Motif ID: Foxq1

Z-value: 1.117


Transcription factors associated with Foxq1:

Gene SymbolEntrez IDGene Name
Foxq1 ENSMUSG00000038415.8 Foxq1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxq1mm10_v2_chr13_+_31558157_315581760.067.3e-01Click!


Activity profile for motif Foxq1.

activity profile for motif Foxq1


Sorted Z-values histogram for motif Foxq1

Sorted Z-values for motif Foxq1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxq1

PNG image of the network

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Top targets:


Showing 1 to 20 of 120 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_30353468 10.497 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr16_+_43363855 10.348 ENSMUST00000156367.1
 Zbtb20
zinc finger and BTB domain containing 20
chrX_-_103483205 10.054 ENSMUST00000127786.2
 Xist
inactive X specific transcripts
chr16_+_43364145 8.734 ENSMUST00000148775.1
 Zbtb20
zinc finger and BTB domain containing 20
chr2_-_77519565 8.055 ENSMUST00000111830.2
 Zfp385b
zinc finger protein 385B
chr2_+_76406529 6.463 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
 Osbpl6


oxysterol binding protein-like 6


chr5_+_122643878 6.425 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
 P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr17_+_35076902 5.863 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr5_-_122002340 5.293 ENSMUST00000134326.1
 Cux2
cut-like homeobox 2
chr1_-_170110491 5.291 ENSMUST00000027985.2
 Ddr2
discoidin domain receptor family, member 2
chr18_+_37496997 5.250 ENSMUST00000059571.5
 Pcdhb19
protocadherin beta 19
chr4_-_87806276 5.240 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_-_87806296 5.075 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr18_-_89769479 4.717 ENSMUST00000097495.3
 Dok6
docking protein 6
chr18_+_69344503 4.526 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr19_-_28963863 4.382 ENSMUST00000161813.1
 4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr15_-_58214882 4.333 ENSMUST00000022986.6
 Fbxo32
F-box protein 32
chr17_+_35077080 4.046 ENSMUST00000172959.1
 Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr8_-_84773381 3.990 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr10_+_60106452 3.967 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 19.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 14.6 GO:0007416 synapse assembly(GO:0007416)
2.6 10.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.6 10.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
3.4 10.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 9.9 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.1 7.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 7.4 GO:0006869 lipid transport(GO:0006869)
2.1 6.4 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
0.2 5.4 GO:0007614 short-term memory(GO:0007614)
0.7 5.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.4 4.5 GO:0042118 endothelial cell activation(GO:0042118)
2.2 4.3 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 4.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.2 3.6 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.4 3.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 3.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 2.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 2.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 2.7 GO:0045793 positive regulation of cell size(GO:0045793)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 22.0 GO:0005887 integral component of plasma membrane(GO:0005887)
1.0 10.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 10.3 GO:0008023 transcription elongation factor complex(GO:0008023)
1.0 10.1 GO:0000805 X chromosome(GO:0000805)
0.0 7.2 GO:0001650 fibrillar center(GO:0001650)
0.2 6.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.4 6.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 5.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 4.5 GO:0032993 protein-DNA complex(GO:0032993)
0.1 4.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 3.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 2.8 GO:0072686 mitotic spindle(GO:0072686)
0.6 2.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 2.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.7 GO:0055037 recycling endosome(GO:0055037)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 1.5 GO:0033263 CORVET complex(GO:0033263)
0.1 1.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.1 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 25.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.3 10.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
3.3 9.9 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 9.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 7.7 GO:0005509 calcium ion binding(GO:0005509)
1.1 6.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.6 5.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.1 4.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 4.3 GO:0002039 p53 binding(GO:0002039)
0.0 4.1 GO:0008017 microtubule binding(GO:0008017)
0.1 3.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 3.5 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.2 2.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 2.4 GO:0003823 antigen binding(GO:0003823)
0.5 2.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 2.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 2.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 2.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 1.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.3 PID_FOXO_PATHWAY FoxO family signaling
0.0 3.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 3.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 2.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 6.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 4.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.1 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.0 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.8 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events