Motif ID: Cebpa_Cebpg

Z-value: 0.463

Transcription factors associated with Cebpa_Cebpg:

Gene SymbolEntrez IDGene Name
Cebpa ENSMUSG00000034957.9 Cebpa
Cebpg ENSMUSG00000056216.8 Cebpg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpamm10_v2_chr7_+_35119285_351193010.202.1e-01Click!
Cebpgmm10_v2_chr7_-_35056467_35056556-0.172.9e-01Click!


Activity profile for motif Cebpa_Cebpg.

activity profile for motif Cebpa_Cebpg


Sorted Z-values histogram for motif Cebpa_Cebpg

Sorted Z-values for motif Cebpa_Cebpg



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Top targets:


Showing 1 to 20 of 141 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_66219909 2.064 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr13_+_24614608 1.347 ENSMUST00000091694.3
 Fam65b
family with sequence similarity 65, member B
chr9_-_121495678 1.242 ENSMUST00000035120.4
 Cck
cholecystokinin
chr6_-_23248264 1.164 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr9_+_37367354 1.116 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr14_+_65971049 0.937 ENSMUST00000128539.1
 Clu
clusterin
chr14_+_65970610 0.926 ENSMUST00000127387.1
 Clu
clusterin
chr4_+_136143497 0.911 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chrX_-_162565514 0.894 ENSMUST00000154424.1
 Reps2
RALBP1 associated Eps domain containing protein 2
chr13_-_49309217 0.876 ENSMUST00000110087.2
 Fgd3
FYVE, RhoGEF and PH domain containing 3
chr13_-_117025505 0.849 ENSMUST00000022239.6
 Parp8
poly (ADP-ribose) polymerase family, member 8
chr1_-_22315792 0.836 ENSMUST00000164877.1
 Rims1
regulating synaptic membrane exocytosis 1
chr7_-_79149042 0.834 ENSMUST00000032825.8
ENSMUST00000107409.3
 Mfge8

milk fat globule-EGF factor 8 protein

chr12_+_74297474 0.795 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr15_-_88978958 0.768 ENSMUST00000042594.6
ENSMUST00000109368.1
 Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr14_+_65971164 0.753 ENSMUST00000144619.1
 Clu
clusterin
chr15_-_65014904 0.745 ENSMUST00000110100.2
 Gm21961
predicted gene, 21961
chr2_-_65567465 0.689 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567505 0.637 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr14_+_65970804 0.608 ENSMUST00000138191.1
 Clu
clusterin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4 2.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 1.3 GO:0046684 response to pyrethroid(GO:0046684)
0.2 1.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 1.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.9 GO:0030903 notochord development(GO:0030903)
0.2 0.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 0.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.8 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.5 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) action potential propagation(GO:0098870)
0.1 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.1 0.2 GO:0021759 globus pallidus development(GO:0021759)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.2 0.8 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:1990075 stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0051787 misfolded protein binding(GO:0051787)
0.3 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.8 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels