Motif ID: Cebpe

Z-value: 1.047


Transcription factors associated with Cebpe:

Gene SymbolEntrez IDGene Name
Cebpe ENSMUSG00000052435.6 Cebpe



Activity profile for motif Cebpe.

activity profile for motif Cebpe


Sorted Z-values histogram for motif Cebpe

Sorted Z-values for motif Cebpe



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpe

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 8.918 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr14_+_50944499 7.330 ENSMUST00000178092.1
 Pnp
purine-nucleoside phosphorylase
chr10_-_92165159 5.950 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr9_-_100506844 4.598 ENSMUST00000112874.3
 Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr16_-_22161450 4.505 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr10_-_45470201 3.567 ENSMUST00000079390.6
 Lin28b
lin-28 homolog B (C. elegans)
chr1_+_6487231 3.422 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr7_-_137314394 3.391 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr6_+_5390387 3.330 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr11_-_76399107 3.189 ENSMUST00000021204.3
 Nxn
nucleoredoxin
chr19_+_60144682 3.090 ENSMUST00000065383.4
 E330013P04Rik
RIKEN cDNA E330013P04 gene
chrX_+_112311334 3.047 ENSMUST00000026599.3
ENSMUST00000113415.1
 Apool

apolipoprotein O-like

chr12_-_10900296 2.966 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr17_+_21691860 2.841 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr4_-_117182623 2.832 ENSMUST00000065896.2
 Kif2c
kinesin family member 2C
chr6_+_56017489 2.711 ENSMUST00000052827.4
 Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr5_+_8056527 2.439 ENSMUST00000148633.1
 Sri
sorcin
chr1_+_146420434 2.422 ENSMUST00000163646.1
 Gm5263
predicted gene 5263
chr8_-_57487801 2.283 ENSMUST00000034022.3
 Sap30
sin3 associated polypeptide
chr7_+_67647405 2.280 ENSMUST00000032774.8
ENSMUST00000107471.1
 Ttc23

tetratricopeptide repeat domain 23


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 287 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 11.0 GO:0015671 oxygen transport(GO:0015671)
1.2 8.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
2.4 7.3 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 4.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.5 4.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 4.6 GO:0051028 mRNA transport(GO:0051028)
0.4 3.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 3.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 3.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.3 3.4 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 3.3 GO:0007052 mitotic spindle organization(GO:0007052)
0.2 3.0 GO:0042407 cristae formation(GO:0042407)
0.1 2.9 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.6 2.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 2.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 2.8 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.2 2.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.7 2.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 2.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 2.5 GO:0042462 eye photoreceptor cell development(GO:0042462)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 141 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 11.0 GO:0005833 hemoglobin complex(GO:0005833)
0.3 5.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 4.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 4.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.2 GO:0016607 nuclear speck(GO:0016607)
0.7 4.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 3.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 3.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.7 3.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 3.1 GO:0000776 kinetochore(GO:0000776)
0.3 3.0 GO:0061617 MICOS complex(GO:0061617)
0.1 2.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.5 GO:0005902 microvillus(GO:0005902)
0.8 2.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 2.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 2.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.4 GO:0000786 nucleosome(GO:0000786)
0.1 2.3 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 204 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 11.0 GO:0031721 hemoglobin alpha binding(GO:0031721)
3.0 9.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.8 4.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 4.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 4.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 3.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 3.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.4 3.0 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.3 2.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 2.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 2.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 2.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 2.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.3 2.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 2.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 2.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 5.8 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 5.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 3.6 PID_BARD1_PATHWAY BARD1 signaling events
0.1 3.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.4 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 2.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 2.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.2 1.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.2 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.0 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.8 9.0 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 6.9 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 6.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 5.4 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.3 4.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 4.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.3 REACTOME_DIABETES_PATHWAYS Genes involved in Diabetes pathways
0.1 3.0 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 2.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.9 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.8 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.7 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.7 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4