Motif ID: Foxn1

Z-value: 0.554


Transcription factors associated with Foxn1:

Gene SymbolEntrez IDGene Name
Foxn1 ENSMUSG00000002057.4 Foxn1



Activity profile for motif Foxn1.

activity profile for motif Foxn1


Sorted Z-values histogram for motif Foxn1

Sorted Z-values for motif Foxn1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxn1

PNG image of the network

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Top targets:


Showing 1 to 20 of 114 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_77135513 1.278 ENSMUST00000168779.1
 2210408I21Rik
RIKEN cDNA 2210408I21 gene
chrX_-_111463103 1.084 ENSMUST00000137712.2
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chrX_+_151803642 1.016 ENSMUST00000156616.2
 Huwe1
HECT, UBA and WWE domain containing 1
chr6_-_32588192 1.014 ENSMUST00000115096.2
 Plxna4
plexin A4
chr9_+_70207342 1.009 ENSMUST00000034745.7
 Myo1e
myosin IE
chr19_+_46152505 0.992 ENSMUST00000026254.7
 Gbf1
golgi-specific brefeldin A-resistance factor 1
chr1_-_155099630 0.968 ENSMUST00000055322.4
 Ier5
immediate early response 5
chr18_-_37935378 0.942 ENSMUST00000025337.7
 Diap1
diaphanous homolog 1 (Drosophila)
chr17_+_6106464 0.929 ENSMUST00000142030.1
 Tulp4
tubby like protein 4
chr9_-_75683992 0.924 ENSMUST00000034699.6
 Scg3
secretogranin III
chr6_+_38433913 0.903 ENSMUST00000160583.1
 Ubn2
ubinuclein 2
chr6_+_149408973 0.859 ENSMUST00000086829.4
ENSMUST00000111513.2
 Bicd1

bicaudal D homolog 1 (Drosophila)

chr14_+_63606491 0.771 ENSMUST00000119973.2
 Xkr6
X Kell blood group precursor related family member 6 homolog
chr3_-_116007399 0.744 ENSMUST00000067485.3
 Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr10_+_19934472 0.685 ENSMUST00000095806.3
ENSMUST00000120259.1
 Map3k5

mitogen-activated protein kinase kinase kinase 5

chr13_-_77135416 0.681 ENSMUST00000159462.1
ENSMUST00000151524.2
 Ankrd32

ankyrin repeat domain 32

chrX_-_111463149 0.677 ENSMUST00000096348.3
ENSMUST00000113428.2
 Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr11_+_30771726 0.673 ENSMUST00000041231.7
 Psme4
proteasome (prosome, macropain) activator subunit 4
chr18_+_60526194 0.671 ENSMUST00000025505.5
 Dctn4
dynactin 4
chr11_+_67455339 0.652 ENSMUST00000108681.1
 Gas7
growth arrest specific 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.4 1.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.6 GO:0006284 base-excision repair(GO:0006284)
0.3 1.0 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 1.0 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 1.0 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 1.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.3 0.9 GO:1901608 dense core granule localization(GO:0032253) cellular response to isoquinoline alkaloid(GO:0071317) regulation of vesicle transport along microtubule(GO:1901608) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.3 0.9 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.0 0.9 GO:0061512 protein localization to cilium(GO:0061512)
0.3 0.8 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.8 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.2 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.7 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.7 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 0.6 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0001650 fibrillar center(GO:0001650)
0.2 1.0 GO:0032437 cuticular plate(GO:0032437)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.9 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.9 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.8 GO:0000974 Prp19 complex(GO:0000974)
0.2 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.2 0.6 GO:0044753 amphisome(GO:0044753)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916) catenin-TCF7L2 complex(GO:0071664)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 0.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 0.9 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.2 0.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 0.5 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in C2:CP category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.0 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.7 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.6 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.2 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 1.0 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.0 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.9 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.6 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME_FRS2_MEDIATED_CASCADE Genes involved in FRS2-mediated cascade
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events