Motif ID: Bbx

Z-value: 0.317


Transcription factors associated with Bbx:

Gene SymbolEntrez IDGene Name
Bbx ENSMUSG00000022641.9 Bbx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bbxmm10_v2_chr16_-_50432340_50432409-0.143.7e-01Click!


Activity profile for motif Bbx.

activity profile for motif Bbx


Sorted Z-values histogram for motif Bbx

Sorted Z-values for motif Bbx



Network of associatons between targets according to the STRING database.



First level regulatory network of Bbx

PNG image of the network

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Top targets:


Showing 1 to 20 of 30 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_21111452 1.940 ENSMUST00000075132.6
 Cdh12
cadherin 12
chr5_-_146585239 1.176 ENSMUST00000036211.6
 Gpr12
G-protein coupled receptor 12
chr18_+_37421418 1.041 ENSMUST00000053073.4
 Pcdhb11
protocadherin beta 11
chrX_+_159708593 0.844 ENSMUST00000080394.6
 Sh3kbp1
SH3-domain kinase binding protein 1
chr10_+_86021961 0.664 ENSMUST00000130320.1
 Fbxo7
F-box protein 7
chr13_+_49608030 0.631 ENSMUST00000021822.5
 Ogn
osteoglycin
chr2_+_136892168 0.610 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chrX_+_140367494 0.547 ENSMUST00000141660.1
 Frmpd3
FERM and PDZ domain containing 3
chr1_+_180111339 0.542 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr13_-_52530827 0.519 ENSMUST00000057442.6
 Diras2
DIRAS family, GTP-binding RAS-like 2
chr8_-_41054771 0.499 ENSMUST00000093534.4
 Mtus1
mitochondrial tumor suppressor 1
chr11_+_105146893 0.476 ENSMUST00000100338.1
 Gm10842
predicted gene 10842
chr16_+_20693263 0.384 ENSMUST00000149543.1
ENSMUST00000118919.1
 Fam131a

family with sequence similarity 131, member A

chrX_-_107816238 0.371 ENSMUST00000120722.1
 2610002M06Rik
RIKEN cDNA 2610002M06 gene
chrX_-_150814265 0.353 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
 Maged2


melanoma antigen, family D, 2


chr10_+_84622365 0.326 ENSMUST00000077175.5
 Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
chr12_+_103388656 0.264 ENSMUST00000101094.2
ENSMUST00000021620.6
 Otub2

OTU domain, ubiquitin aldehyde binding 2

chr8_+_45658273 0.249 ENSMUST00000153798.1
 Sorbs2
sorbin and SH3 domain containing 2
chr1_-_163725123 0.216 ENSMUST00000159679.1
 Mettl11b
methyltransferase like 11B
chr8_+_45658731 0.166 ENSMUST00000143820.1
ENSMUST00000132139.1
 Sorbs2

sorbin and SH3 domain containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.6 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 0.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.5 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)

Gene overrepresentation in cellular_component category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.6 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes