Motif ID: Hey2
Z-value: 0.652

Transcription factors associated with Hey2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hey2 | ENSMUSG00000019789.8 | Hey2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hey2 | mm10_v2_chr10_-_30842765_30842801 | -0.36 | 2.0e-02 | Click! |
Top targets:
Showing 1 to 20 of 175 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 72 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 6.9 | GO:0001977 | renal system process involved in regulation of blood volume(GO:0001977) |
0.1 | 5.7 | GO:0045214 | sarcomere organization(GO:0045214) |
0.6 | 3.1 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
0.3 | 2.6 | GO:0090166 | Golgi disassembly(GO:0090166) regulation of chaperone-mediated autophagy(GO:1904714) |
0.1 | 2.4 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
0.0 | 2.1 | GO:0007601 | visual perception(GO:0007601) |
0.0 | 1.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.4 | 1.8 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
0.4 | 1.7 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) |
0.1 | 1.6 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.7 | 1.4 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) |
0.0 | 1.2 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 1.1 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 1.1 | GO:0060325 | face morphogenesis(GO:0060325) |
0.2 | 1.0 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
0.1 | 1.0 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.3 | 0.9 | GO:0099552 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
0.1 | 0.9 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.9 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.0 | 0.9 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 38 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.7 | GO:0043034 | costamere(GO:0043034) |
0.1 | 3.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.2 | 3.1 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.0 | 2.6 | GO:0005795 | Golgi stack(GO:0005795) |
0.1 | 2.0 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 1.9 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 1.8 | GO:0038037 | G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) |
0.2 | 1.6 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.0 | 1.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.1 | 1.1 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.3 | 1.0 | GO:0044194 | cytolytic granule(GO:0044194) |
0.1 | 0.9 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.1 | 0.9 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.9 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.1 | 0.8 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.8 | GO:0035102 | PRC1 complex(GO:0035102) |
0.0 | 0.8 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 0.7 | GO:0000242 | pericentriolar material(GO:0000242) |
0.0 | 0.7 | GO:0014704 | intercalated disc(GO:0014704) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 49 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 6.9 | GO:0033764 | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764) |
0.1 | 6.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 3.2 | GO:0003924 | GTPase activity(GO:0003924) |
0.0 | 3.1 | GO:0002020 | protease binding(GO:0002020) |
0.3 | 2.4 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.0 | 2.3 | GO:0002039 | p53 binding(GO:0002039) |
0.1 | 1.9 | GO:0098632 | protein binding involved in cell-cell adhesion(GO:0098632) |
0.4 | 1.8 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) |
0.0 | 1.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 1.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.7 | 1.4 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
0.1 | 1.2 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 1.2 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 1.0 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.1 | 0.9 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.0 | 0.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.2 | 0.8 | GO:0043532 | angiostatin binding(GO:0043532) |
0.1 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 0.8 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
Gene overrepresentation in C2:CP category:
Showing 1 to 14 of 14 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.7 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 3.3 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 2.7 | PID_P73PATHWAY | p73 transcription factor network |
0.0 | 1.2 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 0.8 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.8 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
0.0 | 0.7 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 0.7 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 0.6 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 0.6 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 0.5 | PID_RHOA_PATHWAY | RhoA signaling pathway |
0.0 | 0.4 | ST_STAT3_PATHWAY | STAT3 Pathway |
0.0 | 0.4 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.2 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 27 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.4 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 2.3 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.2 | 2.0 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 2.0 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 1.8 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 1.4 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.1 | 1.2 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 1.2 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
0.0 | 1.2 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 0.8 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.8 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 0.8 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 0.7 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 0.7 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.1 | 0.6 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.0 | 0.6 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 0.5 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
0.0 | 0.5 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.5 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.5 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |