Motif ID: Cbfb

Z-value: 0.449


Transcription factors associated with Cbfb:

Gene SymbolEntrez IDGene Name
Cbfb ENSMUSG00000031885.7 Cbfb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cbfbmm10_v2_chr8_+_105170668_1051706860.153.4e-01Click!


Activity profile for motif Cbfb.

activity profile for motif Cbfb


Sorted Z-values histogram for motif Cbfb

Sorted Z-values for motif Cbfb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cbfb

PNG image of the network

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Top targets:


Showing 1 to 20 of 31 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66801577 2.623 ENSMUST00000168589.1
 Sla
src-like adaptor
chr8_+_27260327 2.108 ENSMUST00000033880.5
 Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr19_-_50678642 1.628 ENSMUST00000072685.6
ENSMUST00000164039.2
 Sorcs1

VPS10 domain receptor protein SORCS 1

chr19_-_50678485 1.223 ENSMUST00000111756.3
 Sorcs1
VPS10 domain receptor protein SORCS 1
chr14_-_101729690 1.093 ENSMUST00000066461.3
 Gm9922
predicted gene 9922
chr14_+_101729907 1.079 ENSMUST00000100337.3
 Lmo7
LIM domain only 7
chr12_+_95692212 0.875 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr9_-_48480540 0.703 ENSMUST00000034524.3
 Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr2_+_72297895 0.585 ENSMUST00000144111.1
 Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr4_-_6990774 0.581 ENSMUST00000039987.3
 Tox
thymocyte selection-associated high mobility group box
chr2_+_35132194 0.446 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
 Cep110


centrosomal protein 110


chr2_+_164948219 0.399 ENSMUST00000017881.2
 Mmp9
matrix metallopeptidase 9
chr7_-_115824699 0.297 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr4_+_108847827 0.217 ENSMUST00000102738.2
 Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr15_+_99393219 0.150 ENSMUST00000159209.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr3_+_121291725 0.121 ENSMUST00000039442.7
 Alg14
asparagine-linked glycosylation 14
chr19_+_6061176 0.117 ENSMUST00000162726.3
 Znhit2
zinc finger, HIT domain containing 2
chr2_+_172393794 0.101 ENSMUST00000099061.2
ENSMUST00000103073.2
 Cass4

Cas scaffolding protein family member 4

chr2_+_32721055 0.087 ENSMUST00000074248.4
 Sh2d3c
SH2 domain containing 3C
chr15_+_99393610 0.063 ENSMUST00000159531.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.4 2.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)

Gene overrepresentation in cellular_component category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular_function category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 2.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.1 GO:0042805 actinin binding(GO:0042805)
0.1 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 2.1 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix