Motif ID: Etv4
Z-value: 0.467

Transcription factors associated with Etv4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Etv4 | ENSMUSG00000017724.8 | Etv4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Etv4 | mm10_v2_chr11_-_101785252_101785371 | -0.10 | 5.3e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 218 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.9 | GO:0032526 | response to retinoic acid(GO:0032526) |
0.1 | 1.7 | GO:1901898 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.2 | 1.6 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.1 | 1.6 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.2 | 1.5 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.0 | 1.4 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.1 | 1.3 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
0.2 | 1.2 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
0.1 | 1.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.3 | 1.0 | GO:1905065 | positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
0.2 | 1.0 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.1 | 1.0 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
0.1 | 1.0 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.0 | 1.0 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.2 | 0.9 | GO:0014042 | positive regulation of neuron maturation(GO:0014042) |
0.2 | 0.9 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
0.2 | 0.9 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.0 | 0.9 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
0.0 | 0.9 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
0.0 | 0.9 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 97 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.4 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 1.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 1.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.2 | 1.5 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.4 | 1.3 | GO:1990257 | piccolo-bassoon transport vesicle(GO:1990257) |
0.2 | 1.2 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
0.0 | 1.2 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.1 | 1.1 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 1.1 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.0 | 1.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.2 | 0.9 | GO:0097443 | sorting endosome(GO:0097443) |
0.1 | 0.9 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 0.9 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.9 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.1 | 0.8 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.8 | GO:0001891 | phagocytic cup(GO:0001891) |
0.1 | 0.7 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.1 | 0.7 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.1 | 0.7 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.0 | 0.7 | GO:0030673 | axolemma(GO:0030673) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 136 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 2.0 | GO:0008083 | growth factor activity(GO:0008083) |
0.1 | 1.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 1.7 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 1.7 | GO:0030276 | clathrin binding(GO:0030276) |
0.1 | 1.5 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 1.4 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.1 | 1.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.1 | 1.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.2 | 1.2 | GO:0097643 | amylin receptor activity(GO:0097643) |
0.0 | 1.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 1.1 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 1.1 | GO:0000149 | SNARE binding(GO:0000149) |
0.0 | 0.9 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.0 | 0.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.2 | 0.8 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.0 | 0.8 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.8 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
0.2 | 0.7 | GO:0071209 | U7 snRNA binding(GO:0071209) |
0.1 | 0.7 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 26 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.5 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.0 | 2.3 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.7 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.0 | 1.3 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 1.1 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 0.9 | PID_ARF_3PATHWAY | Arf1 pathway |
0.0 | 0.9 | PID_GMCSF_PATHWAY | GMCSF-mediated signaling events |
0.0 | 0.7 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 0.6 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.0 | 0.6 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.5 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.5 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 0.4 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.4 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.0 | 0.4 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.4 | PID_HIV_NEF_PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
0.0 | 0.4 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.4 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 0.3 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
0.0 | 0.3 | ST_B_CELL_ANTIGEN_RECEPTOR | B Cell Antigen Receptor |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 43 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.3 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 1.9 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.0 | 1.9 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.1 | 1.2 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.1 | 1.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.1 | 1.2 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.0 | 1.1 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 1.0 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 1.0 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.0 | 0.9 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 0.9 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 0.8 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.8 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.1 | 0.7 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.0 | 0.7 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.7 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.7 | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | Genes involved in Formation of RNA Pol II elongation complex |
0.0 | 0.6 | REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY | Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
0.0 | 0.6 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.0 | 0.5 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |