ISMARA results: Ep300

Motif ID: Ep300

Z-value: 0.565

Transcription factors associated with Ep300:

Gene Symbol	Entrez ID	Gene Name
Ep300	ENSMUSG00000055024.6	Ep300

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Ep300	mm10_v2_chr15_+_81586206_81586250	-0.11	5.1e-01	Click!

View svg image
View png image

Top targets:

Search:

Show entries

Showing 1 to 20 of 200 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_+_98348404	3.124	ENSMUST00000078694.6	Ppp1r1b	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_+_96522342	2.160	ENSMUST00000129737.1	Tenm4	teneurin transmembrane protein 4
chr4_+_125490688	2.026	ENSMUST00000030676.7	Grik3	glutamate receptor, ionotropic, kainate 3
chr8_-_84800344	1.965	ENSMUST00000099070.3	Nfix	nuclear factor I/X
chr6_+_99692679	1.736	ENSMUST00000101122.1	Gpr27	G protein-coupled receptor 27
chr10_+_58813359	1.210	ENSMUST00000135526.2 ENSMUST00000153031.1	Sh3rf3	SH3 domain containing ring finger 3
chr2_+_163602331	1.208	ENSMUST00000152135.1	Ttpal	tocopherol (alpha) transfer protein-like
chr16_-_52452465	1.199	ENSMUST00000170035.1 ENSMUST00000164728.1	Alcam	activated leukocyte cell adhesion molecule
chr9_-_29411736	1.064	ENSMUST00000115236.1	Ntm	neurotrimin
chr19_-_7105729	1.010	ENSMUST00000113383.2	Flrt1	fibronectin leucine rich transmembrane protein 1
chr19_+_23758819	0.942	ENSMUST00000025830.7	Apba1	amyloid beta (A4) precursor protein binding, family A, member 1
chr16_-_52452654	0.889	ENSMUST00000168071.1	Alcam	activated leukocyte cell adhesion molecule
chr1_-_87573825	0.886	ENSMUST00000068681.5	Ngef	neuronal guanine nucleotide exchange factor
chr11_+_97415527	0.831	ENSMUST00000121799.1	Arhgap23	Rho GTPase activating protein 23
chr2_+_25054355	0.826	ENSMUST00000100334.4 ENSMUST00000152122.1 ENSMUST00000116574.3 ENSMUST00000006646.8	Nsmf	NMDA receptor synaptonuclear signaling and neuronal migration factor
chr2_-_31845925	0.806	ENSMUST00000028188.7	Fibcd1	fibrinogen C domain containing 1
chr7_-_132317198	0.786	ENSMUST00000080215.5	Chst15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr2_+_25054396	0.784	ENSMUST00000102931.4 ENSMUST00000074422.7 ENSMUST00000132172.1 ENSMUST00000114388.1 ENSMUST00000114386.1	Nsmf	NMDA receptor synaptonuclear signaling and neuronal migration factor
chr6_-_136173492	0.780	ENSMUST00000111905.1	Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr8_+_112570043	0.767	ENSMUST00000034225.6 ENSMUST00000118171.1	Cntnap4	contactin associated protein-like 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Showing 1 to 20 of 82 entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.5	2.2	GO:0032289	central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1	2.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.2	2.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	2.0	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6	1.7	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1	1.7	GO:0035635	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.4	1.6	GO:0099527	postsynapse to nucleus signaling pathway(GO:0099527)
0.0	1.4	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.2	1.1	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	1.0	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	1.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.9	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2	0.8	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1	0.8	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.8	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.0	0.8	GO:0019319	hexose biosynthetic process(GO:0019319)
0.1	0.7	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.7	GO:0005513	detection of calcium ion(GO:0005513)
0.1	0.7	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)

Gene overrepresentation in cellular_component category:

Search:

Show entries

Showing 1 to 20 of 36 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	2.0	GO:0097440	apical dendrite(GO:0097440)
0.0	2.0	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	1.9	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	1.7	GO:0032584	growth cone membrane(GO:0032584)
0.0	1.5	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.3	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	1.1	GO:0097443	sorting endosome(GO:0097443)
0.1	1.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	1.0	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	0.8	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.8	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.6	GO:1990130	Iml1 complex(GO:1990130)
0.1	0.5	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1	0.5	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.5	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.5	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.4	GO:0044300	cerebellar mossy fiber(GO:0044300)

Gene overrepresentation in molecular_function category:

Search:

Show entries

Showing 1 to 20 of 55 entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0031752	D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.4	2.0	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0	1.8	GO:0017124	SH3 domain binding(GO:0017124)
0.0	1.6	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.2	1.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	1.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	1.3	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.1	1.0	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	1.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.3	0.8	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2	0.8	GO:0008061	chitin binding(GO:0008061)
0.1	0.8	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.2	0.7	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.7	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.7	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.7	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.7	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.7	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	0.5	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)

Gene overrepresentation in C2:CP category:

Search:

Show entries

Showing 1 to 14 of 14 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.3	PID_CDC42_REG_PATHWAY	Regulation of CDC42 activity
0.0	2.0	PID_CDC42_PATHWAY	CDC42 signaling events
0.0	1.3	PID_AR_NONGENOMIC_PATHWAY	Nongenotropic Androgen signaling
0.0	0.8	PID_TRAIL_PATHWAY	TRAIL signaling pathway
0.0	0.7	PID_ERBB1_INTERNALIZATION_PATHWAY	Internalization of ErbB1
0.0	0.7	PID_REELIN_PATHWAY	Reelin signaling pathway
0.0	0.7	PID_NFAT_TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.5	ST_INTERFERON_GAMMA_PATHWAY	Interferon gamma pathway.
0.0	0.5	PID_S1P_S1P3_PATHWAY	S1P3 pathway
0.0	0.5	PID_CIRCADIAN_PATHWAY	Circadian rhythm pathway
0.0	0.5	PID_ATM_PATHWAY	ATM pathway
0.0	0.4	PID_IL3_PATHWAY	IL3-mediated signaling events
0.1	0.3	PID_S1P_S1P2_PATHWAY	S1P2 pathway
0.0	0.1	ST_IL_13_PATHWAY	Interleukin 13 (IL-13) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Showing 1 to 20 of 25 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.4	REACTOME_DARPP_32_EVENTS	Genes involved in DARPP-32 events
0.1	2.1	REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	2.1	REACTOME_L1CAM_INTERACTIONS	Genes involved in L1CAM interactions
0.1	2.0	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	2.0	REACTOME_POTASSIUM_CHANNELS	Genes involved in Potassium Channels
0.0	1.3	REACTOME_HS_GAG_BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	1.1	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	Genes involved in NRAGE signals death through JNK
0.1	1.0	REACTOME_ZINC_TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.8	REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.7	REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.7	REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME_BASIGIN_INTERACTIONS	Genes involved in Basigin interactions
0.0	0.7	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.6	REACTOME_PURINE_SALVAGE	Genes involved in Purine salvage
0.0	0.6	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.5	REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.5	REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	0.3	REACTOME_GLYCOPROTEIN_HORMONES	Genes involved in Glycoprotein hormones