Motif ID: Ebf1

Z-value: 1.205


Transcription factors associated with Ebf1:

Gene SymbolEntrez IDGene Name
Ebf1 ENSMUSG00000078561.3 Ebf1
Ebf1 ENSMUSG00000057098.8 Ebf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf1mm10_v2_chr11_+_44617310_446173360.019.5e-01Click!


Activity profile for motif Ebf1.

activity profile for motif Ebf1


Sorted Z-values histogram for motif Ebf1

Sorted Z-values for motif Ebf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_34000257 3.551 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
 H2-K1




histocompatibility 2, K1, K region




chr16_+_92498122 3.421 ENSMUST00000023670.3
 Clic6
chloride intracellular channel 6
chr7_-_30973464 3.223 ENSMUST00000001279.8
 Lsr
lipolysis stimulated lipoprotein receptor
chr7_-_30973367 2.849 ENSMUST00000108116.3
 Lsr
lipolysis stimulated lipoprotein receptor
chr9_+_108479849 2.622 ENSMUST00000065014.4
 Lamb2
laminin, beta 2
chr7_-_142899985 2.473 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr5_+_42067960 2.419 ENSMUST00000087332.4
 Gm16223
predicted gene 16223
chr9_-_37433138 2.394 ENSMUST00000115038.1
 Robo3
roundabout homolog 3 (Drosophila)
chr7_-_30973399 2.336 ENSMUST00000098553.4
ENSMUST00000147431.1
 Lsr

lipolysis stimulated lipoprotein receptor

chr2_+_131186942 2.320 ENSMUST00000028804.8
ENSMUST00000079857.8
 Cdc25b

cell division cycle 25B

chr19_-_45742873 2.292 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8


chr2_+_84840612 2.238 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1
chr5_+_136967859 2.164 ENSMUST00000001790.5
 Cldn15
claudin 15
chr16_+_17489639 2.115 ENSMUST00000023448.6
 Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr10_+_108332173 2.072 ENSMUST00000095313.3
 Pawr
PRKC, apoptosis, WT1, regulator
chr7_-_110061319 2.070 ENSMUST00000098110.2
 AA474408
expressed sequence AA474408
chr7_+_4119525 2.043 ENSMUST00000119661.1
ENSMUST00000129423.1
 Ttyh1

tweety homolog 1 (Drosophila)

chr17_+_34597852 1.908 ENSMUST00000174496.2
ENSMUST00000015596.3
ENSMUST00000173992.1
 Ager


advanced glycosylation end product-specific receptor


chr14_-_34374617 1.883 ENSMUST00000023826.4
 Sncg
synuclein, gamma
chr7_+_4119556 1.882 ENSMUST00000079415.5
 Ttyh1
tweety homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 723 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 8.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.7 5.3 GO:2001198 regulation of dendritic cell differentiation(GO:2001198)
0.9 4.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 4.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 4.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.0 4.0 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.5 3.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.7 3.5 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.2 3.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.8 3.3 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.7 3.3 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.6 3.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.5 2.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 2.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 2.8 GO:0046677 response to antibiotic(GO:0046677)
0.1 2.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.4 2.7 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 2.6 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.8 2.5 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.8 2.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 281 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 11.0 GO:0005615 extracellular space(GO:0005615)
0.0 8.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
1.4 8.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 8.4 GO:0005581 collagen trimer(GO:0005581)
0.0 7.3 GO:0031012 extracellular matrix(GO:0031012)
0.4 6.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.5 6.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.8 5.0 GO:0043256 laminin complex(GO:0043256)
0.1 4.8 GO:0000791 euchromatin(GO:0000791)
0.1 4.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.2 GO:0022626 cytosolic ribosome(GO:0022626)
1.3 3.9 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.3 3.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 3.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.8 3.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 3.2 GO:0005604 basement membrane(GO:0005604)
1.0 3.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 3.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 446 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 11.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 7.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 7.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 6.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 6.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.2 5.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 5.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 4.6 GO:0005178 integrin binding(GO:0005178)
0.1 4.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 4.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.0 3.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 3.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 3.7 GO:0005507 copper ion binding(GO:0005507)
0.0 3.7 GO:0008201 heparin binding(GO:0008201)
0.9 3.6 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.2 3.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 3.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.1 3.4 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 3.4 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 8.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 6.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 6.1 PID_FGF_PATHWAY FGF signaling pathway
0.1 6.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.6 5.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.3 NABA_COLLAGENS Genes encoding collagen proteins
0.1 4.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 4.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 4.0 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.4 3.7 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.4 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 3.3 PID_P73PATHWAY p73 transcription factor network
0.0 3.0 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 2.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.4 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 2.3 PID_ALK1_PATHWAY ALK1 signaling events
0.1 2.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 147 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 14.2 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 8.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 7.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 6.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 6.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 5.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.2 3.6 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 3.6 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 3.5 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 3.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.4 3.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 3.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 3.1 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 3.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 3.0 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.2 2.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 2.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.9 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 2.8 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.5 2.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators