Motif ID: Bcl6b

Z-value: 0.549


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.408.9e-03Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 71 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 5.154 ENSMUST00000107377.3
 Tnc
tenascin C
chr19_-_5797410 2.750 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr1_-_173942445 2.666 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr16_-_74411776 2.520 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr10_+_57794335 2.200 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr16_-_74411292 2.093 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chrX_+_151344171 2.090 ENSMUST00000073364.5
 Fam120c
family with sequence similarity 120, member C
chr9_-_90255927 1.741 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr13_-_98815408 1.613 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
 Fcho2



FCH domain only 2



chr10_+_81633694 1.468 ENSMUST00000140345.1
ENSMUST00000126323.1
 Ankrd24

ankyrin repeat domain 24

chr2_-_65567505 1.365 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr8_+_13907748 1.362 ENSMUST00000043520.3
 Fbxo25
F-box protein 25
chr2_-_65567465 1.343 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr12_-_40134175 1.314 ENSMUST00000078481.7
ENSMUST00000002640.5
 Scin

scinderin

chr16_-_34263179 1.307 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr16_-_34262830 1.217 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr2_+_119594288 1.182 ENSMUST00000147425.1
ENSMUST00000153581.1
 1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr12_-_98577940 1.134 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr2_-_180824596 1.015 ENSMUST00000148700.1
 Gm14340
predicted gene 14340
chr6_+_149309444 0.991 ENSMUST00000100765.4
 2810474O19Rik
RIKEN cDNA 2810474O19 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 5.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.5 4.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 3.4 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.6 2.8 GO:0035063 nuclear speck organization(GO:0035063)
0.5 2.7 GO:0046684 response to pyrethroid(GO:0046684)
0.1 2.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.3 2.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.9 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 0.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.6 GO:0015862 uridine transport(GO:0015862)
0.1 0.5 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.1 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.3 GO:0071918 urea transmembrane transport(GO:0071918)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 4.6 GO:0030673 axolemma(GO:0030673)
0.2 3.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 1.6 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0005903 brush border(GO:0005903)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0030478 actin cap(GO:0030478)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 5.2 GO:0045545 syndecan binding(GO:0045545)
0.6 4.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.7 GO:0031402 sodium ion binding(GO:0031402)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 2.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 1.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.2 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.1 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 1.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.1 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1