Motif ID: Hnf1b
Z-value: 0.648
Transcription factors associated with Hnf1b:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hnf1b | ENSMUSG00000020679.5 | Hnf1b |
Top targets:
Showing 1 to 20 of 110 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 57 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 5.8 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.9 | 3.5 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) negative regulation of low-density lipoprotein particle clearance(GO:0010989) positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805) |
| 0.8 | 3.1 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
| 0.1 | 3.0 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.9 | 2.8 | GO:0003195 | tricuspid valve formation(GO:0003195) |
| 0.1 | 2.8 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.1 | 2.7 | GO:0072698 | protein localization to microtubule cytoskeleton(GO:0072698) |
| 0.1 | 2.4 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.7 | 2.2 | GO:0090118 | receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) |
| 0.2 | 2.0 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 1.9 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.4 | 1.7 | GO:0050748 | negative regulation of lipoprotein metabolic process(GO:0050748) |
| 0.0 | 1.7 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
| 0.3 | 1.6 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.3 | 1.6 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.3 | 1.4 | GO:0015705 | iodide transport(GO:0015705) |
| 0.3 | 1.4 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
| 0.3 | 1.3 | GO:0072757 | cellular response to camptothecin(GO:0072757) |
| 0.2 | 1.3 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.0 | 1.3 | GO:0006414 | translational elongation(GO:0006414) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.5 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 4.4 | GO:0005814 | centriole(GO:0005814) |
| 1.2 | 3.5 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.4 | 3.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 2.8 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 2.7 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 2.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 2.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.6 | 2.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.0 | 1.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.4 | 1.7 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.1 | 1.6 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 1.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 1.4 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.2 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 1.2 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 1.1 | GO:0010369 | chromocenter(GO:0010369) |
| 0.3 | 1.0 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 0.0 | 0.9 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.0 | 0.9 | GO:0036126 | sperm flagellum(GO:0036126) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 42 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.8 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 1.2 | 3.5 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
| 1.0 | 3.1 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.9 | 2.8 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.0 | 2.7 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 2.5 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.2 | 2.2 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.5 | 2.0 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.1 | 2.0 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.0 | 1.9 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 1.7 | GO:0016209 | antioxidant activity(GO:0016209) |
| 0.1 | 1.6 | GO:0008143 | poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266) |
| 0.4 | 1.4 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.1 | 1.4 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.1 | 1.4 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.3 | 1.3 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
| 0.0 | 1.3 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.2 | 1.2 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.3 | 1.0 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.2 | 1.0 | GO:0015254 | glycerol channel activity(GO:0015254) |
Gene overrepresentation in C2:CP category:
Showing 1 to 12 of 12 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.2 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.1 | 4.0 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 2.5 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 2.2 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.1 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.1 | 1.0 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.7 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.6 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.5 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.4 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.4 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.3 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 16 of 16 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.8 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 3.4 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 3.1 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.1 | 2.0 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 2.0 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 1.8 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 1.3 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 1.0 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 1.0 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.8 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 0.7 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.7 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.6 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 0.5 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.5 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.3 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
