Motif ID: Foxp1_Foxj2

Z-value: 1.281

Transcription factors associated with Foxp1_Foxj2:

Gene SymbolEntrez IDGene Name
Foxj2 ENSMUSG00000003154.9 Foxj2
Foxp1 ENSMUSG00000030067.11 Foxp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj2mm10_v2_chr6_+_122819888_1228199380.845.4e-12Click!
Foxp1mm10_v2_chr6_-_99028874_990289420.443.7e-03Click!


Activity profile for motif Foxp1_Foxj2.

activity profile for motif Foxp1_Foxj2


Sorted Z-values histogram for motif Foxp1_Foxj2

Sorted Z-values for motif Foxp1_Foxj2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp1_Foxj2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_66386292 9.765 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr8_-_84773381 8.159 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr4_-_151108244 7.424 ENSMUST00000131948.1
 Camta1
calmodulin binding transcription activator 1
chr16_-_43979050 7.295 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr5_+_122643878 6.900 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
 P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr4_-_87806296 6.808 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr1_+_66386968 6.494 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr9_-_121495678 6.245 ENSMUST00000035120.4
 Cck
cholecystokinin
chr15_-_58214882 6.241 ENSMUST00000022986.6
 Fbxo32
F-box protein 32
chr6_-_148444336 6.120 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr9_-_40455670 6.032 ENSMUST00000165104.1
ENSMUST00000045682.5
 Gramd1b

GRAM domain containing 1B

chr10_+_60106452 5.738 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr16_-_34263179 5.354 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr11_+_69095217 5.098 ENSMUST00000101004.2
 Per1
period circadian clock 1
chr4_+_144892813 5.030 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr16_+_91269759 4.895 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr6_+_8520008 4.803 ENSMUST00000162567.1
ENSMUST00000161217.1
 Glcci1

glucocorticoid induced transcript 1

chr7_+_82175156 4.718 ENSMUST00000180243.1
 Sh3gl3
SH3-domain GRB2-like 3
chr6_-_39725193 4.635 ENSMUST00000101497.3
 Braf
Braf transforming gene
chr8_-_11008458 4.522 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 381 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 12.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 12.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.1 12.0 GO:0042572 retinol metabolic process(GO:0042572)
0.6 11.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
1.4 11.2 GO:0060137 maternal process involved in parturition(GO:0060137)
0.8 11.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 11.0 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.7 10.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.4 10.7 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
1.0 10.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.7 9.2 GO:0070842 aggresome assembly(GO:0070842)
1.8 8.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.5 8.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.9 7.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
2.3 6.9 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
1.7 6.9 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.4 6.8 GO:0018345 protein palmitoylation(GO:0018345)
1.0 6.7 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.2 6.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
2.2 6.6 GO:0043379 memory T cell differentiation(GO:0043379)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 162 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 30.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 22.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 16.3 GO:0005802 trans-Golgi network(GO:0005802)
0.5 15.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 11.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 10.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 10.4 GO:0000139 Golgi membrane(GO:0000139)
0.2 9.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.6 9.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 7.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 7.5 GO:0031941 filamentous actin(GO:0031941)
0.7 6.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 6.5 GO:0035861 site of double-strand break(GO:0035861)
0.3 6.4 GO:0031430 M band(GO:0031430)
0.0 6.4 GO:0005874 microtubule(GO:0005874)
0.4 6.2 GO:0043203 axon hillock(GO:0043203)
0.2 6.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 5.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 5.6 GO:0030057 desmosome(GO:0030057)
0.3 5.4 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 252 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 18.7 GO:0030507 spectrin binding(GO:0030507)
0.2 12.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 12.3 GO:0017124 SH3 domain binding(GO:0017124)
1.7 12.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 11.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 11.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 10.1 GO:0042287 MHC protein binding(GO:0042287)
0.1 9.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 8.6 GO:0008017 microtubule binding(GO:0008017)
0.3 8.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 7.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
2.6 7.7 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.2 7.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
1.2 6.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.0 6.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.8 6.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 6.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 6.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.5 5.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 5.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 16.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 12.8 PID_FOXO_PATHWAY FoxO family signaling
0.3 9.7 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.2 9.7 PID_LKB1_PATHWAY LKB1 signaling events
0.2 7.4 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.2 7.3 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.2 7.0 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 5.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.2 5.7 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 5.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 4.9 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.2 4.6 PID_EPO_PATHWAY EPO signaling pathway
0.2 4.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 4.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 4.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.2 4.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 3.8 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 3.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 2.9 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 2.9 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.1 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 10.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.3 9.0 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 7.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 7.8 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 7.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.7 7.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 6.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 6.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 5.7 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.4 4.9 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5 4.7 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 4.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 4.5 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.2 4.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 4.1 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.5 3.9 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.3 3.7 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.9 3.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 3.5 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression