Motif ID: Bptf

Z-value: 1.601


Transcription factors associated with Bptf:

Gene SymbolEntrez IDGene Name
Bptf ENSMUSG00000040481.10 Bptf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bptfmm10_v2_chr11_-_107131922_1071319540.671.8e-06Click!


Activity profile for motif Bptf.

activity profile for motif Bptf


Sorted Z-values histogram for motif Bptf

Sorted Z-values for motif Bptf



Network of associatons between targets according to the STRING database.



First level regulatory network of Bptf

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_116968969 11.860 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr4_+_144892813 10.133 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr16_+_43510267 9.914 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr17_+_35076902 7.470 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr8_-_84773381 6.031 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr4_+_144893077 6.006 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr15_+_77084367 6.001 ENSMUST00000181870.1
 1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr17_+_35077080 5.943 ENSMUST00000172959.1
 Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr16_+_43508118 5.759 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr7_+_131410601 5.621 ENSMUST00000015829.7
ENSMUST00000117518.1
 Acadsb

acyl-Coenzyme A dehydrogenase, short/branched chain

chr4_+_144893127 5.414 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr10_+_112271123 5.344 ENSMUST00000092175.2
 Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr16_+_43247278 5.166 ENSMUST00000114691.1
ENSMUST00000079441.6
 Zbtb20

zinc finger and BTB domain containing 20

chr1_+_20917856 5.141 ENSMUST00000167119.1
 Paqr8
progestin and adipoQ receptor family member VIII
chr5_+_17574268 4.702 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_+_5218516 4.668 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr4_-_53159885 4.550 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr3_+_5218546 4.392 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr16_+_37916440 4.189 ENSMUST00000061274.7
 Gpr156
G protein-coupled receptor 156
chr17_+_75178797 4.154 ENSMUST00000112516.1
ENSMUST00000135447.1
 Ltbp1

latent transforming growth factor beta binding protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 352 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 23.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
2.0 21.6 GO:0042572 retinol metabolic process(GO:0042572)
0.5 15.2 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.1 14.3 GO:0008360 regulation of cell shape(GO:0008360)
0.1 7.0 GO:0008643 carbohydrate transport(GO:0008643)
0.6 6.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.3 6.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.4 6.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 5.7 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.5 5.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.0 5.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
1.0 5.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.0 4.9 GO:0046684 response to pyrethroid(GO:0046684)
0.8 4.7 GO:0003350 pulmonary myocardium development(GO:0003350)
1.1 4.6 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.0 4.6 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 4.3 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 4.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
1.3 4.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.5 4.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.7 GO:0043197 dendritic spine(GO:0043197)
0.0 9.5 GO:0000139 Golgi membrane(GO:0000139)
0.2 9.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 8.9 GO:0030139 endocytic vesicle(GO:0030139)
0.1 7.1 GO:0045171 intercellular bridge(GO:0045171)
2.2 6.6 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.4 6.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 5.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 4.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 4.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 4.2 GO:0005614 interstitial matrix(GO:0005614)
1.3 4.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 4.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 3.7 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 3.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 3.3 GO:0031519 PcG protein complex(GO:0031519)
0.1 3.3 GO:0030667 secretory granule membrane(GO:0030667)
0.4 3.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 3.0 GO:0071564 npBAF complex(GO:0071564)
0.1 2.9 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 233 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 21.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 17.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
4.5 13.4 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.4 8.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 7.6 GO:0008270 zinc ion binding(GO:0008270)
1.7 6.6 GO:0050436 microfibril binding(GO:0050436)
0.1 6.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 6.2 GO:0031402 sodium ion binding(GO:0031402)
0.1 6.2 GO:0030507 spectrin binding(GO:0030507)
0.1 5.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 5.4 GO:0005158 insulin receptor binding(GO:0005158)
0.2 5.2 GO:0003785 actin monomer binding(GO:0003785)
0.4 4.7 GO:0038191 neuropilin binding(GO:0038191)
1.5 4.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 4.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 4.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 4.4 GO:0017124 SH3 domain binding(GO:0017124)
0.7 4.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 4.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
1.3 4.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 24.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 13.6 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 10.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 10.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 6.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 5.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 5.1 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 4.7 PID_IGF1_PATHWAY IGF1 pathway
0.1 3.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 2.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 2.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 2.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.3 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 2.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.1 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 2.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 1.6 PID_CONE_PATHWAY Visual signal transduction: Cones
0.1 1.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 5.2 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 5.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 4.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.4 4.7 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.4 4.6 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 4.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4 4.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.3 4.4 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.2 3.0 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 2.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.4 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 2.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 2.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.2 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.7 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)