Motif ID: Foxj3_Tbl1xr1

Z-value: 1.064

Transcription factors associated with Foxj3_Tbl1xr1:

Gene SymbolEntrez IDGene Name
Foxj3 ENSMUSG00000032998.10 Foxj3
Tbl1xr1 ENSMUSG00000027630.8 Tbl1xr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj3mm10_v2_chr4_+_119539652_119539698-0.192.2e-01Click!
Tbl1xr1mm10_v2_chr3_+_22076644_22076681-0.086.0e-01Click!


Activity profile for motif Foxj3_Tbl1xr1.

activity profile for motif Foxj3_Tbl1xr1


Sorted Z-values histogram for motif Foxj3_Tbl1xr1

Sorted Z-values for motif Foxj3_Tbl1xr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxj3_Tbl1xr1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144893127 3.433 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_144893077 3.330 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr8_-_84773381 3.310 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr4_+_144892813 3.250 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr5_-_135251209 3.098 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)
chr7_-_103827922 2.985 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr6_+_141524379 2.870 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr19_+_55741810 2.287 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr7_-_120202104 2.158 ENSMUST00000033198.5
 Crym
crystallin, mu
chr13_-_23430826 2.090 ENSMUST00000153753.1
ENSMUST00000141543.1
 C230035I16Rik

RIKEN cDNA C230035I16 gene

chr6_+_138140298 2.076 ENSMUST00000008684.4
 Mgst1
microsomal glutathione S-transferase 1
chr9_+_115909455 2.072 ENSMUST00000119291.1
ENSMUST00000069651.6
 Gadl1

glutamate decarboxylase-like 1

chr10_-_111997204 2.039 ENSMUST00000074805.5
 Glipr1
GLI pathogenesis-related 1 (glioma)
chr7_+_66365905 1.842 ENSMUST00000107486.1
 Gm10974
predicted gene 10974
chr10_-_85957775 1.811 ENSMUST00000001834.3
 Rtcb
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr10_+_57784859 1.796 ENSMUST00000020024.5
 Fabp7
fatty acid binding protein 7, brain
chr3_-_116968969 1.785 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr14_+_116925291 1.716 ENSMUST00000078849.4
 Gpc6
glypican 6
chr1_-_163313661 1.698 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
 Prrx1


paired related homeobox 1


chr15_+_3270767 1.696 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 995 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 8.6 GO:0042572 retinol metabolic process(GO:0042572)
0.7 5.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 5.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 3.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.9 3.5 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.1 3.3 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 3.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 3.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.0 3.1 GO:1990523 bone regeneration(GO:1990523)
0.4 3.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 3.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 3.0 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 2.8 GO:0048664 neuron fate determination(GO:0048664)
0.1 2.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.8 GO:0032543 mitochondrial translation(GO:0032543)
0.2 2.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 2.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.6 2.3 GO:0043490 malate-aspartate shuttle(GO:0043490)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 314 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 9.4 GO:0070469 respiratory chain(GO:0070469)
0.1 8.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 7.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 6.7 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 6.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 6.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
1.5 6.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 5.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 4.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 4.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 4.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 3.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.2 GO:0031527 filopodium membrane(GO:0031527)
0.2 2.9 GO:0098644 complex of collagen trimers(GO:0098644)
0.2 2.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 2.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 2.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 2.4 GO:0005685 U1 snRNP(GO:0005685)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 536 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.5 GO:0003735 structural constituent of ribosome(GO:0003735)
1.5 10.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 6.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.5 6.1 GO:0031720 haptoglobin binding(GO:0031720)
0.3 5.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 4.7 GO:0005504 fatty acid binding(GO:0005504)
0.2 4.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 4.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 3.9 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 3.8 GO:0008083 growth factor activity(GO:0008083)
0.2 3.6 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 3.4 GO:0001848 complement binding(GO:0001848)
0.0 3.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 3.0 GO:0071837 HMG box domain binding(GO:0071837)
0.7 2.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.4 2.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 2.8 GO:0017166 vinculin binding(GO:0017166)
0.1 2.7 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.6 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.4 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 6.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.8 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 5.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 5.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 5.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 4.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 4.4 NABA_CORE_MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 3.9 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.3 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 3.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 2.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 2.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 1.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.5 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.5 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 137 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 16.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 6.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 5.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 4.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 4.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 4.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 4.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 3.8 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 3.8 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 3.8 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 3.5 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 3.4 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 3.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 2.9 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 2.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.8 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 2.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER