Motif ID: Elf5

Z-value: 0.771


Transcription factors associated with Elf5:

Gene SymbolEntrez IDGene Name
Elf5 ENSMUSG00000027186.8 Elf5



Activity profile for motif Elf5.

activity profile for motif Elf5


Sorted Z-values histogram for motif Elf5

Sorted Z-values for motif Elf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 3.451 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr17_+_22689771 1.876 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr1_-_79440039 1.788 ENSMUST00000049972.4
 Scg2
secretogranin II
chr18_+_62548911 1.492 ENSMUST00000055725.4
ENSMUST00000162365.1
 Spink10

serine peptidase inhibitor, Kazal type 10

chr2_-_12419456 1.489 ENSMUST00000154899.1
ENSMUST00000028105.6
 Fam188a

family with sequence similarity 188, member A

chr8_+_62951361 1.362 ENSMUST00000119068.1
 Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr11_-_53430417 1.339 ENSMUST00000109019.1
 Uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
chr11_+_96034885 1.322 ENSMUST00000006217.3
ENSMUST00000107700.3
 Snf8

SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)

chr3_+_95217417 1.302 ENSMUST00000181819.1
 Gm16740
predicted gene, 16740
chr14_-_55671873 1.296 ENSMUST00000163750.1
ENSMUST00000010520.8
 Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr5_+_122391878 1.269 ENSMUST00000102525.4
 Arpc3
actin related protein 2/3 complex, subunit 3
chr2_+_104886318 1.253 ENSMUST00000111114.1
 Ccdc73
coiled-coil domain containing 73
chr2_+_61711694 1.236 ENSMUST00000028278.7
 Psmd14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr7_+_105640448 1.210 ENSMUST00000058333.3
 Timm10b
translocase of inner mitochondrial membrane 10B
chr11_+_32276400 1.207 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr15_+_98167806 1.186 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr4_+_118409331 1.158 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
 Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr14_-_76556662 1.151 ENSMUST00000064517.7
 Serp2
stress-associated endoplasmic reticulum protein family member 2
chr4_+_44012661 1.142 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
 Clta


clathrin, light polypeptide (Lca)


chr5_+_29735940 1.132 ENSMUST00000114839.1
 Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 445 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 3.7 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.6 3.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 3.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 2.7 GO:0045116 protein neddylation(GO:0045116)
0.2 2.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 2.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 2.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 2.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 2.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 2.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4 2.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 2.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 2.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.5 1.9 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 1.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.9 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.3 1.8 GO:0021539 subthalamus development(GO:0021539)
0.0 1.8 GO:0032543 mitochondrial translation(GO:0032543)
0.3 1.7 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 213 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 7.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 5.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 5.2 GO:0005685 U1 snRNP(GO:0005685)
0.1 3.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 3.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.6 2.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 2.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 2.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 2.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 2.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.7 2.1 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.2 2.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.4 2.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.9 GO:0031045 dense core granule(GO:0031045)
0.6 1.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 294 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 4.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 3.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 3.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 3.0 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 2.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.3 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.3 2.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 2.1 GO:0031386 protein tag(GO:0031386)
0.1 2.1 GO:0031489 myosin V binding(GO:0031489)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.6 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.3 1.5 GO:0035614 snRNA stem-loop binding(GO:0035614)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.9 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.8 PID_P73PATHWAY p73 transcription factor network
0.1 1.7 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 1.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.0 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 1.0 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 0.8 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.8 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.7 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.7 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.6 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.7 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 8.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 7.5 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 6.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 5.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.3 3.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.8 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 2.1 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.9 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.7 REACTOME_APOPTOTIC_EXECUTION_PHASE Genes involved in Apoptotic execution phase
0.1 1.6 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.5 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening