Motif ID: Cpeb1
Z-value: 1.400
Transcription factors associated with Cpeb1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Cpeb1 | ENSMUSG00000025586.10 | Cpeb1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Cpeb1 | mm10_v2_chr7_-_81454751_81454764 | 0.06 | 7.3e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 177 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 23.1 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
| 3.5 | 17.7 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 3.9 | 15.8 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 1.0 | 14.9 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 2.3 | 11.4 | GO:0015671 | oxygen transport(GO:0015671) |
| 2.2 | 10.8 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.2 | 9.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.5 | 9.1 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.8 | 8.7 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 2.1 | 8.4 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 1.9 | 5.6 | GO:0071649 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274) |
| 0.1 | 5.2 | GO:0051384 | response to glucocorticoid(GO:0051384) |
| 0.5 | 4.8 | GO:0090166 | Golgi disassembly(GO:0090166) regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.3 | 4.5 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.1 | 4.0 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.5 | 3.9 | GO:0021546 | rhombomere development(GO:0021546) |
| 0.7 | 3.7 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.7 | 3.5 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) |
| 0.3 | 3.5 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.3 | 3.3 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 82 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.7 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 16.5 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.1 | 15.3 | GO:0030426 | growth cone(GO:0030426) |
| 0.1 | 5.9 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 5.9 | GO:0005912 | adherens junction(GO:0005912) |
| 0.7 | 5.5 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 5.1 | GO:0005795 | Golgi stack(GO:0005795) |
| 1.2 | 4.8 | GO:0008623 | CHRAC(GO:0008623) |
| 0.8 | 4.8 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.0 | 4.4 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.2 | 4.1 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.4 | 3.9 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 3.5 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 3.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 3.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.6 | 3.0 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.5 | 2.8 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 2.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.3 | 2.7 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.3 | 2.7 | GO:0032982 | myosin filament(GO:0032982) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 122 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 35.0 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.6 | 16.8 | GO:0032183 | SUMO binding(GO:0032183) |
| 2.4 | 16.7 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.2 | 15.3 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 2.3 | 11.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 1.8 | 11.0 | GO:0019841 | retinol binding(GO:0019841) |
| 1.5 | 9.0 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 8.6 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 8.5 | GO:0008270 | zinc ion binding(GO:0008270) |
| 1.7 | 8.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 8.3 | GO:0016779 | nucleotidyltransferase activity(GO:0016779) |
| 0.3 | 6.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.3 | 5.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.3 | 5.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.3 | 5.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.2 | 5.1 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 4.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 4.0 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 3.9 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 3.5 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 34 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 18.1 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.2 | 8.8 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.2 | 8.7 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 6.8 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.1 | 6.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 6.4 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.2 | 6.2 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 5.2 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 3.7 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.2 | 3.3 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 3.2 | PID_P73PATHWAY | p73 transcription factor network |
| 0.1 | 3.1 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 2.8 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 2.1 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 2.1 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.0 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 1.9 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.3 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.1 | 1.0 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 1.0 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 53 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 16.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.2 | 5.7 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 5.6 | REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.3 | 5.2 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 5.1 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 4.0 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.3 | 3.7 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.4 | 3.3 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.0 | 3.2 | REACTOME_DIABETES_PATHWAYS | Genes involved in Diabetes pathways |
| 0.1 | 3.0 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 2.8 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 2.8 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.7 | 2.1 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.1 | 2.0 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.1 | 1.8 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 1.8 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 1.8 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.2 | 1.7 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.1 | 1.7 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.1 | 1.7 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
