Motif ID: Gata6

Z-value: 0.419


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Showing 1 to 20 of 76 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_86732409 1.758 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr11_+_67586675 1.218 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr2_+_65930117 1.197 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr8_+_45628176 1.179 ENSMUST00000130850.1
 Sorbs2
sorbin and SH3 domain containing 2
chr6_+_58833689 1.174 ENSMUST00000041401.8
 Herc3
hect domain and RLD 3
chr9_+_66350465 1.116 ENSMUST00000042824.6
 Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr10_-_62342674 1.095 ENSMUST00000143179.1
ENSMUST00000130422.1
 Hk1

hexokinase 1

chr2_+_68104671 1.043 ENSMUST00000042456.3
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_+_86078070 1.031 ENSMUST00000032069.5
 Add2
adducin 2 (beta)
chr12_+_95692212 1.003 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr1_+_152954966 0.988 ENSMUST00000043313.8
 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr6_+_58831748 0.962 ENSMUST00000126292.1
ENSMUST00000031823.5
 Herc3

hect domain and RLD 3

chr4_+_13751297 0.882 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_45627946 0.836 ENSMUST00000145458.1
 Sorbs2
sorbin and SH3 domain containing 2
chr6_-_23248264 0.806 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr9_-_29963112 0.793 ENSMUST00000075069.4
 Ntm
neurotrimin
chr5_+_76840597 0.786 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
 C530008M17Rik


RIKEN cDNA C530008M17 gene


chr8_+_45627709 0.772 ENSMUST00000134321.1
ENSMUST00000135336.1
 Sorbs2

sorbin and SH3 domain containing 2

chr2_-_7396192 0.723 ENSMUST00000137733.2
 Celf2
CUGBP, Elav-like family member 2
chr5_-_73191848 0.719 ENSMUST00000176910.1
 Fryl
furry homolog-like (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 2.1 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 2.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.1 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.0 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 1.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 1.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.5 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.5 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 1.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 1.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 1.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D