Motif ID: Hbp1

Z-value: 0.745


Transcription factors associated with Hbp1:

Gene SymbolEntrez IDGene Name
Hbp1 ENSMUSG00000002996.11 Hbp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hbp1mm10_v2_chr12_-_31950210_31950246-0.443.9e-03Click!


Activity profile for motif Hbp1.

activity profile for motif Hbp1


Sorted Z-values histogram for motif Hbp1

Sorted Z-values for motif Hbp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hbp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_11609256 3.540 ENSMUST00000052902.7
 Gm9797
predicted pseudogene 9797
chr19_+_38481057 2.818 ENSMUST00000182481.1
 Plce1
phospholipase C, epsilon 1
chr10_+_57784914 2.758 ENSMUST00000165013.1
 Fabp7
fatty acid binding protein 7, brain
chr7_-_79386943 2.563 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr10_+_57784859 2.140 ENSMUST00000020024.5
 Fabp7
fatty acid binding protein 7, brain
chr13_-_66852017 1.908 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr8_+_12395287 1.833 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr17_-_32166879 1.805 ENSMUST00000087723.3
 Notch3
notch 3
chr13_-_113046357 1.739 ENSMUST00000022282.3
 Gpx8
glutathione peroxidase 8 (putative)
chr9_-_21760275 1.683 ENSMUST00000098942.4
 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr13_+_65512678 1.643 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr4_-_58499398 1.623 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr12_-_10900296 1.541 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr6_-_82774448 1.533 ENSMUST00000000642.4
 Hk2
hexokinase 2
chr19_-_32466575 1.444 ENSMUST00000078034.3
 Rpl9-ps6
ribosomal protein L9, pseudogene 6
chrY_-_1245753 1.413 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr3_+_98013503 1.384 ENSMUST00000079812.6
 Notch2
notch 2
chr19_-_53589067 1.377 ENSMUST00000095978.3
 Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr17_+_17402672 1.348 ENSMUST00000115576.2
 Lix1
limb expression 1 homolog (chicken)
chr2_+_118814195 1.344 ENSMUST00000110842.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 199 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.9 GO:0060134 prepulse inhibition(GO:0060134)
0.5 3.2 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 2.8 GO:0032835 glomerulus development(GO:0032835)
0.1 2.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 2.6 GO:0007601 visual perception(GO:0007601)
0.1 2.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.3 1.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.3 1.7 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.1 1.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.4 1.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 1.6 GO:0019532 oxalate transport(GO:0019532)
0.0 1.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 1.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.2 1.3 GO:0000279 M phase(GO:0000279)
0.0 1.2 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.2 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 1.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.1 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 1.1 GO:0006414 translational elongation(GO:0006414)
0.1 1.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 1.7 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.6 GO:0070469 respiratory chain(GO:0070469)
0.1 1.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.2 1.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 0.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 143 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 2.6 GO:0016918 retinal binding(GO:0016918)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.6 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.6 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 1.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 1.4 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.3 1.1 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 2.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 2.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.4 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.1 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.9 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.7 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID_MYC_PATHWAY C-MYC pathway
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.7 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.2 3.2 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.3 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 1.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.3 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.2 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 1.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 1.0 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.0 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 0.9 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 0.9 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.9 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA