Motif ID: Cxxc1

Z-value: 0.569


Transcription factors associated with Cxxc1:

Gene SymbolEntrez IDGene Name
Cxxc1 ENSMUSG00000024560.6 Cxxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cxxc1mm10_v2_chr18_+_74216118_74216145-0.269.7e-02Click!


Activity profile for motif Cxxc1.

activity profile for motif Cxxc1


Sorted Z-values histogram for motif Cxxc1

Sorted Z-values for motif Cxxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cxxc1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 53 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_89302545 6.067 ENSMUST00000061728.3
 Nog
noggin
chr7_-_49636847 2.657 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr11_-_69921057 2.491 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
 Eif5a


eukaryotic translation initiation factor 5A


chr11_-_69920892 1.951 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
 Eif5a


eukaryotic translation initiation factor 5A


chr19_-_36919606 1.550 ENSMUST00000057337.7
 Fgfbp3
fibroblast growth factor binding protein 3
chr19_-_4439388 1.527 ENSMUST00000117462.1
ENSMUST00000048197.3
 Rhod

ras homolog gene family, member D

chr19_+_38931008 1.486 ENSMUST00000145051.1
 Hells
helicase, lymphoid specific
chr12_+_110279228 1.453 ENSMUST00000097228.4
 Dio3
deiodinase, iodothyronine type III
chr11_-_68386974 1.390 ENSMUST00000135141.1
 Ntn1
netrin 1
chr17_-_14203695 1.345 ENSMUST00000053218.5
 Dact2
dapper homolog 2, antagonist of beta-catenin (xenopus)
chr3_-_8964037 1.212 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr1_-_124045523 1.162 ENSMUST00000112606.1
 Dpp10
dipeptidylpeptidase 10
chr10_+_50895651 1.130 ENSMUST00000020071.3
 Sim1
single-minded homolog 1 (Drosophila)
chr5_-_4758216 1.029 ENSMUST00000054294.4
 Fzd1
frizzled homolog 1 (Drosophila)
chr5_-_125389177 1.023 ENSMUST00000108707.2
 Ubc
ubiquitin C
chr3_-_101307079 0.980 ENSMUST00000097146.2
 Gm10355
predicted gene 10355
chr2_+_112239468 0.924 ENSMUST00000028554.3
 Lpcat4
lysophosphatidylcholine acyltransferase 4
chr10_+_128058974 0.922 ENSMUST00000084771.2
 Ptges3
prostaglandin E synthase 3 (cytosolic)
chr1_-_124045247 0.903 ENSMUST00000112603.2
 Dpp10
dipeptidylpeptidase 10
chr8_+_92357787 0.889 ENSMUST00000034184.10
 Irx5
Iroquois related homeobox 5 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 6.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.9 5.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 2.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 2.1 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.2 1.7 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 1.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 1.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 1.5 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.0 1.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.2 1.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 1.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.3 1.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.9 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.7 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.5 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 5.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.5 GO:1990047 spindle matrix(GO:1990047)
0.1 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0001740 Barr body(GO:0001740)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.1 GO:0019955 cytokine binding(GO:0019955)
0.3 5.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 2.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 1.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.6 GO:0019843 rRNA binding(GO:0019843)
0.0 1.5 GO:0002020 protease binding(GO:0002020)
0.1 1.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 0.9 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.1 0.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.1 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.2 5.2 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.6 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.4 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.2 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.9 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels