Motif ID: Foxf2

Z-value: 0.635


Transcription factors associated with Foxf2:

Gene SymbolEntrez IDGene Name
Foxf2 ENSMUSG00000038402.2 Foxf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf2mm10_v2_chr13_+_31625802_316258160.124.5e-01Click!


Activity profile for motif Foxf2.

activity profile for motif Foxf2


Sorted Z-values histogram for motif Foxf2

Sorted Z-values for motif Foxf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 100 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66969616 6.021 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr6_-_148444336 3.046 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr8_-_84773381 2.233 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr4_+_101507947 1.750 ENSMUST00000149047.1
ENSMUST00000106929.3
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr7_+_82175156 1.451 ENSMUST00000180243.1
 Sh3gl3
SH3-domain GRB2-like 3
chr7_+_30291941 1.372 ENSMUST00000144508.1
 Clip3
CAP-GLY domain containing linker protein 3
chr10_+_60106452 1.369 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr4_+_101507855 1.364 ENSMUST00000038207.5
 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr16_-_34263179 1.357 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr1_-_87573825 1.347 ENSMUST00000068681.5
 Ngef
neuronal guanine nucleotide exchange factor
chr16_-_22439570 1.319 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr12_-_112511136 1.236 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr1_+_179546303 1.177 ENSMUST00000040706.8
 Cnst
consortin, connexin sorting protein
chr7_-_4844665 1.165 ENSMUST00000066041.5
ENSMUST00000172377.1
 Shisa7

shisa homolog 7 (Xenopus laevis)

chr1_+_34005872 1.091 ENSMUST00000182296.1
 Dst
dystonin
chr16_+_91269759 1.073 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr7_+_30291659 1.019 ENSMUST00000014065.8
ENSMUST00000150892.1
ENSMUST00000126216.1
 Clip3


CAP-GLY domain containing linker protein 3


chr2_+_112265809 0.869 ENSMUST00000110991.2
 Slc12a6
solute carrier family 12, member 6
chr16_-_34262945 0.857 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr8_+_58912257 0.818 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 6.0 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.5 3.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.5 2.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 2.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.3 2.2 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 2.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4 1.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 1.2 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.3 0.8 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.8 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 6.5 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 1.1 GO:0031673 H zone(GO:0031673)
0.3 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.8 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.5 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.4 2.4 GO:0097001 ceramide binding(GO:0097001)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 1.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.2 GO:0071253 connexin binding(GO:0071253)
0.0 1.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 0.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0005118 sevenless binding(GO:0005118)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)

Gene overrepresentation in C2:CP category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.5 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 3.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.8 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival