Motif ID: Dbp

Z-value: 0.826


Transcription factors associated with Dbp:

Gene SymbolEntrez IDGene Name
Dbp ENSMUSG00000059824.4 Dbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbpmm10_v2_chr7_+_45705518_45705624-0.182.5e-01Click!


Activity profile for motif Dbp.

activity profile for motif Dbp


Sorted Z-values histogram for motif Dbp

Sorted Z-values for motif Dbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Dbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_66386968 4.535 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr10_+_123264076 4.364 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr5_+_150259922 3.944 ENSMUST00000087204.5
 Fry
furry homolog (Drosophila)
chr6_-_23248264 3.112 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_+_65845833 2.830 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr15_+_4375462 2.661 ENSMUST00000061925.4
 Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr12_+_61523889 2.645 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr10_+_85386813 2.628 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chrX_-_165327376 2.511 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr2_+_65845767 2.468 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr14_-_93888732 2.400 ENSMUST00000068992.2
 Pcdh9
protocadherin 9
chrX_-_43167817 2.399 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr16_+_7069825 2.350 ENSMUST00000056416.7
 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr9_-_49798905 2.273 ENSMUST00000114476.2
 Ncam1
neural cell adhesion molecule 1
chr7_+_57591147 2.120 ENSMUST00000039697.7
 Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chrX_+_120290259 2.119 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
 Pcdh11x


protocadherin 11 X-linked


chr2_+_169632996 2.099 ENSMUST00000109159.2
 Tshz2
teashirt zinc finger family member 2
chr1_-_64122256 2.059 ENSMUST00000135075.1
 Klf7
Kruppel-like factor 7 (ubiquitous)
chr16_-_34513944 2.025 ENSMUST00000151491.1
ENSMUST00000114960.2
 Kalrn

kalirin, RhoGEF kinase

chr12_-_83487708 2.003 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.4 4.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.4 4.2 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.4 3.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.4 3.9 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.5 3.7 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.4 3.6 GO:0071420 cellular response to histamine(GO:0071420)
0.1 3.6 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 3.3 GO:0007416 synapse assembly(GO:0007416)
0.5 3.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 2.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.9 2.8 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.2 2.8 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2 2.6 GO:0021540 corpus callosum morphogenesis(GO:0021540) corticospinal tract morphogenesis(GO:0021957)
0.1 2.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.4 2.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 2.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.7 2.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.0 2.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 10.3 GO:0030427 site of polarized growth(GO:0030427)
0.1 9.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 6.2 GO:0071565 nBAF complex(GO:0071565)
0.1 5.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 5.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 4.8 GO:0043198 dendritic shaft(GO:0043198)
0.5 4.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 4.5 GO:0032279 asymmetric synapse(GO:0032279)
0.1 3.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 3.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.9 GO:0034399 nuclear periphery(GO:0034399)
0.1 2.5 GO:0034707 chloride channel complex(GO:0034707)
0.6 2.4 GO:0031673 H zone(GO:0031673)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.0 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.4 GO:0042589 zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 5.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 4.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.6 4.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 4.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 4.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 4.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.3 3.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 3.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 3.3 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.3 3.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.8 2.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 2.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 2.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.2 2.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.1 GO:0004386 helicase activity(GO:0004386)
0.5 2.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 2.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.1 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 4.2 PID_FGF_PATHWAY FGF signaling pathway
0.1 4.1 PID_LKB1_PATHWAY LKB1 signaling events
0.1 3.7 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 3.6 ST_ADRENERGIC Adrenergic Pathway
0.0 2.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.8 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.3 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.2 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.8 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.6 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 8.0 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.3 7.3 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 5.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 5.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 4.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.6 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.3 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 2.0 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.8 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.8 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.1 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.1 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME_ION_CHANNEL_TRANSPORT Genes involved in Ion channel transport
0.0 0.7 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling