr17_+_56764738 3.746 ENSMUST00000007747.8
 Dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr3_-_84259812 3.641 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr7_-_46179929 3.463 ENSMUST00000033123.6
 Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr3_+_117575268 3.141 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr7_-_16476765 2.721 ENSMUST00000002053.8
 Npas1
neuronal PAS domain protein 1
chr10_-_32410335 2.663 ENSMUST00000092603.4
 Nkain2
Na+/K+ transporting ATPase interacting 2
chr8_+_72646679 2.652 ENSMUST00000161386.1
ENSMUST00000093427.4
 Nwd1

NACHT and WD repeat domain containing 1

chr5_+_110879788 2.604 ENSMUST00000156290.2
ENSMUST00000040111.9
 Ttc28

tetratricopeptide repeat domain 28

chr15_-_102524615 2.585 ENSMUST00000023814.7
 Npff
neuropeptide FF-amide peptide precursor
chr7_-_97417730 2.584 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 119 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 9.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.7 8.5 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 6.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
1.5 6.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.9 5.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 4.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 4.8 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.9 4.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.8 4.1 GO:0070459 prolactin secretion(GO:0070459)
1.2 3.5 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.6 3.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 2.7 GO:0042711 maternal behavior(GO:0042711)
0.4 2.6 GO:0070253 somatostatin secretion(GO:0070253)
0.1 2.6 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.8 2.4 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 2.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 2.2 GO:0006397 mRNA processing(GO:0006397)
0.7 2.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.5 2.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 2.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.3 GO:0005615 extracellular space(GO:0005615)
0.4 9.3 GO:0033270 paranode region of axon(GO:0033270)
3.1 9.2 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.2 5.0 GO:0005682 U5 snRNP(GO:0005682)
1.0 4.1 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.9 3.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 3.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.7 GO:0031594 neuromuscular junction(GO:0031594)
0.2 2.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 2.4 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.1 1.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.6 GO:0005922 connexon complex(GO:0005922)
0.1 1.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.4 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.9 11.7 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.5 9.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 7.4 GO:0030507 spectrin binding(GO:0030507)
0.1 5.9 GO:0017022 myosin binding(GO:0017022)
0.4 5.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 4.5 GO:0001047 core promoter binding(GO:0001047)
0.1 4.4 GO:0005267 potassium channel activity(GO:0005267)
1.4 4.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 4.0 GO:0044325 ion channel binding(GO:0044325)
0.2 3.0 GO:0043495 protein anchor(GO:0043495)
0.9 2.6 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.8 2.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 2.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 2.1 GO:0005537 mannose binding(GO:0005537)
0.2 2.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.3 1.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 7.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 4.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 2.1 PID_FOXO_PATHWAY FoxO family signaling
0.0 2.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.9 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.5 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.2 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 ST_ADRENERGIC Adrenergic Pathway
0.0 0.9 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.8 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 0.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.7 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.2 7.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.9 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 3.7 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.4 2.6 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.2 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.3 2.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 1.9 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.8 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.2 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.0 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.0 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.0 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits